Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Giancarlo Forte"'
Publikováno v:
Advanced Science, Vol 11, Iss 8, Pp n/a-n/a (2024)
Abstract The application of lipid‐based nanoparticles for COVID‐19 vaccines and transthyretin‐mediated amyloidosis treatment have highlighted their potential for translation to cancer therapy. However, their use in delivering drugs to solid tum
Externí odkaz:
https://doaj.org/article/96fa762f277b4befbd22cb6fc2da2828
Autor:
Marco Cassani, Soraia Fernandes, Jorge Oliver‐De La Cruz, Helena Durikova, Jan Vrbsky, Marek Patočka, Veronika Hegrova, Simon Klimovic, Jan Pribyl, Doriana Debellis, Petr Skladal, Francesca Cavalieri, Frank Caruso, Giancarlo Forte
Publikováno v:
Advanced Science, Vol 11, Iss 2, Pp n/a-n/a (2024)
Abstract Interactions between living cells and nanoparticles are extensively studied to enhance the delivery of therapeutics. Nanoparticles size, shape, stiffness, and surface charge are regarded as the main features able to control the fate of cell
Externí odkaz:
https://doaj.org/article/c4120ba3908f4da5bb68047683a62753
Autor:
Ece Ergir, Jorge Oliver-De La Cruz, Soraia Fernandes, Marco Cassani, Francesco Niro, Daniel Pereira-Sousa, Jan Vrbský, Vladimír Vinarský, Ana Rubina Perestrelo, Doriana Debellis, Natália Vadovičová, Stjepan Uldrijan, Francesca Cavalieri, Stefania Pagliari, Heinz Redl, Peter Ertl, Giancarlo Forte
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-21 (2022)
Abstract Cardiovascular diseases remain the leading cause of death worldwide; hence there is an increasing focus on developing physiologically relevant in vitro cardiovascular tissue models suitable for studying personalized medicine and pre-clinical
Externí odkaz:
https://doaj.org/article/ba835c5faec74d5db9b6c852abd5cf84
Publikováno v:
Acta Polytechnica CTU Proceedings, Vol 25, Iss 0, Pp 79-82 (2019)
To investigate cellular response of cardiomyocytes to substrate mechanics, biocompatible material with stiffness in physiological range is needed. PDMS based material is used for construction of microfluidic organ on chip devices for cell culture d
Externí odkaz:
https://doaj.org/article/f9223469a4ff47e387ebe4b49965f8e2
Autor:
Federico Tidu, Marco De Zuani, Shyam Sushama Jose, Kamila Bendíčková, Lukáš Kubala, Frank Caruso, Francesca Cavalieri, Giancarlo Forte, Jan Frič
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102683- (2021)
Summary: Mesenchymal stromal cells (MSCs) combined with calcineurin-nuclear factor of activated T cell (CN-NFAT) inhibitors are being tested as a treatment for graft-versus-host disease (GvHD). The immunosuppressive properties of MSCs seem beneficial
Externí odkaz:
https://doaj.org/article/2bb5ad7148694ea1b1ce1d1b1ae8807e
Autor:
Federica Tonon, Maja Cemazar, Urska Kamensek, Cristina Zennaro, Gabriele Pozzato, Sergio Caserta, Flora Ascione, Mario Grassi, Stefano Guido, Cinzia Ferrari, Laura Cansolino, Francesco Trotta, Biljana Grcar Kuzmanov, Giancarlo Forte, Fabiana Martino, Francesca Perrone, Riccardo Bomben, Valter Gattei, Nicola Elvassore, Erminio Murano, Nhung Hai Truong, Michael Olson, Rossella Farra, Gabriele Grassi, Barbara Dapas
Publikováno v:
Cancers, Vol 14, Iss 7, p 1630 (2022)
Background: For hepatocellular carcinoma (HCC), effective therapeutic approaches are lacking. As aberrant gene methylation is a major contributor to HCC development, demethylating drugs such as 5-azacytidine (5-Aza) have been proposed. As most 5-Aza
Externí odkaz:
https://doaj.org/article/3e90d9f36584451fba36239e65146048
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
The research for heart therapies is challenged by the limited intrinsic regenerative capacity of the adult heart. Moreover, it has been hampered by the poor results obtained by tissue engineering and regenerative medicine attempts at generating funct
Externí odkaz:
https://doaj.org/article/d3d50ccab1e3424f8951204ee2e06e11
Autor:
Shyam Sushama Jose, Marco De Zuani, Federico Tidu, Marcela Hortová Kohoutková, Lucia Pazzagli, Giancarlo Forte, Roberta Spaccapelo, Teresa Zelante, Jan Frič
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 5, Pp n/a-n/a (2020)
Abstract Objectives The activation of immune responses in mucosal tissues is a key factor for the development and sustainment of several pathologies including infectious diseases and autoimmune diseases. However, translational research and personalis
Externí odkaz:
https://doaj.org/article/6843c46f262f4f10ac2b732709b9ab12
Autor:
Tomáš Doktor, Ivana Kumpová, Sebastian Wroński, Maciej Śniechowski, Jacek Tarasiuk, Giancarlo Forte, Daniel Kytýř
Publikováno v:
Acta Polytechnica CTU Proceedings, Vol 18, Iss 0, Pp 24-27 (2018)
The paper deals with investigation on directional variations of mechanical response in 3D printed models of human trabecular bone. Sample of trabecular bone tissue was resected from human donor and 3D model was obtained by X-ray computed tomography.
Externí odkaz:
https://doaj.org/article/19912453ae5b4f4cae9b66ffb29dbbc3
Autor:
Giorgia Nardone, Jorge Oliver-De La Cruz, Jan Vrbsky, Cecilia Martini, Jan Pribyl, Petr Skládal, Martin Pešl, Guido Caluori, Stefania Pagliari, Fabiana Martino, Zuzana Maceckova, Marian Hajduch, Andres Sanz-Garcia, Nicola Maria Pugno, Gorazd Bernard Stokin, Giancarlo Forte
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
The transcriptional co-activator YAP is known to operate downstream of mechanical signals arising from the cell niche. Here the authors demonstrate that YAP controls cell mechanics, force development and adhesion strength by promoting the transcripti
Externí odkaz:
https://doaj.org/article/6257312755974ce381c3c1ab209da290