Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Giancarlo, Carli"'
Autor:
Tal Hoffmann, Florian Klemm, Tatjana I Kichko, Susanne K Sauer, Katrin Kistner, Bernhard Riedl, Patrick Raboisson, Lei Luo, Alexandru Babes, Laurence Kocher, Giancarlo Carli, Michael J. M. Fischer, Peter W. Reeh
Publikováno v:
Physiological Reports, Vol 10, Iss 6, Pp n/a-n/a (2022)
Abstract The most widely used formalin test to screen antinociceptive drug candidates is still apostrophized as targeting inflammatory pain, in spite of strong opposing evidence published. In our rat skin‐nerve preparation ex vivo, recording from a
Externí odkaz:
https://doaj.org/article/1914070659d6462b8e34932dd1b49f99
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Externí odkaz:
https://doaj.org/article/7810764d352f4177b95f889a2ba0ef9c
Publikováno v:
Progress in brain research. 271(1)
In this introductory chapter we describe the ethological basis of defensive behavior, including tonic immobility (TI). The defensive repertoire activated in response to threatening stimuli, both in natural and experimental conditions, consists of a s
Publikováno v:
Progress in brain research. 271(1)
Threatening stimuli challenging animal homeostasis are the primary events triggering defensive responses, including TI. The stress-response system (allostasis) is signaled by increased corticosteroid basal levels. In bird animal lines genetically sel
Publikováno v:
Progress in brain research. 271(1)
In this conclusive chapter, we review findings giving support to the hypothesis that TI represents an adaptive, survival response to threatening situations. In models of prey-predator interactions, in vertebrates and invertebrates, there are evidence
Publikováno v:
Progress in brain research. 271(1)
Serotonin, acetylcholine and GABA are the neuromediators most involved in tonic immobility (TI). TI duration, in fact, decreases in rabbits following systemic serotonin administration and in guinea pigs following serotonin microinjection administrati
Publikováno v:
Progress in brain research. 271(1)
Innate fear-related behavioral responses have evolved as strategies for survival. The neural circuits responsible for defensive responses, studied mainly in rodents, have been substantially preserved across evolution. Amygdala collects sensory inform
Publikováno v:
Progress in brain research. 271(1)
Lower invertebrates exhibit both morphological and behavioral defensive responses to aversive stimuli, characterized by withdrawal. Typical immobility responses are "sinking" in Rotifers and "crumpling" in Cnidaria. They also display individual adapt
Publikováno v:
Progress in brain research. 271(1)
This chapter deals with the mechanisms modulating pain during TI and other immobility responses in different animal species. In mammals the presence of high voltage slow waves in the electroencephalogram during TI suggests the activation of the thala
Publikováno v:
Progress in brain research. 271(1)
Animal models of autonomic correlates of defense behavior range from fish to mammals. There is however no study reporting heart and respiratory rate, blood pressure and body temperature simultaneously recorded in the same animal in association to dif