Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Giampiero Mei"'
Autor:
Giovanna Di Nardo, Almerinda Di Venere, Chao Zhang, Eleonora Nicolai, Silvia Castrignanò, Luisa Di Paola, Gianfranco Gilardi, Giampiero Mei
Publikováno v:
Biology Direct, Vol 16, Iss 1, Pp 1-12 (2021)
Abstract Human aromatase is a member of the cytochrome P450 superfamily, involved in steroid hormones biosynthesis. In particular, it converts androgen into estrogens being therefore responsible for the correct sex steroids balance. Due to its capaci
Externí odkaz:
https://doaj.org/article/b195a47b31ca48eba9dac091316f4dda
Publikováno v:
Symmetry, Vol 14, Iss 4, p 720 (2022)
TNF Receptor-Associated Factor 2 (TRAF2) is a homo-trimer belonging to the TNF-receptor-associated factor family (TRAFs). The TRAF2 oligomeric state is crucial for receptor binding, the interaction with other proteins (involved in the TNFR signaling)
Externí odkaz:
https://doaj.org/article/061f7d714732422c84be9eb24818dd80
Autor:
Eleonora Nicolai, Velia Minicozzi, Luisa Di Paola, Rosaria Medda, Francesca Pintus, Giampiero Mei, Almerinda Di Venere
Publikováno v:
Symmetry, Vol 14, Iss 3, p 522 (2022)
Symmetry is an intrinsic property of homo-oligomers. Amine oxidases are multidomain homodimeric enzymes that contain one catalytic site per subunit, and that share a high homology degree. In this paper, we investigated, by fluorescence spectroscopy m
Externí odkaz:
https://doaj.org/article/0847187a054145df8b2301c10c5c5fab
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64840 (2013)
In this work, we used a combination of fluorescence correlation spectroscopy (FCS) and molecular dynamics (MD) simulation methodologies to acquire structural information on pH-induced unfolding of the maltotriose-binding protein from Thermus thermoph
Externí odkaz:
https://doaj.org/article/8829d58fcd1240e5af8a1575ea68d8d0
Autor:
Giovanna Di Nardo, Maximilian Breitner, Sheila J Sadeghi, Silvia Castrignanò, Giampiero Mei, Almerinda Di Venere, Eleonora Nicolai, Paola Allegra, Gianfranco Gilardi
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82118 (2013)
Human aromatase (CYP19A1) is a steroidogenic cytochrome P450 converting androgens into estrogens. No ligand-free crystal structure of the enzyme is available to date. The crystal structure in complex with the substrate androstenedione and the steroid
Externí odkaz:
https://doaj.org/article/39667380175d44a1aec1fd663af13f11
Autor:
Eleonora Nicolai, Anna Maria Caccuri, Almerinda Di Venere, Velia Minicozzi, Giampiero Mei, Luisa Di Paola
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 5871, p 5871 (2021)
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 5871, p 5871 (2021)
TNF Receptor Associated Factor 2 (TRAF2) is a trimeric protein that belongs to the TNF receptor associated factor family (TRAFs). The TRAF2 oligomeric state is crucial for receptor binding and for its interaction with other proteins involved in the T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c9d8ef86494d59b60f3153916120b6
http://europepmc.org/articles/PMC8198530
http://europepmc.org/articles/PMC8198530
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611531
In this paper we report a procedure to analyze protein homodimer interfaces.We approached the problem by means of a topological methodology. In particular, we analyzed the subunits interface of about 50 homodimers and we have defined a few parameters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f53281e5c7909705bffe3d5aaba31e3
http://hdl.handle.net/2108/298857
http://hdl.handle.net/2108/298857
Autor:
Eleonora Nicolai, Silvia Castrignanò, Gianfranco Gilardi, Chao Zhang, Giampiero Mei, Giovanna Di Nardo, Almerinda Di Venere, Luisa Di Paola
Publikováno v:
Biology Direct
Biology Direct, Vol 16, Iss 1, Pp 1-12 (2021)
Biology Direct, Vol 16, Iss 1, Pp 1-12 (2021)
Human aromatase is a member of the cytochrome P450 superfamily, involved in steroid hormones biosynthesis. In particular, it converts androgen into estrogens being therefore responsible for the correct sex steroids balance. Due to its capacity in pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f360fb2dfb3f59d659d47d20cf597f49
http://hdl.handle.net/2108/294317
http://hdl.handle.net/2108/294317
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611531
Proteins are located in the twilight zone between chemistry and biology, where a peculiar kind of complexity starts. Proteins are the smallest 'devices' showing a sensible adaptation to their environment by the production of appropriate behavior when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28ec7a46d80aa26d8af46b8fc71c809
http://hdl.handle.net/2108/298855
http://hdl.handle.net/2108/298855
Autor:
Alessandro Finazzi Agrò, Giampiero Mei
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611531
The discovery of hemoglobin allosteric properties is briefly summarized and contextualized in the frame of the main biochemical revelations that characterized the first half of the XX century. In particular, the historical background of DNA, RNA, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8767b7af0690a51bf4da2abda7ead058
https://doi.org/10.1007/978-1-0716-1154-8_1
https://doi.org/10.1007/978-1-0716-1154-8_1