Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gian Paolo Marcuzzi"'
ATP synthase modulation leads to an increase of spare respiratory capacity in HPV associated cancers
Autor:
Matthias Kirschberg, Sandra Heuser, Gian Paolo Marcuzzi, Martin Hufbauer, Jens Michael Seeger, Anamaria Đukić, Vjekoslav Tomaić, Slawomir Majewski, Steffen Wagner, Claus Wittekindt, Nora Würdemann, Jens Peter Klussmann, Alexander Quaas, Hamid Kashkar, Baki Akgül
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Mucosal and skin cancers are associated with infections by human papillomaviruses (HPV). The manner how viral oncoproteins hijack the host cell metabolism to meet their own energy demands and how this may contribute to tumorigenesis is poorl
Externí odkaz:
https://doaj.org/article/11881e22fa564878ac276b326468d4d4
ATP synthase modulation leads to an increase of spare respiratory capacity in HPV associated cancers
Autor:
Gian Paolo Marcuzzi, N. Würdemann, Jens M. Seeger, Steffen Wagner, Anamaria Đukić, Matthias Kirschberg, Jens Peter Klussmann, Slawomir Majewski, Hamid Kashkar, Alexander Quaas, Baki Akgül, Martin Hufbauer, Vjekoslav Tomaić, Claus Wittekindt, Sandra Heuser
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific reports
Scientific Reports
Scientific reports
Mucosal and skin cancers are associated with infections by human papillomaviruses (HPV). The manner how viral oncoproteins hijack the host cell metabolism to meet their own energy demands and how this may contribute to tumorigenesis is poorly underst
Autor:
Adnan Shahzad Syed, Gian Paolo Marcuzzi, Daliborka Miller-Lazic, Jochen Hess, Martin Hufbauer, Baki Akgül
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1662
K14-HPV8-CER transgenic mice express the complete early genome region of human papillomavirus type 8 (HPV8) and develop skin tumours attributed to the expansion of the Lrig1+ stem cell population. The correlation between HPV8-induced changes in trans
Autor:
Tasuku Honjo, Herbert Pfister, Kazuhiko Koike, Maki Kobayashi, Tung Nguyen, Shunsuke Chikuma, Gian Paolo Marcuzzi, Jianliang Xu, Kazuo Kinoshita, Kyoji Moriya, Hiroshi Hiai
Publikováno v:
International Immunology. 26:397-406
Activation-induced cytidine deaminase (AID) not only promotes immune diversity by initiating somatic hypermutation and class switch recombination in immunoglobulin genes but also provokes genomic instability by introducing translocations and mutation
Autor:
Farnoosh Alborzi, Peter Angel, Gian Paolo Marcuzzi, Daliborka Lazić, Herbert Pfister, Jochen Hess, Baki Akgül
Publikováno v:
Journal of Dermatological Science. 62:84-90
Background The human papillomavirus type 8 (HPV8) is associated with the development of non-melanoma skin cancer. Transgenic mice expressing the complete early gene region of HPV8 (E6/E7/E1/E2/E4 = CER) or E6 separately under the control of the kerat
Autor:
Herbert Pfister, Florian Kern, Marisa Gariglio, Santo Landolfo, Manuela Baccarini, Gian Paolo Marcuzzi, Sigrun Smola, Marco De Andrea, Cinzia Borgogna, Manuela M. Landini, Michele Mondini, Karin Ehrenreiter, Massimo Rittà
Publikováno v:
Cancer Research. 70:7938-7948
Human papillomaviruses (HPV) of the genus β are thought to play a role in human skin cancers, but this has been difficult to establish using epidemiologic approaches. To gain insight into the transforming activities of β-HPV, transgenic mouse model
Autor:
Sigrun Smola, Herbert Pfister, S. Weißenborn, Gian Paolo Marcuzzi, Martin Hufbauer, Hans U. Kasper
Publikováno v:
Journal of General Virology. 90:2855-2864
Cutaneous human papillomavirus type 8 (HPV8) is carcinogenic in patients with epidermodysplasia verruciformis. Transgenic mice with the complete early region (CER) of HPV8 spontaneously developed papillomas, dysplasia and squamous cell carcinomas of
Publikováno v:
Cancer research. 75(2)
Beta human papillomaviruses (HPV) have been suspected to be carcinogenic in nonmelanoma skin cancers (NMSC), but the basis for potential viral contributions to these cancers is poorly understood. In particular, it is unresolved how HPV-infected kerat
Autor:
Gian Paolo Marcuzzi, Herbert Pfister, Lysann Schädlich, Sabine A. Eming, Lutz Gissmann, Martin Hufbauer, Sabine Awerkiew
Publikováno v:
Medical microbiology and immunology. 203(3)
The genus beta human papillomavirus 8 (HPV8) is involved in the development of cutaneous squamous cell carcinomas (SCCs) in individuals with epidermodysplasia verruciformis. Immunosuppressed transplant recipients are prone to harbor particularly high