Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Gianluca, Gragnano"'
Autor:
Davide Seminati, Vincenzo L'Imperio, Gabriele Casati, Joranda Ceku, Daniela Pilla, Carla Rossana Scalia, Gianluca Gragnano, Francesco Pepe, Pasquale Pisapia, Luca Sala, Diego Luigi Cortinovis, Francesca Bono, Umberto Malapelle, Giancarlo Troncone, Silvia Novello, Fabio Pagni
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e29272- (2024)
Background: The molecular diagnostic and therapeutic pathway of Non-Small Cell Lung Cancer (NSCLC) stands as a successful example of precision medicine. The scarcity of material and the increasing number of biomarkers to be tested have prompted the r
Externí odkaz:
https://doaj.org/article/8f0aa46a90554e4cba024ba4d722c325
Autor:
Caterina De Luca, Francesco Pepe, Gianluca Russo, Mariantonia Nacchio, Pasquale Pisapia, Maria Russo, Floriana Conticelli, Lucia Palumbo, Claudia Scimone, Domenico Cozzolino, Gianluca Gragnano, Antonino Iaccarino, Giancarlo Troncone, Umberto Malapelle
Publikováno v:
Journal of Molecular Pathology, Vol 4, Iss 4, Pp 259-274 (2023)
Aims: To date, precision medicine has played a pivotal role in the clinical administration of solid-tumor patients. In this scenario, a rapidly increasing number of predictive biomarkers have been approved in diagnostic practice or are currently bein
Externí odkaz:
https://doaj.org/article/742f6e9fbf874375aa788e7768a984e5
Autor:
Caterina de Luca, Gianluca Russo, Mariantonia Nacchio, Maria Ingenito, Lucia Palumbo, Gianluca Gragnano, Floriana Conticelli, Maria Russo, Danilo Rocco, Cesare Gridelli, Roberto Bianco, Domenico Galetta, Giancarlo Troncone, Paola Parente, Antonino Iaccarino
Publikováno v:
The Journal of Liquid Biopsy, Vol 2, Iss , Pp 100128- (2023)
Background: Lung cancer is the leading cause of cancer death worldwide. Over the last decade, molecular testing of a growing number of predictive biomarkers has become mandatory in the management of NSCLC patients. However, a major obstacle in routin
Externí odkaz:
https://doaj.org/article/cb61580502a54b7eb33b7dddd64b9c25
Autor:
Pasquale Pisapia, Francesco Pepe, Antonino Iaccarino, Roberta Sgariglia, Mariantonia Nacchio, Gianluca Russo, Gianluca Gragnano, Elalah Mosaieby, Giancarlo Troncone, Umberto Malapelle
Publikováno v:
Journal of Molecular Pathology, Vol 2, Iss 3, Pp 241-254 (2021)
Lung cancer is the leading cause of cancer death worldwide. Despite the emergence of highly effective targeted therapies, up to 30% of advanced stage non-small cell lung cancer (NSCLC) patients do not undergo tissue molecular testing because of scarc
Externí odkaz:
https://doaj.org/article/b04704275452439fa15fd6259557e6fc
Autor:
Paolo Bironzo, Francesco Pepe, Gianluca Russo, Pasquale Pisapia, Gianluca Gragnano, Gabriella Aquino, Silvia Bessi, Simonetta Buglioni, Federico Bartoccini, Giuseppina Ferrero, Michela Anna Bresciani, Paola Francia di Celle, Francesca Sibona, Andrea Giusti, Alessandra Movilia, Renata Mariella Farioli, Alessandra Santoro, Domenico Salemi, Stefania Scarpino, Dino Galafate, Stefania Tommasi, Rosanna Lacalamita, Davide Seminati, Elham Sajjadi, Silvia Novello, Fabio Pagni, Giancarlo Troncone, Umberto Malapelle
Publikováno v:
Diagnostics, Vol 13, Iss 4, p 629 (2023)
Lung cancer remains the leading cause of cancer deaths worldwide. International societies have promoted the molecular analysis of MET proto-oncogene, receptor tyrosine kinase (MET) exon 14 skipping for the clinical stratification of non-small cell lu
Externí odkaz:
https://doaj.org/article/9e1d4d362dda4bec9c5113fcc9e10130
Autor:
Pasquale Pisapia, Francesco Pepe, Antonino Iaccarino, Roberta Sgariglia, Mariantonia Nacchio, Floriana Conticelli, Maria Salatiello, Rossella Tufano, Gianluca Russo, Gianluca Gragnano, Ilaria Girolami, Albino Eccher, Umberto Malapelle, Giancarlo Troncone
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Molecular cytopathology is a rapidly evolving field embracing both conventional microscopy and molecular pathology. Its growing popularity stems from the fact that in many types of advanced cancers, including non small cell lung cancer (NSCLC), cytol
Externí odkaz:
https://doaj.org/article/197214dfb4c04874966ee0ec43e3ab09
Autor:
Umberto Malapelle, Paola Parente, Francesco Pepe, Caterina De Luca, Pasquale Pisapia, Roberta Sgariglia, Mariantonia Nacchio, Gianluca Gragnano, Gianluca Russo, Floriana Conticelli, Claudio Bellevicine, Elena Vigliar, Antonino Iaccarino, Claudia Covelli, Mariangela Balistreri, Celeste Clemente, Giovanni Perrone, Angela Danza, Fabio Scaramuzzi, Matteo Fassan, Giancarlo Troncone, Paolo Graziano
Publikováno v:
Cells, Vol 10, Iss 8, p 1878 (2021)
Immune-checkpoint inhibitors (ICIs) play a key role in the treatment of advanced stage colorectal cancer (CRC) patients featuring a deficient DNA mismatch repair (dMMR) system or a high microsatellite instability (MSI-H) profile. However, beyond the
Externí odkaz:
https://doaj.org/article/544f7bbcbfa2417aa5d28f9107fd3d82
Autor:
Pasquale Pisapia, Francesco Pepe, Antonino Iaccarino, Roberta Sgariglia, Mariantonia Nacchio, Gianluca Russo, Gianluca Gragnano, Umberto Malapelle, Giancarlo Troncone
Publikováno v:
Cells, Vol 9, Iss 12, p 2549 (2020)
Gain-of-function of V-Raf Murine Sarcoma Viral Oncogene Homolog B (BRAF) is one of the most frequent oncogenic mutations in numerous cancers, including thyroid papillary carcinoma, melanoma, colon, and lung carcinomas, and to a lesser extent, ovarian
Externí odkaz:
https://doaj.org/article/a41c64bdd5054caaba523f512c824b94
Autor:
Francesco Pepe, Antonino Iaccarino, Roberta Sgariglia, Gianluca Russo, G. Troncone, Umberto Malapelle, Mariantonia Nacchio, Elalah Mosaieby, Pasquale Pisapia, Gianluca Gragnano
Publikováno v:
Journal of Molecular Pathology, Vol 2, Iss 21, Pp 241-254 (2021)
Lung cancer is the leading cause of cancer death worldwide. Despite the emergence of highly effective targeted therapies, up to 30% of advanced stage non-small cell lung cancer (NSCLC) patients do not undergo tissue molecular testing because of scarc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f536715641917e3d0d59035cc7c31437
https://www.mdpi.com/2673-5261/2/3/21
https://www.mdpi.com/2673-5261/2/3/21
Autor:
Elena Vigliar, Ilaria Migliatico, Giancarlo Troncone, Maria Giovanna Russo, Umberto Malapelle, Maria Salatiello, Antonino Iaccarino, Gianluca Gragnano, Caterina De Luca, Claudio Bellevicine
Publikováno v:
Cytopathology
Over the past decade, immunotherapy has emerged as one of the most promising cancer treatments. Several monoclonal antibodies targeting the programmed death 1 (PD‐1)/ programmed death ligand‐1 (PD‐L1) pathway have been integrated into standard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f3a82367a8c19342af82b702ea5df0
http://europepmc.org/articles/PMC8453493
http://europepmc.org/articles/PMC8453493