Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Gianluca, Gallo"'
Autor:
Gianluca Gallo
Publikováno v:
Communicative & Integrative Biology, Vol 17, Iss 1 (2024)
ABSTRACTGlycolysis is a metabolic pathway that directly generates adenosine triphosphate (ATP), provides metabolic intermediates for anabolism, and supports mitochondrial oxidative phosphorylation. This review addresses recent advances in our underst
Externí odkaz:
https://doaj.org/article/202f12eb128649ec9cbd9a3540de3e2b
Autor:
Sabrina M Holland, Gianluca Gallo
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 10, Pp 2109-2110 (2024)
Externí odkaz:
https://doaj.org/article/93751a73f4d04d2ca660ddfddbe5f7b6
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Axon branching is a fundamental aspect of neuronal morphogenesis, neuronal circuit formation, and response of the nervous system to injury. Sterile alpha and TIR motif containing 1 (SARM1) was initially identified as promoting Wallerian degeneration
Externí odkaz:
https://doaj.org/article/ad085bec591c47288a9057d1cf985ed1
Autor:
Rajiv Sainath, Gianluca Gallo
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Nerve Growth Factor (NGF) promotes the elaboration of axonal filopodia and branches through PI3K-Akt. NGF activates the TrkA receptor resulting in an initial transient high amplitude burst of PI3K-Akt signaling followed by a maintained lower steady s
Externí odkaz:
https://doaj.org/article/cc4f81b5a2274165924fb66c7d9ef054
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
It is well established that CNS axons fail to regenerate, undergo retrograde dieback, and form dystrophic growth cones due to both intrinsic and extrinsic factors. We sought to investigate the role of axonal mitochondria in the axonal response to inj
Externí odkaz:
https://doaj.org/article/05544ae10b3943f3a07bfc0a80247d43
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
After an injury to the central nervous system (CNS), functional recovery is limited by the inability of severed axons to regenerate and form functional connections with appropriate target neurons beyond the injury. Despite tremendous advances in our
Externí odkaz:
https://doaj.org/article/2ce875860c3f4736a35ce37481236bdf
Autor:
Lorena Armijo-Weingart, Andrea Ketschek, Rajiv Sainath, Almudena Pacheco, George M Smith, Gianluca Gallo
Publikováno v:
eLife, Vol 8 (2019)
Neurotrophins are growth factors that have a multitude of roles in the nervous system. We report that neurotrophins induce the fission of mitochondria along embryonic chick sensory axons driven by combined PI3K and Mek-Erk signaling. Following an ini
Externí odkaz:
https://doaj.org/article/b3648824016e483984f4581d13af0e18
Autor:
Neeharika Nemani, Edmund Carvalho, Dhanendra Tomar, Zhiwei Dong, Andrea Ketschek, Sarah L. Breves, Fabián Jaña, Alison M. Worth, Julie Heffler, Palaniappan Palaniappan, Aparna Tripathi, Ramasamy Subbiah, Massimo F. Riitano, Ajay Seelam, Thomas Manfred, Kie Itoh, Shuxia Meng, Hiromi Sesaki, William J. Craigen, Sudarsan Rajan, Santhanam Shanmughapriya, Jeffrey Caplan, Benjamin L. Prosser, Donald L. Gill, Peter B. Stathopulos, Gianluca Gallo, David C. Chan, Prashant Mishra, Muniswamy Madesh
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 1005-1019 (2018)
Summary: Mitochondria shape cytosolic calcium ([Ca2+]c) transients and utilize the mitochondrial Ca2+ ([Ca2+]m) in exchange for bioenergetics output. Conversely, dysregulated [Ca2+]c causes [Ca2+]m overload and induces permeability transition pore an
Externí odkaz:
https://doaj.org/article/d8a52722cb5c491eaab6dfcbe01c7e01
Autor:
Gianluca Gallo
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 5, Pp 709-711 (2016)
Externí odkaz:
https://doaj.org/article/df78d76151974c458e3605cc540ecb46
Publikováno v:
Cell Reports, Vol 5, Iss 6, Pp 1564-1575 (2013)
The branching of axons is a fundamental aspect of nervous system development and neuroplasticity. We report that branching of sensory axons in the presence of nerve growth factor (NGF) occurs at sites populated by stalled mitochondria. Translational
Externí odkaz:
https://doaj.org/article/9571a0158ac14c72aebdbebb48b2f7a9