Effects of Cisplatin in Neuroblastoma Rat Cells: Damage to Cellular Organelles

Autor: Giada Santin, Luigi Scietti, Paola Veneroni, Sergio Barni, Graziella Bernocchi, Maria Grazia Bottone

Publikováno v: International Journal of Cell Biology, Vol 2012 (2012)

Cisplatin (cisPt) is a chemotherapy agent used as a treatment for several types of cancer. The main cytotoxic effect of cisplatin is generally accepted to be DNA damage. Recently, the mechanism by which cisPt generates the cascade of events involved

Externí odkaz: https://doaj.org/article/81918fc65c014e67b5a632c130c05250

Regulated forms of cell death are induced by the photodynamic action of the fluorogenic substrate, Hypocrellin B-acetate

Autor: Carlo Pellicciari, Giada Santin, Manuela Malatesta, Maria Grazia Bottone, Giovanni Bottiroli, Anna Ivana Scovassi, Anna Cleta Croce

Publikováno v: Journal of Photochemistry and Photobiology B: Biology. 125:90-97

The addition of chemical groups to a photosensitizer makes it to act as a fluorogenic substrate, increasing its ability to enter the cells. In this work, the cytotoxic efficacy of Hypocrellin B modified by addition of two acetate groups (HypB-Ac) was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6e5a329c236cbcd38927c7c3664656
https://doi.org/10.1016/j.jphotobiol.2013.05.006

Bilirubin: an autofluorescence bile biomarker for liver functionality monitoring

Autor: Mariapia Vairetti, Anna Cleta Croce, Giovanni Bottiroli, Andrea Ferrigno, Giada Santin

Publikováno v: Journal of Biophotonics. 7:810-817

Excitation at 366-465 nm of bilirubin in aqueous solution with solubilizing agents results in emission spectra composed by two main bands. The variation of their relative contributions as shown by changes in the spectral shape are consistent with the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2bc96ad1ce4d848d5bcf58195c80b178
https://doi.org/10.1002/jbio.201300039

Resveratrol-procyanidin blend: nutraceutical and antiaging efficacy evaluated in a placebo-controlled, double-blind study

Autor: Pedro Tocabens, Daniela Buonocore, Maria Grazia Bottone, Enza Cestone, Vincenzo Nobile, Fulvio Marzatico, Giada Santin, Angelo Lazzeretti

Publikováno v: Clinical, Cosmetic and Investigational Dermatology, Vol 2012, Iss default, Pp 159-165 (2012)
Clinical, Cosmetic and Investigational Dermatology

Daniela Buonocore,1 Angelo Lazzeretti,2 Pedro Tocabens,3 Vincenzo Nobile,4 Enza Cestone,4 Giada Santin,5 Maria G Bottone,5,6 Fulvio Marzatico11Laboratory of Pharmacobiochemistry, Nutrition and Nutraceutical of Wellness, Department of Biology and Biot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92fcfc3ef2cde83f228a9e24389db690
http://www.dovepress.com/resveratrol-procyanidin-blend-nutraceutical-and-antiaging-efficacy-eva-a11183

[Pt(O,O'-acac)(γ-acac)(DMS)] versus cisplatin: apoptotic effects in B50 neuroblastoma cells

Autor: Veronica Dal Bo, Violetta Insolia, Maria Grazia Bottone, Sergio Barni, Paola Veneroni, Graziella Bernocchi, Francesco Paolo Fanizzi, Maddalena Grimaldi, Manuela Verri, Valeria Maria Piccolini, Sandra Angelica De Pascali, Giada Santin

Publikováno v: Histochemistry and cell biology. 145(5)

Cisplatin is one of the most active chemotherapeutic agents used in the treatment of childhood and adult malignancies. Cisplatin induces cell death through different pathways. Despite its effectiveness, the continued clinical use of cisplatin is limi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13583f8819cba654ae19fec036fd8bd2
https://pubmed.ncbi.nlm.nih.gov/26748644