Biotelemetric Monitoring of Brain Neurochemistry in Conscious Rats Using Microsensors and Biosensors

Autor: Maria S. Desole, Robert D. O’Neill, John P. Lowry, Vittorio Mazzarello, Gianfranco Bazzu, Ylenia Spissu, Giulia Puggioni, Rossana Migheli, Gaia Rocchitta, Giammario Calia, Pier A. Serra

Publikováno v: Sensors, Vol 9, Iss 4, Pp 2511-2523 (2009)

In this study we present the real-time monitoring of three key brain neurochemical species in conscious rats using implantable amperometric electrodes interfaced to a biotelemetric device. The new system, derived from a previous design, was coupled w

Externí odkaz: https://doaj.org/article/78cb6ee46c294faa8520a77bbe124c23

Electropolymerized phenol derivatives as permselective polymers for biosensor applications

Autor: Samir Jaoua, Davide Fabbri, Robert D. O'Neill, Salvatore Marceddu, Patrizia Monti, Giammario Calia, Giovanna Delogu, Pier Andrea Serra, Maria Antonietta Dettori, Quirico Migheli

Publikováno v: Analyst (Lond., 1877, Online) 140 (2015): 3607–3615. doi:10.1039/c5an00363f
info:cnr-pdr/source/autori:Calia, Giammario; Monti, Patrizia; Marceddu, Salvatore; Dettori, Maria A.; Fabbri, Davide; Jaoua, Samir; O'Neill, Robert D.; Serra, Pier A.; Delogu, Giovanna; Migheli, Quirico/titolo:Electropolymerized phenol derivatives as permselective polymers for biosensor application./doi:10.1039%2Fc5an00363f/rivista:Analyst (Lond., 1877, Online)/anno:2015/pagina_da:3607/pagina_a:3615/intervallo_pagine:3607–3615/volume:140

Amperometric biosensors are often coated with a polymeric permselective film to avoid electroactive interference by reducing agents present in the target medium. Phenylenediamine and phenol monomers are commonly used to form these permselective films

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3585450878a9364f7729ce648c3c8455
https://doi.org/10.1039/c5an00363f

Low electro-synthesis potentials improve permselectivity of polymerized natural phenols in biosensor applications

Autor: Samir Jaoua, Quirico Migheli, Robert D. O'Neill, Salvatore Marceddu, Davide Fabbri, Patrizia Monti, Giovanna Delogu, Maria Antonietta Dettori, Pier Andrea Serra, Giammario Calia

Publikováno v: Talanta (Oxf.) 162 (2016): 151–158. doi:10.1016/j.talanta.2016.10.019
info:cnr-pdr/source/autori:a-c)Patrizia Monti, a-b)Giammario Calia, d)Salvatore Marceddu, c)Maria A. Dettori, c)Davide Fabbri, e)Samir Jaoua, f)Robert D. O'Neill, a)Quirico Migheli, c)Giovanna Delogu, b)Pier A. Serra,/titolo:Low electro-synthesis potentials improve permselectivity of polymerized natural phenols in biosensor applications/doi:10.1016%2Fj.talanta.2016.10.019/rivista:Talanta (Oxf.)/anno:2016/pagina_da:151/pagina_a:158/intervallo_pagine:151–158/volume:162

First-generation amperometric biosensors are often based on the electro-oxidation of oxidase-generated H2O2. At the applied potential used in most studies, other molecules such as ascorbic acid or dopamine can be oxidized. Phenylenediamines are commo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86b17484a45892c8f8ee38ff70f95c7
https://publications.cnr.it/doc/359247

Real-Time Monitoring of Brain Tissue Oxygen Using a Miniaturized Biotelemetric Device Implanted in Freely Moving Rats

Autor: Gianfranco Bazzu, Giulia Maria Grazia Puggioni, R Migheli, John P. Lowry, Robert D. O’Neill, Pier Andrea Serra, Gaia Giovanna Maria Rocchitta, Maria Speranza Desole, Sonia Dedola, Giammario Calia

Publikováno v: Analytical Chemistry. 81:2235-2241

A miniaturized biotelemetric device for the amperometric detection of brain tissue oxygen is presented. The new system, derived from a previous design, has been coupled with a carbon microsensor for the real-time detection of dissolved O(2) in the st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34604b16564b541872f98a265caab57
https://doi.org/10.1021/ac802390f

Simultaneous telemetric monitoring of brain glucose and lactate and motion in freely moving rats

Autor: Maria Speranza Desole, Gaia Giovanna Maria Rocchitta, Pier Andrea Serra, Giammario Calia, Robert D. O'Neill, Rossana Migheli, Donatella Farina, Gianfranco Bazzu, Ottavio Secchi, Maria Domenica Alvau

Publikováno v: Analytical chemistry. 85(21)

A new telemetry system for simultaneous detection of extracellular brain glucose and lactate and motion is presented. The device consists of dual-channel, single-supply miniature potentiostat–I/V converter, a microcontroller unit, a signal transmit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d1208599702e61ced1693c776dd822c
https://pubmed.ncbi.nlm.nih.gov/24102201