Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Giada, Frascaroli"'
Publikováno v:
Viruses, Vol 15, Iss 4, p 979 (2023)
Viruses can induce the fusion of infected and neighboring cells, leading to the formation of syncytia. Cell–cell fusion is mediated by viral fusion proteins on the plasma membrane of infected cells that interact with cellular receptors on neighbori
Externí odkaz:
https://doaj.org/article/a234a7853cce4f8e98921a30718172ba
Autor:
Enrico Caragliano, Stefano Bonazza, Giada Frascaroli, Jiajia Tang, Timothy K. Soh, Kay Grünewald, Jens B. Bosse, Wolfram Brune
Publikováno v:
Cell Reports, Vol 38, Iss 10, Pp 110469- (2022)
Summary: Human cytomegalovirus (HCMV) replicates its DNA genome in specialized replication compartments (RCs) in the host cell nucleus. These membrane-less organelles originate as spherical structures and grow in size over time. However, the mechanis
Externí odkaz:
https://doaj.org/article/19f814b0feb24c2395020321e8b28f80
Autor:
Ann-Christin Tallarek, Christopher Urbschat, Luis Fonseca Brito, Stephanie Stanelle-Bertram, Susanne Krasemann, Giada Frascaroli, Kristin Thiele, Agnes Wieczorek, Nadine Felber, Marc Lütgehetmann, Udo R. Markert, Kurt Hecher, Wolfram Brune, Felix Stahl, Gülsah Gabriel, Anke Diemert, Petra Clara Arck
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Pregnant women have been carefully observed during the COVID-19 pandemic, as the pregnancy-specific immune adaptation is known to increase the risk for infections. Recent evidence indicates that even though most pregnant have a mild or asymptomatic c
Externí odkaz:
https://doaj.org/article/97c2554c8b154c33b749bebc61c60812
Autor:
Olha Puhach, Eleonore Ostermann, Christoph Krisp, Giada Frascaroli, Hartmut Schlüter, Melanie M Brinkmann, Wolfram Brune
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008546 (2020)
Cytomegaloviruses (CMV) infect many different cell types and tissues in their respective hosts. Monocytes and macrophages play an important role in CMV dissemination from the site of infection to target organs. Moreover, macrophages are specialized i
Externí odkaz:
https://doaj.org/article/32fea7ee70464e67b2841c41926b4a70
Autor:
Giada Frascaroli, Giada Rossini, Virginia Maltoni, Michele Bartoletti, Patrizia Ortolani, Sara Gredmark-Russ, Francesco Gelsomino, Alessandra Moroni, Silvia Silenzi, Gastone Castellani, Vittorio Sambri, Antonio Mastroianni, Wolfram Brune, Stefania Varani
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Background: Human cytomegalovirus (CMV) modulates both innate and adaptive immune responses. However, limited data are available on the role of receptors of innate immunity, such as toll-like receptors (TLRs) in contributing to antiviral responses an
Externí odkaz:
https://doaj.org/article/8f1cd321593140f2ab8718b512039348
Publikováno v:
Viruses, Vol 13, Iss 11, p 2134 (2021)
Viral infection activates cellular antiviral defenses including programmed cell death (PCD). Many viruses, particularly those of the Herpesviridae family, encode cell death inhibitors that antagonize different forms of PCD. While some viral inhibitor
Externí odkaz:
https://doaj.org/article/78a69bb246cd4b8da573c3db788e7c44
Publikováno v:
Viruses, Vol 13, Iss 10, p 1973 (2021)
Cell–cell fusion is a fundamental and complex process that occurs during reproduction, organ and tissue growth, cancer metastasis, immune response, and infection. All enveloped viruses express one or more proteins that drive the fusion of the viral
Externí odkaz:
https://doaj.org/article/f7741a7b05b84a32a76aec879ced92ea
Autor:
Giada Frascaroli, Carina Lecher, Stefania Varani, Corinna Setz, Johannes van der Merwe, Wolfram Brune, Thomas Mertens
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Human cytomegalovirus (HCMV) persistently infects 40–90% of the human population but in the face of a normal immune system, viral spread and dissemination are efficiently controlled thus preventing clinically signs and disease. HCMV-infected hosts
Externí odkaz:
https://doaj.org/article/ac5e03ddaeea452fa77b5fd00e05ebdc
Autor:
Sarah Zobel, Mechthild Lorenz, Giada Frascaroli, Janik Böhnke, Nicole C. Bilz, Megan L. Stanifer, Steeve Boulant, Sandra Bergs, Uwe G. Liebert, Claudia Claus
Publikováno v:
Viruses, Vol 10, Iss 10, p 540 (2018)
Rubella virus (RV) infection impacts cellular metabolic activity in a complex manner with strain-specific nutritional requirements. Here we addressed whether this differential metabolic influence was associated with differences in oxidative stress in
Externí odkaz:
https://doaj.org/article/30bd8381c0e743c79731e87bc58d68ac
Publikováno v:
Viruses
Viruses, Vol 13, Iss 2134, p 2134 (2021)
Volume 13
Issue 11
Viruses, Vol 13, Iss 2134, p 2134 (2021)
Volume 13
Issue 11
Viral infection activates cellular antiviral defenses including programmed cell death (PCD). Many viruses, particularly those of the Herpesviridae family, encode cell death inhibitors that antagonize different forms of PCD. While some viral inhibitor