Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Gian Marco Casillo"'
Autor:
Rosangela Montanaro, Valentina Vellecco, Roberta Torregrossa, Gian Marco Casillo, Onorina Laura Manzo, Emma Mitidieri, Mariarosaria Bucci, Sigismondo Castaldo, Raffaella Sorrentino, Matthew Whiteman, Martina Smimmo, Flavia Carriero, Giuseppe Terrazzano, Giuseppe Cirino, Roberta d’Emmanuele di Villa Bianca, Vincenzo Brancaleone
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102657- (2023)
Diabetes is associated with severe vascular complications involving the impairment of endothelial nitric oxide synthase (eNOS) as well as cystathionine γ-lyase (CSE) activity. eNOS function is suppressed in hyperglycaemic conditions, resulting in re
Externí odkaz:
https://doaj.org/article/cfd68478f66f44dd8c2212be1e351e68
Autor:
Valentina Vellecco, Elisabetta Panza, Sofia-Iris Bibli, Gian Marco Casillo, Federica Raucci, Onorina Laura Manzo, Martina Smimmo, Romolo Villani, Maria Rosaria Cavezza, Ingrid Fleming, Roberta d'Emmanuele di Villa Bianca, Francesco Maione, Giuseppe Cirino, Mariarosaria Bucci
Publikováno v:
Pharmacological Research, Vol 177, Iss , Pp 106108- (2022)
The increase in intracellular calcium is influenced by cyclic nucleotides (cAMP and cGMP) content, which rating is governed by phosphodiesterases (PDEs) activity.Despite it has been demonstrated a beneficial effect of PDEs inhibitors in different pat
Externí odkaz:
https://doaj.org/article/57c8ce1cd819431d804e29a15c9e82be
Autor:
Francesco Maione, Gian Marco Casillo, Federica Raucci, Cristian Salvatore, Giovanna Ambrosini, Luisa Costa, Raffaele Scarpa, Francesco Caso, Mariarosaria Bucci
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 142, Iss , Pp 111980- (2021)
One of the hallmarks of COVID-19 is the cytokine storm that provokes primarily pneumonia followed by systemic inflammation. Emerging evidence has identified a potential link between elevated interleukin-17A (IL-17A) levels and disease severity and pr
Externí odkaz:
https://doaj.org/article/fab50d1071414697932343b6e8262b1f
Autor:
Anella Saviano, Gian Marco Casillo, Federica Raucci, Alessia Pernice, Cristina Santarcangelo, Marialuisa Piccolo, Maria Grazia Ferraro, Miriam Ciccone, Alessandro Sgherbini, Nadia Pedretti, Daniele Bonvicini, Carlo Irace, Maria Daglia, Nicola Mascolo, Francesco Maione
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 139, Iss , Pp 111579- (2021)
Alzheimer’s disease (AD) is the most common type of dementia worldwide, characterized by the deposition of neurofibrillary tangles and amyloid-β (Aβ) peptides in the brain. Additionally, increasing evidence demonstrates that a neuroinflammatory s
Externí odkaz:
https://doaj.org/article/989225a64c564a418e6a80ee1894f2b1
Autor:
Carmen De Caro, Federica Raucci, Anella Saviano, Claudia Cristiano, Gian Marco Casillo, Ritamaria Di Lorenzo, Antonia Sacchi, Sonia Laneri, Irene Dini, Simona De Vita, Maria Giovanna Chini, Giuseppe Bifulco, Antonio Calignano, Francesco Maione, Nicola Mascolo
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 126, Iss , Pp 110042- (2020)
Medicinal plants from traditional chinese medicine are used increasingly worldwide for their benefits to health and quality of life for the relevant clinical symptoms related to pain. Among them, Salvia miltiorrhiza Bunge is traditionally used in asi
Externí odkaz:
https://doaj.org/article/bc71af1be6344b4480d5b086cac2a201
Autor:
Anella Saviano, Simona De Vita, Maria Giovanna Chini, Noemi Marigliano, Gianluigi Lauro, Gian Marco Casillo, Federica Raucci, Maria Iorizzi, Robert Klaus Hofstetter, Katrin Fischer, Andreas Koeberle, Oliver Werz, Francesco Maione, Giuseppe Bifulco
Publikováno v:
Biomolecules, Vol 12, Iss 1, p 99 (2022)
Tanshinone IIA (TIIA) and cryptotanshinone (CRY) from Salvia miltiorrhiza Bunge were investigated for their inhibitory activity against the cyclooxygenase-2 (COX-2)/microsomal prostaglandin E synthase-1 (mPGES-1)/endothelial prostaglandin 3 (EP3) pat
Externí odkaz:
https://doaj.org/article/65ca2bf96ba14bbc8206504ddc25ff39
Autor:
Federica Raucci, Asif J. Iqbal, Anella Saviano, Gian Marco Casillo, Marina Russo, Danielle Lezama, Nicola Mascolo, Francesco Maione
Publikováno v:
Data in Brief, Vol 25, Iss , Pp - (2019)
The data supplied in this work are related to the research article entitled “IL-17A neutralizing antibody regulates monosodium urate crystal-induced gouty inflammation” [1]. This data article presents the results of the gating strategy applied to
Externí odkaz:
https://doaj.org/article/1d12c75f29ed4bd3854d3fc120d728a5
Autor:
Anella Saviano, Federica Raucci, Gian Marco Casillo, Chiara Indolfi, Alessia Pernice, Carmen Foreste, Asif Jilani Iqbal, Nicola Mascolo, Francesco Maione
Publikováno v:
Molecules, Vol 25, Iss 24, p 6016 (2020)
Several natural-based compounds and products are reported to possess anti-inflammatory and immunomodulatory activity both in vitro and in vivo. The primary target for these activities is the inhibition of eicosanoid-generating enzymes, including phos
Externí odkaz:
https://doaj.org/article/189f38ce1b1b41709a3a223aad705174
Autor:
Adel Abo Mansour, Mohammed Alfaifi, Anella Saviano, Francesco Maione, Valentina Vellecco, Gian Marco Casillo, Marialuisa Piccolo, Federica Raucci, Elisabetta Panza, Asif J. Iqbal, Carlo Irace, Nicola Mascolo, Maria Grazia Ferraro, Miguel Guerra-Rodriguez, Francesco Caso, Raffaele Scarpa
Publikováno v:
British Journal of Pharmacology. 179:1857-1873
Background and purpose Recent biochemical and pharmacological studies have reported that in several tissues and cell types, microsomal PGE2 synthase (mPGES) and PPAR-γ expression are modulated by a variety of inflammatory factors and stimuli. Consid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47bfd51e16cad524789393c13c550cff
https://doi.org/10.1111/bph.15413
https://doi.org/10.1111/bph.15413
Autor:
Anella Saviano, Federica Raucci, Gian Marco Casillo, Adel Abo Mansour, Vincenzo Piccolo, Camilla Montesano, Martina Smimmo, Valentina Vellecco, Gennaro Capasso, Amedeo Boscaino, Vincenzo Summa, Nicola Mascolo, Asif Jilani Iqbal, Raffaella Sorrentino, Roberta d'Emmanuele di Villa Bianca, Mariarosaria Bucci, Vincenzo Brancaleone, Francesco Maione
In the context of inflammation and immunity, there are fragmented and observational studies relating to the pharmacological activity of Mangifera indica L. and its main active component, mangiferin. Therefore, we aimed to analyze the potential benefi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be60d4ddcfd215aec31ebd8ab36fa416
http://hdl.handle.net/11588/888803
http://hdl.handle.net/11588/888803
