Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Gian Pietro Sgaragli"'
Autor:
Gian Pietro Sgaragli, Miriam Durante, Simona Saponara, Pham Ngoc Khanh, Tran Thu Huong, Nguyen Manh Cuong, Paolo Mugnai, N. T Son, Fabio Fusi, Ottavia Spiga
Publikováno v:
British Journal of Pharmacology. 173:292-304
Background and purpose The carbazole alkaloid murrayafoline A (MuA) enhances contractility and the Ca(2+) currents carried by the Cav 1.2 channels [ICa1.2 ] of rat cardiomyocytes. As only few drugs stimulate ICa1.2 , this study was designed to analys
Autor:
Fabio Fusi, Gian Pietro Sgaragli
Publikováno v:
Phytotherapy Research. 29:628-631
Chronically administered organic nitrates induce nitrate tolerance and endothelial dysfunction, which limit their therapeutic use. eNOS uncoupling, ROS over-production, aldehyde dehydrogenase-2 as well as superoxide dismutase (SOD) oxidative inhibiti
Autor:
Fabio Fusi, Gian Pietro Sgaragli, Simona Saponara, Paolo Mugnai, Sergio Bova, Miriam Durante, G. Paliuri
Publikováno v:
Acta Physiologica. 211:334-345
Aim: To develop a cheap and simple method of storing for 24-h vascular tissue and single myocytes while preserving therein the biophysical and pharmacological characteristics of L-type Ca 2+ channels and contractile activity. Methods: Rings or vascul
Autor:
Gian Pietro Sgaragli, Eugenio Bertelli, Giulia Franco, Massimo Valoti, Marì Regoli, Vittorio Morandi, Monica Bracciali, Stefania Dragoni
Publikováno v:
Toxicological sciences
128 (2012): 186–197. doi:10.1093/toxsci/kfs150
info:cnr-pdr/source/autori:Stefania Dragoni, Giulia Franco, Marì Regoli, Monica Bracciali, Vittorio Morandi, Giampietro Sgaragli, Eugenio Bertelli, Massimo Valoti/titolo:Gold Nanoparticles Uptake and Cytotoxicity Assessed on Rat Liver Precision-Cut Slices/doi:10.1093%2Ftoxsci%2Fkfs150/rivista:Toxicological sciences (Print)/anno:2012/pagina_da:186/pagina_a:197/intervallo_pagine:186–197/volume:128
128 (2012): 186–197. doi:10.1093/toxsci/kfs150
info:cnr-pdr/source/autori:Stefania Dragoni, Giulia Franco, Marì Regoli, Monica Bracciali, Vittorio Morandi, Giampietro Sgaragli, Eugenio Bertelli, Massimo Valoti/titolo:Gold Nanoparticles Uptake and Cytotoxicity Assessed on Rat Liver Precision-Cut Slices/doi:10.1093%2Ftoxsci%2Fkfs150/rivista:Toxicological sciences (Print)/anno:2012/pagina_da:186/pagina_a:197/intervallo_pagine:186–197/volume:128
A major obstacle in the field of nanotoxicology is the development of an in vitro model that accurately predicts an in vivo response. To address this concern, rat liver precision-cut slices were used to assess the impact of 5-nm gold nanoparticles (G
Publikováno v:
Amino Acids. 42:2139-2147
The activation of the GABAergic system has been shown to protect brain tissues against the damage that occurs after cerebral ischaemia. On the other hand, the taurine analogues (±)Piperidine-3-sulphonic- (PSA), 2-aminoethane phosphonic- (AEP), 2-(N-
Autor:
Carlo Aldinucci, Alberto Benocci, Mitri Palmi, Gian Pietro Sgaragli, Julian Blanco Garcia, Antonella Meini, Gian Paolo Pessina, Maria Frosini
Publikováno v:
European Journal of Neuroscience. 17:692-700
The relationship between nitric oxide (NO) and intracellular Ca 2 + in hypoxic-ischemic brain damage is not known in detail. Here we used rat striatal slices perfused under low-oxygen and Ca 2 + -free conditions and cultured human astrocytoma cells i
Publikováno v:
Pharmacology. 68:9-16
An acute inflammatory response begins during the reperfusion phase following an ischemic insult in which polymorphonuclear neutrophils (PMNs) play an important role and the release of reactive oxygen species (ROS) causes further damage and a reductio
Publikováno v:
Canadian journal of physiology and pharmacology. 92(2)
The effect of freeze-dried red wine (FDRW) on cardiac function and electrocardiogram (ECG) in Langendorff-isolated rat hearts was investigated. FDRW significantly decreased left ventricular pressure and coronary perfusion pressure, the latter being d
Publikováno v:
Acta Physiologica Scandinavica. 173:257-265
The aim of the present study was to characterize voltage-gated Ca 2+ currents in smooth muscle cells freshly isolated from rat tail main artery in the presence of 5 mmol L -1 external Ca 2+ Calcium currents were identified on the basis of their volta
Autor:
Fabio Fusi, Keith F. Tipton, Mitri Palmi, Maria Frosini, Gian Pietro Sgaragli, Henry B. F. Dixon, Gisèle Tchuisseu Youmbi
Publikováno v:
Biochemical Pharmacology. 58:1123-1131
The effects of taurine (2-aminoethanesulphonic acid) and its analogues, 2-aminoethylarsonic acid, 2-hydroxyethanesulphonic (isethionic) acid, 3-aminopropanesulphonic acid, 2-aminoethylphosphonic acid, and N,N-dimethyltaurine, were studied on the tran