Výsledky vyhledávání - "Gianfranco D. Gaetani"

Radioimmunoassay and chemical properties of glucose-6-phosphate dehydrogenase and of a specific NADP(H)-binding protein (FX) from human erythrocytes

Autor: Monica Galliano, Giorgio Corte, Marco Frascio, Carlotta Gozzer, Gianfranco D. Gaetani, Alessandro Morelli, Lorenzo Minchiotti, Antonio De Flora, Cristina Mareni, Bruno Curti

Publikováno v: Biochimica et Biophysica Acta (BBA) - General Subjects. 500:109-123

Two sensitive radioimmunoassays, based on a double-antibody technique, were developed which allow detection of nanogram amounts of glucose-6-phosphate dehydrogenase (EC 1.1.1.49) and of a so far unknown NADP(H)-binding protein present in human erythr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28729165f560b81fb59186ae6c381143
https://doi.org/10.1016/0304-4165(77)90051-4

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Haemolytic effect of two sulphonamides evaluated by a new method

Autor: Gianfranco D. Gaetani, C. Mareni, R. Ravazzolo, E. Salvidio

Publikováno v: British journal of haematology. 32(2)

A technique to investigate drugs which could cause haemolysis in subjects deficient in glucose-6-phosphate dehydrogenase (D-glucose-6-phosphate: NADP oxidoreductase; G6PD) has been developed. The method is based on the technique of 14CO2 evolution du

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85b992b7ef5da1eccf67a354e42aa4e
https://pubmed.ncbi.nlm.nih.gov/1247492

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Intracellular restraint: a new basis for the limitation in response to oxidative stress in human erythrocytes containing low-activity variants of glucose-6-phosphate dehydrogenase

Autor: Henry N. Kirkman, John C. Parker, Gianfranco D. Gaetani

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 71(9)

Several mechanisms recently proposed for regulation of the hexose monophosphate shunt require the concentration of NADP to be low or that of NADPH to be high. The present study indicates that the first enzyme of the hexose monophosphate shunt of huma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b377e57d677a0d3c40c092686e10b3
https://pubmed.ncbi.nlm.nih.gov/4154443

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Effect of primaquine on erythrocytes with NADH-methaemoglobin reductase deficiency and low glutathione reductase activity

Autor: Giovanna Bianchi, Franco Ajmar, E. Salvidio, Gianfranco D. Gaetani, Cecilia Garrè

Summary. Two young patients with congenital methaemoglobinaemia due to NADH-methaemoglobin reductase deficiency associated with low activity of erythrocytic glutathione reductase (GSSG-R) are described. Their red cells, labelled with 51Cr and transfu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a90f57954354ddacb5cb67f37d8d25e
http://hdl.handle.net/11567/302404

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Glucose-6-Phosphate Deficiency and Inhibition by NADPH: a Self-Contradictory Argument

Autor: Gianfranco D. Gaetani, Henry N. Kirkman

Publikováno v: Science. 190:171-172

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb5b09e3841ee9c068fce2594742c4a
https://doi.org/10.1126/science.241122

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Absence of haemolytic effects of L-DOPA on transfused G6PD-deficient erythrocytes

Autor: E. Salvidio, Ivo Pannacciulli, Gianfranco D. Gaetani, Franco Ajmar, G. F. Paravidino

Publikováno v: Experientia. 26:785-786

Eritrociti G6PD deficienti, marcati con Cr 51, sono stati trasfusi in soggetti normali cui venivano somministrate giornalmente dosi di L-DOPA per via venosa. La L-DOPA viene usata per la terapia del morbo di Parkinson, e causa in vitro una perdita di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75df9a2b02f1ee26454ea825d6932cb1
https://doi.org/10.1007/bf02232551

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