Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Gian Cesare Tron"'
Autor:
Rolando Cannalire, Federica Santoro, Camilla Russo, Giulia Graziani, Gian Cesare Tron, Alfonso Carotenuto, Diego Brancaccio, Mariateresa Giustiniano
Publikováno v:
ACS Organic & Inorganic Au, Vol 2, Iss 1, Pp 66-74 (2021)
Externí odkaz:
https://doaj.org/article/81cc00474ab340e7b19079186fa61bcd
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 1335-1351 (2021)
Organic chemistry honors Icilio Guareschi (1847–1918) with three eponymic reactions, the best known ones being the Guareschi synthesis of pyridones and the Guareschi–Lustgarten reaction. A third Guareschi reaction, the so-called “Guareschi 1897
Externí odkaz:
https://doaj.org/article/3ae24eaa3a7a4817825309f4a0fe842d
Autor:
Suresh Velnati, Alberto Massarotti, Annamaria Antona, Maria Talmon, Luigia Grazia Fresu, Alessandra Silvia Galetto, Daniela Capello, Alessandra Bertoni, Valentina Mercalli, Andrea Graziani, Gian Cesare Tron, Gianluca Baldanzi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 96-108 (2020)
A series of analogues of Amb639752, a novel diacylglycerol kinase (DGK) inhibitor recently discovered by us via virtual screening, have been tested. The compounds were evaluated as DGK inhibitors on α, θ, and ζ isoforms, and as antagonists on sero
Externí odkaz:
https://doaj.org/article/3339702823c34737b631d4896dd549e8
Autor:
Artemiy Nichugovskiy, Varvara Maksimova, Ekaterina Trapeznikova, Elizaveta Eshtukova-Shcheglova, Igor Ivanov, Marianna Yakubovskaya, Kirill Kirsanov, Dmitry Cheshkov, Gian Cesare Tron, Mikhail Maslov
Publikováno v:
Molecules, Vol 27, Iss 19, p 6218 (2022)
Natural polyamines (PAs) are involved in the processes of proliferation and differentiation of cancer cells. Lipophilic synthetic polyamines (LPAs) induce the cell death of various cancer cell lines. In the current paper, we have demonstrated a new m
Externí odkaz:
https://doaj.org/article/7e2b58fcfbd747c5a29687d748becc48
Autor:
Ubaldina Galli, Giorgia Colombo, Cristina Travelli, Gian Cesare Tron, Armando A. Genazzani, Ambra A. Grolla
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Nicotinamide adenine dinucleotide (NAD) is a cofactor of many enzymatic reactions as well as being a substrate for a number of NAD-consuming enzymes (e.g., PARPS, sirtuins, etc). NAD can be synthesized de novo starting from tryptophan, nicotinamide,
Externí odkaz:
https://doaj.org/article/533060d51ac24f429b4a5ccc95a3118e
Autor:
Carlo C. Campa, Rangel L. Silva, Jean P. Margaria, Tracey Pirali, Matheus S. Mattos, Lucas R. Kraemer, Diego C. Reis, Giorgio Grosa, Francesca Copperi, Eduardo M. Dalmarco, Roberto C. P. Lima-Júnior, Silvio Aprile, Valentina Sala, Federica Dal Bello, Douglas Silva Prado, Jose Carlos Alves-Filho, Claudio Medana, Geovanni D. Cassali, Gian Cesare Tron, Mauro M. Teixeira, Elisa Ciraolo, Remo C. Russo, Emilio Hirsch
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Activation of PI3K plays a role in pulmonary inflammation. Here, the authors develop a drug inhibitor of PI3K, and show that it inhibits lung inflammation and damage in mouse models of asthma and lung fibrosis.
Externí odkaz:
https://doaj.org/article/ffd766e4bb69453a8c45e742f2d6dd75
Publikováno v:
Molecules, Vol 26, Iss 21, p 6579 (2021)
Biogenic polyamines (PAs) are involved in the growth and development of normal cells, and their intracellular concentration is stable. The concentration of PAs in cancer cells is significantly increased to promote and sustain their rapid proliferatio
Externí odkaz:
https://doaj.org/article/414c51bcd7124ffd8c640ef76c522c66
Autor:
Rolando Cannalire, Camilla Russo, Paolo Luciano, Bruno Cerra, Antimo Gioiello, Francesca Brunelli, Gian Cesare Tron, Mariateresa Giustiniano
Publikováno v:
Molecular Diversity. 27:511-515
A new Lewis acid promoted domino isocyanide insertion/5-exo-dig cyclization of readily available Strecker 3-component adducts to 4-substituted 5-aminoimidazole derivatives is herein reported. Despite their potential as relevant heterocyclic scaffolds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b702aaa42832776da0324c7d3728d31a
https://doi.org/10.1007/s11030-022-10418-4
https://doi.org/10.1007/s11030-022-10418-4
Publikováno v:
Molecules, Vol 26, Iss 3, p 558 (2021)
Despite its uniqueness, the Bargellini multicomponent reaction remains barely known by the most part of chemists. This can be ascribed to the fact that this transformation has not been adequately reviewed in the classic books of named reactions in or
Externí odkaz:
https://doaj.org/article/46ab1a9e1a304e5d9a09869adeb1f9e0
Publikováno v:
Green Chemistry. 24:3993-4003
The direct photoexcitation of isocyanides is able to trigger a collection of Ugi-like multicomponent reactions under metal-free conditions and in the absence of any additives starting from both linear and cyclic tertiary aromatic amines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb592d6e804113dffe7169e3364d7187
https://doi.org/10.1039/d2gc00855f
https://doi.org/10.1039/d2gc00855f