Nuclear Receptor Rev-Erb-α Circadian Gene Variants and Lithium Carbonate Prophylaxis in Bipolar Affective Disorder

Autor: Camila Guindalini, Mario Pedrazzoli, S Osborne, Gianfranco Floris, Sergio Tufik, Gerome Breen, Leonardo Tondo, Sara Campos-de-Sousa, Janet Munro, David A. Collier

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Rev-erb-α is one of the key components of the mammalian circadian mechanism; recently, it was also reported to be involved in the biological action of lithium. We investigated whether polymorphisms in the Rev-erb- α gene are associated with the lon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0471cce006ea45e084190e6ccf044c5f
https://doi.org/10.1177/0748730410362713

Latency and episodes before treatment: response to lithium maintenance in bipolar I and II disorders 1

Autor: Gianfranco Floris, John Hennen, Ross J. Baldessarini, Leonardo Tondo

Publikováno v: Bipolar Disorders. 1:91-97

OBJECTIVES To test whether longer treatment-delays or more pretreatment illness episodes are followed by diminished response to lithium maintenance. METHODS In 360 DSM-IV bipolar I (n = 220) or II (n = 140) patients, effects of latency from illness o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bfb4d26d902ad7bd98607edd7ddfd0ab
https://doi.org/10.1034/j.1399-5618.1999.010206.x

Reduced morbidity after gradual discontinuation of lithium treatment for bipolar I and II disorders: a replication study

Autor: Ross J. Baldessarini, N. Rudas, Leonardo Tondo, Gianfranco Floris

Publikováno v: American Journal of Psychiatry. 154:551-553

Objective: The aim of this study was to verify reduction of early affective morbidity by gradual, rather than rapid, discontinuation of lithium treatment. Method: For 78 patients with bipolar disorders, lithium treatment was discontinued either rapid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a375a70178a825663caa238bb3baa2e
https://doi.org/10.1176/ajp.154.4.551

Effects of rapid cycling on response to lithium maintenance treatment in 360 bipolar I and II disorder patients

Autor: John Hennen, Leonardo Tondo, Gianfranco Floris, Ross J. Baldessarini

Publikováno v: Journal of affective disorders. 61(1-2)

Introduction: Rapid cycling (RC) in bipolar disorders is widely believed to predict future morbidity and poor treatment response, although empirical testing of its predictive utility remains limited. Methods: In 360 DSM-IV bipolar I ( N =218) and II

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9d98d9f798121ee183309373d6c7f7
https://pubmed.ncbi.nlm.nih.gov/11099736

Effectiveness of restarting lithium treatment after its discontinuation in bipolar I and bipolar II disorders

Autor: Gianfranco Floris, Leonardo Tondo, N. Rudas, Ross J. Baldessarini

Publikováno v: The American journal of psychiatry. 154(4)

Objective This study tested the hypothesis that resumption of lithium treatment of bipolar disorders may be less effective after maintenance treatment has been discontinued. Method Eighty-six patients with type I or II bipolar disorder, not selected

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9941800ad05367ab4d7df00225a1b7
https://pubmed.ncbi.nlm.nih.gov/9090344