Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Giancarlo A Biagini"'
Autor:
Celina Jin, Malick M Gibani, Shaun H Pennington, Xinxue Liu, Alison Ardrey, Ghaith Aljayyoussi, Maria Moore, Brian Angus, Christopher M Parry, Giancarlo A Biagini, Nicholas A Feasey, Andrew J Pollard
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 12, p e0007955 (2019)
BackgroundThe treatment of enteric fever is complicated by the emergence of antimicrobial resistant Salmonella Typhi. Azithromycin is commonly used for first-line treatment of uncomplicated enteric fever, but the response to treatment may be sub-opti
Externí odkaz:
https://doaj.org/article/9cb2ce75e9304e149217ca0f47e94cda
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58933 (2013)
The intraerythrocytic malaria parasite is susceptible to oxidative stress and this may play a role in the mechanism of action of some antimalarial agents. Here we show that exposure of the intraerythrocytic malaria parasite to the oxidising agent hyd
Externí odkaz:
https://doaj.org/article/3b54eb8918af47a9b6cb8964ba2b79fb
Autor:
Daniel G Wootton, Hyginus Opara, Giancarlo A Biagini, Maxwell K Kanjala, Stephan Duparc, Paula L Kirby, Mary Woessner, Colin Neate, Maggie Nyirenda, Hannah Blencowe, Queen Dube-Mbeye, Thomas Kanyok, Stephen Ward, Malcolm Molyneux, Sam Dunyo, Peter A Winstanley
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e1779 (2008)
The objective of this study was to determine the appropriate dose of artesunate for use in a fixed dose combination therapy with chlorproguanil-dapsone (CPG-DDS) for the treatment of uncomplicated falciparum malaria.Open-label clinical trial comparin
Externí odkaz:
https://doaj.org/article/17da3911aa0143e58c17fdf549eaf367
Autor:
Kieran Collings, Cedric Boisdon, Tung-Ting Sham, Kevin Skinley, Hyun-Kyung Oh, Tessa Prince, Adham Ahmed, Shaun H. Pennington, Philip J. Brownridge, Thomas Edwards, Giancarlo A. Biagini, Claire E. Eyers, Amanda Lamb, Peter Myers, Simon Maher
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The novel coronavirus pandemic (COVID-19) has necessitated a global increase in the use of face masks to limit the airborne spread of the virus. The global demand for personal protective equipment has at times led to shortages of face masks
Externí odkaz:
https://doaj.org/article/409957c3687e47d9895926e953749aae
Autor:
Jordan J. Clark, Rebekah Penrice-Randal, Parul Sharma, Xiaofeng Dong, Shaun H. Pennington, Amy E. Marriott, Stefano Colombo, Andrew Davidson, Maia Kavanagh Williamson, David A. Matthews, Lance Turtle, Tessa Prince, Grant L. Hughes, Edward I. Patterson, Ghada Shawli, Daniele F. Mega, Krishanthi Subramaniam, Jo Sharp, Joseph D. Turner, Giancarlo A. Biagini, Andrew Owen, Anja Kipar, Julian A. Hiscox, James P. Stewart
Publikováno v:
Viruses, Vol 16, Iss 6, p 863 (2024)
COVID-19 is a spectrum of clinical symptoms in humans caused by infection with SARS-CoV-2. The coalescence of SARS-CoV-2 with seasonal respiratory viruses, particularly influenza viruses, is a global health concern. To understand this, transgenic mic
Externí odkaz:
https://doaj.org/article/ce2f20723c1d4989840bfe05c1366c88
Autor:
Keertan Dedha, Henry C Mwandumba, Brian D. Robertson, Nimisha Raj Sharma, Naomi F Walker, Simon Sichone, Shobana Balasingam, Ben Morton, Stephen B. Gordon, Phoebe Hazenberg, Kondwani Jambo, Anthony E. Chirwa, JoAnne Flynn, Zacharia Kafuko, Daniela M. Ferreira, Giancarlo A. Biagini, Sarah Fortune, Helen McShane
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Background: Tuberculosis (TB) remains a major challenge in many domains including diagnosis, pathogenesis, prevention, treatment, drug resistance and long-term protection of the public health by vaccination. A controlled human infection model (CHIM)
Externí odkaz:
https://doaj.org/article/abccf59a8b71451384078d9acd4dcf83
Autor:
Keertan Dedha, Henry Mwandumba, Brian D. Robertson, Nimisha Raj Sharma, Naomi Walker, Simon Sichone, Shobana Balasingam, Ben Morton, Stephen B. Gordon, Phoebe Hazenberg, Kondwani Jambo, Anthony E. Chirwa, Joanne Flynn, Zacharia Kafuko, Daniela M. Ferreira, Giancarlo A. Biagini, Sarah Fortune, Helen McShane
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Background: Tuberculosis (TB) remains a major challenge in many domains including diagnosis, pathogenesis, prevention, treatment, drug resistance and long-term protection of the public health by vaccination. A controlled human infection model (CHIM)
Externí odkaz:
https://doaj.org/article/f3ba22777830446ab853f538dc4a7195
Autor:
Kangsa Amporndanai, Nattapon Pinthong, Paul M. O’Neill, W. David Hong, Richard K. Amewu, Chandrakala Pidathala, Neil G. Berry, Suet C. Leung, Stephen A. Ward, Giancarlo A. Biagini, S. Samar Hasnain, Svetlana V. Antonyuk
Publikováno v:
Biology, Vol 11, Iss 8, p 1109 (2022)
Antimalarials targeting the ubiquinol-oxidation (Qo) site of the Plasmodium falciparum bc1 complex, such as atovaquone, have become less effective due to the rapid emergence of resistance linked to point mutations in the Qo site. Recent findings show
Externí odkaz:
https://doaj.org/article/b74084f8e68b4a56bee023bd1e647e27
Autor:
Laura N. Jeffreys, Alison Ardrey, Taghreed A. Hafiz, Lauri-Anne Dyer, Ashley J. Warman, Nada Mosallam, Gemma L. Nixon, Nicholas E. Fisher, W. David Hong, Suet C. Leung, Ghaith Aljayyoussi, Jaclyn Bibby, Deepak V. Almeida, Paul J. Converse, Nader Fotouhi, Neil G. Berry, Eric L. Nuermberger, Anna M. Upton, Paul M. O’Neill, Stephen A. Ward, Giancarlo A. Biagini
Publikováno v:
ACS Infectious Diseases. 9:221-238
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7bcc98728afc2851b04165451a027f5
https://doi.org/10.1021/acsinfecdis.2c00283
https://doi.org/10.1021/acsinfecdis.2c00283
Autor:
Samantha Donnellan, Shaun H Pennington, Alessandra Ruggiero, Carmen Martinez-Rodriguez, Marion Pouget, Jordan Thomas, Steve A Ward, Georgios Pollakis, Giancarlo A Biagini, William A Paxton
Mycobacterium tuberculosis and human immunodeficiency virus-1 (HIV-1) syndemic interactions are a major global health concern. Despite the clinical significance of coinfection, our understanding of the cellular pathophysiology and the therapeutic pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52582433eac0f3039d35d4d1be86167c
https://hdl.handle.net/11562/1085557
https://hdl.handle.net/11562/1085557
