Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Gianella Facchin"'
Publikováno v:
Inorganics, Vol 12, Iss 4, p 97 (2024)
Copper is an essential trace element found ubiquitously in humans [...]
Externí odkaz:
https://doaj.org/article/5f92f2e550d64bc8abfa14d8ac58f7c3
Autor:
Carlos Y. Fernández, Analu Rocha, Mohammad Azam, Natalia Alvarez, Kim Min, Alzir A. Batista, Antonio J. Costa-Filho, Javier Ellena, Gianella Facchin
Publikováno v:
Inorganics, Vol 11, Iss 10, p 398 (2023)
Coordination compounds of copper exhibit cytotoxic activity and are suitable for the search for novel drug candidates for cancer treatment. In this work, we synthesized three copper(II) carboxylate complexes, [Cu2(3-(4-hydroxyphenyl)propanoate)4(H2O)
Externí odkaz:
https://doaj.org/article/a33e4b5eeecd410193bad9a54b3f2520
Autor:
Natalia Alvarez, Analu Rocha, Victoria Collazo, Javier Ellena, Antonio J. Costa-Filho, Alzir A. Batista, Gianella Facchin
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1345 (2023)
Coordination complexes may act as anticancer agents. Among others, the formation of the complex may facilitate the ligand uptake by the cell. Searching for new copper compounds with cytotoxic activity, the complex Cu-dipicolinate was studied as a neu
Externí odkaz:
https://doaj.org/article/a76adc44a34744b0a3bc66ec74b82e55
Autor:
Carlos Y. Fernández, Natalia Alvarez, Analu Rocha, Javier Ellena, Antonio J. Costa-Filho, Alzir A. Batista, Gianella Facchin
Publikováno v:
Molecules, Vol 28, Iss 2, p 896 (2023)
Searching for new copper compounds which may be useful as antitumor drugs, a series of new [Cu(L-dipeptide)(batho)] (batho:4,7-diphenyl-1,10-phenanthroline, L-dipeptide: Gly-Val, Gly-Phe, Ala-Gly, Ala-Ala, Ala-Phe, Phe-Ala, Phe-Val and Phe-Phe) compl
Externí odkaz:
https://doaj.org/article/e25655d39de041259c1033f036143b1f
Autor:
Nicolás Veiga, Natalia Alvarez, Eduardo E. Castellano, Javier Ellena, Gianella Facchin, María H. Torre
Publikováno v:
Molecules, Vol 26, Iss 21, p 6520 (2021)
In a search for new antitumoral agents, a series of homoleptic copper(II) complexes with amino acids and dipeptides, as well as heteroleptic complexes containing both dipeptides and 1,10-phenanthroline, were studied. Furthermore, a single-crystal str
Externí odkaz:
https://doaj.org/article/8756632964bd49de87cc4518d4c35341
Autor:
Natalia Alvarez, Priscilla Freddi, Stephanie Castellani, Nicolás Veiga, Gianella Facchin, Antonio J. Costa-Filho
Publikováno v:
Brazilian Journal of Physics. 52
Autor:
Natalia Alvarez, Celisnolia M. Leite, Adriana Napoleone, Luis F. S. Mendes, Carlos Y. Fernández, Ronny R. Ribeiro, Javier Ellena, Alzir A. Batista, Antonio J. Costa-Filho, Gianella Facchin
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9297fae9a38fb3becf8bc817d0e263f
Autor:
Natalia, Alvarez, Celisnolia M, Leite, Adriana, Napoleone, Luis F S, Mendes, Carlos Y, Fernández, Ronny R, Ribeiro, Javier, Ellena, Alzir A, Batista, Antonio J, Costa-Filho, Gianella, Facchin
Publikováno v:
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 27(4-5)
New compounds to fight cancer are needed due to cancer high incidence and lack of curative treatments for several classes of this disease. Metal-based coordination compounds offer a variety of molecules that can turn into drugs. Among them, coordinat
Autor:
Luis F.S. Mendes, Natalia Alvarez, María H. Torre, M. Gabriela Kramer, Javier Ellena, Gianella Facchin, Antonio J. Costa-Filho
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
In order to seek for new compounds with antitumor activity, our research group is focused on copper complexes with mixed ligands. This work presents the synthesis and characterization of eight compounds with general formula [Cu(iminodiacetate)(diimin
Autor:
Juliana P, da Silva, Otávio, Fuganti, M Gabriela, Kramer, Gianella, Facchin, Lucas E N, Aquino, Javier, Ellena, Davi F, Back, Ana C S, Gondim, Eduardo H S, Sousa, Luiz G F, Lopes, Silvane, Machado, Ivelise D L, Guimarães, Karen, Wohnrath, Márcio P, de Araujo
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 49(45)
Complexes with general formula [RuCl(η6-p-cymene)(P-NR-P)]X (R = CH2Py (Py = pyridine) - [1a]+, CH2Ph (Ph = phenyl) - [1b]+, Ph - [1c] and p-tol (p-tol = p-tolyl) - [1d]+; X = PF6- or BF4-) were evaluated as cytotoxic agents against two cancer cell