Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gian Carlo G. Parico"'
Autor:
Gian Carlo G. Parico, Carrie L. Partch
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-9 (2020)
Abstract Cryptochrome (CRY) proteins play an essential role in regulating mammalian circadian rhythms. CRY is composed of a structured N-terminal domain known as the photolyase homology region (PHR), which is tethered to an intrinsically disordered C
Externí odkaz:
https://doaj.org/article/c8e79cee5afc486ea4445ffad71eb9e2
Autor:
Priya Crosby, Nicolette F. Goularte, Diksha Sharma, Eefei Chen, Gian Carlo G. Parico, Jon M. Philpott, Rachel Harold, Chelsea L. Gustafson, Carrie L. Partch
The mammalian protein CHRONO was previously identified to be a rhythmically expressed repressor of the circadian transcriptional activator complex CLOCK:BMAL1. Mice and cells lacking CHRONO display a lengthened circadian period and altered circadian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee034951910a7b04247afc6a3278ef65
https://doi.org/10.1101/2022.10.04.510902
https://doi.org/10.1101/2022.10.04.510902
Autor:
Katja A. Lamia, Gian Carlo G. Parico, Michael J. Bollong, Alanna B. Chan, Carrie L. Partch, Jennifer L. Fribourgh, Lara Ibrahim
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 27
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Disruption of circadian rhythms increases the risk of several types of cancer. Mammalian cryptochromes (CRY1 and CRY2) are circadian transcriptional repressors that are related to DNA repair enzymes. While CRYs lack DNA repair activity, they modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eadc89159164f19472defcc92798b31d
https://escholarship.org/uc/item/1zk672h1
https://escholarship.org/uc/item/1zk672h1
Autor:
Carrie L. Partch, Gian Carlo G. Parico
Publikováno v:
Cell communication and signaling : CCS, vol 18, iss 1
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-9 (2020)
Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-9 (2020)
Cell Communication and Signaling : CCS
Cryptochrome (CRY) proteins play an essential role in regulating mammalian circadian rhythms. CRY is composed of a structured N-terminal domain known as the photolyase homology region (PHR), which is tethered to an intrinsically disordered C-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00057b75e1521a27f4f6af0af0cb025
https://escholarship.org/uc/item/9242731k
https://escholarship.org/uc/item/9242731k
Autor:
Hsiau-Wei Lee, Carrie L. Partch, Jennifer L. Fribourgh, Gian Carlo G. Parico, Britney N. Hernandez, Ivette Perez
Publikováno v:
Proc Natl Acad Sci U S A
Circadian rhythms are generated by interlocked transcription-translation feedback loops that establish cell-autonomous biological timing of ∼24 h. Mutations in core clock genes that alter their stability or affinity for one another lead to changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc40024fc71388ae2e24a1a3e6e3a457
https://pubmed.ncbi.nlm.nih.gov/33106415
https://pubmed.ncbi.nlm.nih.gov/33106415
Autor:
Alicia K. Michael, Ning Zheng, Christin Rakers, Leslee T. Nguyen, Gian Carlo G. Parico, Jennifer L. Fribourgh, Ashutosh Srivastava, Colby R. Sandate, Carrie L. Partch, Megan R. Torgrimson, Peter L. Hsu, Florence Tama, Gabriel C. Lander, Tsuyoshi Hirota, Sarvind Tripathi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01609627de930a3a99ed9419ce67d8c7
https://doi.org/10.7554/elife.55275.sa2
https://doi.org/10.7554/elife.55275.sa2
Autor:
Carrie L. Partch, Jennifer L. Fribourgh, Ivette Perez, Britney N. Hernandez, Hsiau-Wei Lee, Gian Carlo G. Parico
Circadian rhythms are generated by a transcription-translation feedback loop that establishes cell-autonomous biological timing of ~24-hours. A prevalent human variation in the core clock gene cryptochrome 1, Cry1Δ11, lengthens circadian period to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809d38bd0f4b00d933faf8b37b7c0c90
Autor:
Leslee T. Nguyen, Alicia K. Michael, Ning Zheng, Peter L. Hsu, Megan R. Torgrimson, Florence Tama, Gian Carlo G. Parico, Christin Rakers, Gabriel C. Lander, Ashutosh Srivastava, Colby R. Sandate, Carrie L. Partch, Jennifer L. Fribourgh, Sarvind Tripathi, Tsuyoshi Hirota
SummaryCircadian rhythms are generated by a transcription-based feedback loop where CLOCK:BMAL1 drive transcription of their repressors (PER1/2, CRY1/2), which bind to CLOCK:BMAL1 to close the feedback loop with ~24-hour periodicity. Here we identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e71620c8dc84db37b2a3ddc04d5eab
https://doi.org/10.1101/740464
https://doi.org/10.1101/740464
Publikováno v:
Biophysical Journal. 114:570a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e33267afe96df6920154d05b69bcddc5
https://doi.org/10.1016/j.bpj.2017.11.3116
https://doi.org/10.1016/j.bpj.2017.11.3116
Autor:
Jennifer L Fribourgh, Ashutosh Srivastava, Colby R Sandate, Alicia K Michael, Peter L Hsu, Christin Rakers, Leslee T Nguyen, Megan R Torgrimson, Gian Carlo G Parico, Sarvind Tripathi, Ning Zheng, Gabriel C Lander, Tsuyoshi Hirota, Florence Tama, Carrie L Partch
Publikováno v:
eLife, Vol 9 (2020)
Mammalian circadian rhythms are generated by a transcription-based feedback loop in which CLOCK:BMAL1 drives transcription of its repressors (PER1/2, CRY1/2), which ultimately interact with CLOCK:BMAL1 to close the feedback loop with ~24 hr periodici
Externí odkaz:
https://doaj.org/article/fea51974e20a400a90ed8488c058c791