Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Gianfranco Olivieri"'
Autor:
Gianfranco Olivieri, F. Müller-Spahn, G. Baysang, Ch. Brack, F. Meier, H. B. Stähelin, M. Brockhaus
Publikováno v:
Journal of Neurochemistry. 76:224-233
Redox changes within neurones are increasingly being implicated as an important causative agent in brain ageing and neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD) and Alzheimer's disease (AD). Cells h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42b03c7a9ebb6dc8d79e05fc708e52f9
https://doi.org/10.1046/j.1471-4159.2001.00090.x
https://doi.org/10.1046/j.1471-4159.2001.00090.x
Autor:
Uwe Otten, G. Baysang, F. Müller-Spahn, Gianfranco Olivieri, F. Meier, B Dimitriades-Schmutz, Egemen Savaskan
Publikováno v:
Neurology & Clinical Neurophysiology. 2002:2-10
The interaction of neurotrophins and their tyrosine kinase receptors (trks) is essential for differentiation and survival of brain cells. In Alzheimer's disease (AD), the number of neurotrophins and receptors is markedly decreased. The cause of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512639b8957e160d66122ee5279f9adf
https://doi.org/10.1162/153840902753658329
https://doi.org/10.1162/153840902753658329
Autor:
Chuong Ly, Gianfranco Olivieri, Egemen Savaskan, Fides Meier, Franz Müller‐Spahn, Manfred Brockhaus, G. Baysang, Christian Hess
Publikováno v:
Journal of Pineal Research. 31:320-325
Heavy metals are increasingly being implicated as causative agents in neurodegenerative diseases such as Alzheimer's disease (AD). Cobalt, a positively charged transition metal, has previously been shown to be in elevated levels in the brain of AD pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5a05975920bc687d60393293b5fa1c7
https://doi.org/10.1034/j.1600-079x.2001.310406.x
https://doi.org/10.1034/j.1600-079x.2001.310406.x
Autor:
Carolyn Rosenberg, Egemen Savaskan, Franz Müller-Spahn, Christine M. Hulette, Christoph Hock, Sybille Bruttel, Gianfranco Olivieri
Publikováno v:
Neurobiology of Aging. 22:541-546
We investigated the immunohistochemical alterations of angiotensin converting enzyme (ACE), angiotensin II and AT1 receptor in the parietal cortex in Alzheimer's dementia (AD) to reveal the contributive role of the brain renin-angiotensin system in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c576f5bde8977e0165ef8aa47bd72c0e
https://doi.org/10.1016/s0197-4580(00)00259-1
https://doi.org/10.1016/s0197-4580(00)00259-1
Publikováno v:
Brain Research. 908:113-119
Post-menopausal estrogen use reduces the risk and severity of Alzheimer's disease (AD). The present study investigates the distribution of both estrogen receptors ER alpha and ER beta in the human hippocampus in aged controls and in AD cases with imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bacf4e9ef30e67f6f8179f93e55dae63
https://doi.org/10.1016/s0006-8993(01)02610-5
https://doi.org/10.1016/s0006-8993(01)02610-5
Autor:
Uwe Otten, Franz Müller-Spahn, Sybille Bruttel, Christoph Hock, Carolyn Rosenberg, Christine M. Hulette, Egemen Savaskan, Gianfranco Olivieri
Publikováno v:
European Neurology. 44:172-180
The neurotrophins nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 bind to the tyrosine kinase (trk) receptors trk A, trk B and trk C, respectively, with high affinity. We investigated the expression of the trk receptors in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2c4ef1ac8d3c9eab4166a3a1a27890
https://doi.org/10.1159/000008229
https://doi.org/10.1159/000008229
Autor:
Erich Seifritz, Zenji Shiozawa, Alison M. Harman, Alvaro Macieira-Coelho, Gianfranco Olivieri, Anthony F. Jorm, Alicia Ahmat, Peter Meyer, Keith Dear, Haruyuki Tanaka, Franz Müller-Spahn, Kazumasa Shindo, Takamura Nagasaka, Egemen Savaskan, Alice MacDonald, Bryan Rodgers, Andrew V. Wister, Fred C.C. Peng, Anna Wirz-Justice, I. Badan, Tanji Hoshi, Haruyasu Ida, Toshiyuki Someya, Masaharu Tanaka, Aurel Popa-Wagner, Shoji Shinkai, Makoto Takahashi, Harue Watanabe, Dieter Platt, Helen Christensen, Fides Meier, Yoshinori Fujiwara, Christof Kessler
Publikováno v:
Gerontology. 49:405-407
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a916706d40191d506b40e8682cbb90e
https://doi.org/10.1159/000075021
https://doi.org/10.1159/000075021
Autor:
C. Warren Olanow, Dirk Sauer, Jean P. Hubble, Peter A. LeWitt, Karl Kieburtz, Harald Pohlmann, Gianfranco Olivieri, Anthony H.V. Schapira
Publikováno v:
The Lancet. Neurology. 5(12)
Summary Background There is an important unmet medical need in Parkinson's disease for a neuroprotective treatment that slows or stops disease progression. TCH346 is a potent anti-apoptotic drug that protects against loss of dopaminergic neurons in l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1490ba07417662e6100f946f2b6978
https://pubmed.ncbi.nlm.nih.gov/17110271
https://pubmed.ncbi.nlm.nih.gov/17110271
Autor:
Erich Seifritz, Fides Meier, Gianfranco Olivieri, Egemen Savaskan, Franz Müller-Spahn, Anna Wirz-Justice
Publikováno v:
Gerontology. 49(6)
Background: β-Amyloid peptide (Aβ), a neutrotoxic substance, has been implicated to a great degree in cell death during the course of AD. Resveratrol, a natural polyphenol mainly found in red wine, has been shown to be cardioprotective and chemopro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1cbc50eaf891d8027a81be4d4ac07f3
https://pubmed.ncbi.nlm.nih.gov/14624067
https://pubmed.ncbi.nlm.nih.gov/14624067
Autor:
Gianfranco Olivieri, G. Baysang, Fides Meier, Franz Müller-Spahn, M. Brockhaus, M Novakovic, Egemen Savaskan
Publikováno v:
Neuroscience. 113(4)
The role of estrogen as a neurotrophic/neuroprotective agent in neurodegenerative diseases such as Alzheimer's and Parkinson's diseases is increasingly being shown. In this study we examine the neuroprotective effects of beta-estradiol on SHSY5Y neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b10e23c0fb0cb5dd2af543f828216a
https://pubmed.ncbi.nlm.nih.gov/12182891
https://pubmed.ncbi.nlm.nih.gov/12182891