Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gian Franco Sferrazza"'
Autor:
Yervand Eduard Karapetyan, Paula Saá, Sukhvir Paul Mahal, Gian Franco Sferrazza, Alexandra Sherman, Nicole Salès, Charles Weissmann, Corinne Ida Lasmézas
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5730 (2009)
Prion strain identification has been hitherto achieved using time-consuming incubation time determinations in one or more mouse lines and elaborate neuropathological assessment. In the present work, we make a detailed study of the properties of PrP-o
Externí odkaz:
https://doaj.org/article/e8cef4a3c83e4f7aacf804fb91c9b123
Autor:
Corinne Ida Lasmézas, Alicia Faruzzi Brantley, Gian Franco Sferrazza, Gregory Ottenberg, Gavin Rumbaugh, Minghai Zhou, Mohammad Fallahi, Christopher Hubbs
Publikováno v:
Brain. 138:992-1008
The mechanisms of neuronal death in protein misfolding neurodegenerative diseases such as Alzheimer's, Parkinson's and prion diseases are poorly understood. We used a highly toxic misfolded prion protein (TPrP) model to understand neurotoxicity induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b6fb6595f4cdb369442ba1506662c0
https://doi.org/10.1093/brain/awv002
https://doi.org/10.1093/brain/awv002
Autor:
Gian Franco Sferrazza, Gregory Ottenberg, Mohammad Fallahi, Charles Weissmann, Peter Chase, Yervand E. Karapetyan, Timothy P. Spicer, Corinne Ida Lasmézas, Peter Hodder, Minghai Zhou
Publikováno v:
Proceedings of the National Academy of Sciences. 110:7044-7049
Prion diseases such as Creutzfeldt–Jakob disease (CJD) are incurable and rapidly fatal neurodegenerative diseases. Because prion protein (PrP) is necessary for prion replication but dispensable for the host, we developed the PrP–FRET-enabled high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4a0b610279238469730e5a26d34690
https://doi.org/10.1073/pnas.1303510110
https://doi.org/10.1073/pnas.1303510110
Autor:
Jeffrey A. Borgia, Mohammad Al-Ghoul, Gregg B. Fields, Diane Baronas-Lowell, Janelle L. Lauer-Fields, Dmitriy Minond, Gian Franco Sferrazza
Publikováno v:
Journal of Biological Chemistry. 279:43503-43513
Tumor cell binding to components of the basement membrane is well known to trigger intracellular signaling pathways. Signaling ultimately results in the modulation of gene expression, facilitating metastasis. Type IV collagen is the major structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f42ecbbfb73c317b678ecd10970def
https://doi.org/10.1074/jbc.m405979200
https://doi.org/10.1074/jbc.m405979200
Autor:
Gregory Ottenberg, Corinne Ida Lasmézas, Paula Saá, Anja M. Oelschlegel, Gian Franco Sferrazza, Kerri Dorsey
Publikováno v:
Journal of virology. 86(19)
Several lines of evidence suggest that various cofactors may be required for prion replication. PrP binds to polyanions, and RNAs were shown to promote the conversion of PrP C into PrP Sc in vitro . In the present study, we investigated strain-specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a152f1256a0bd87db29ed5c79560a1
https://pubmed.ncbi.nlm.nih.gov/22811520
https://pubmed.ncbi.nlm.nih.gov/22811520
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(8)
Prion diseases are infectious and belong to the group of protein misfolding neurodegenerative diseases. In these diseases, neuronal dysfunction and death are caused by the neuronal toxicity of a particular misfolded form of their cognate protein. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df5cafa026406902a9ea9aa42b574e8
https://pubmed.ncbi.nlm.nih.gov/22323583
https://pubmed.ncbi.nlm.nih.gov/22323583
Autor:
Gian Franco Sferrazza, Xupei Huang, Pingping Jia, Larry F. Lemanski, Dipak K. Dube, Jikui Wang, Gagani Athauda, Mohan P. Achary, Sharon L. Lemanski, Chi Zhang
Publikováno v:
Journal of Biomedical Science, Vol 16, Iss 1, p 81 (2009)
Journal of Biomedical Science
Journal of Biomedical Science
The Mexican axolotl, Ambystoma mexicanum, carries the naturally-occurring recessive mutant gene 'c' that results in a failure of homozygous (c/c) embryos to form hearts that beat because of an absence of organized myofibrils. Our previous studies hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae4075d0062bd49af60051fa4dabe1c
https://doi.org/10.1186/1423-0127-16-81
https://doi.org/10.1186/1423-0127-16-81
Autor:
Gian Franco Sferrazza, Corinne Ida Lasmézas, Paula Saá, Sukhvir P. Mahal, Nicole Salès, Yervand E. Karapetyan, Charles Weissmann, Alexandra Sherman
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5730 (2009)
PLoS ONE
PLoS ONE
Prion strain identification has been hitherto achieved using time-consuming incubation time determinations in one or more mouse lines and elaborate neuropathological assessment. In the present work, we make a detailed study of the properties of PrP-o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d92b20df6402fcf14a91295a0ec0d5
http://europepmc.org/articles/PMC2684634?pdf=render
http://europepmc.org/articles/PMC2684634?pdf=render
Autor:
Chi Zhang, Syamalima Dube, Howard Prentice, Elena Rueda-de-Leon, Kristine Halager, Gian Franco Sferrazza, Xupei Huang, Amit Gupta, Pingping Jia, Gagani Athauda, Dipak K. Dube, Larry F. Lemanski, Jennifer A. Maier, Sharon L. Lemanski, Alyssa K. Stassi
The Mexican axolotl, Ambystoma mexicanum, has been a useful animal model to study heart development and cardiac myofibrillogenesis. A naturally-occurring recessive mutant, gene "c", for cardiac non-function in the Mexican axolotl causes a failure of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a5740a1a43d142620955bdd50235d9
https://europepmc.org/articles/PMC2034438/
https://europepmc.org/articles/PMC2034438/
