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pro vyhledávání: '"Giacomo Paonessaw"'
Autor:
Neil C. Rogers, Mark S. Burfoot, Morris F. White, Sandra Pellegrini, Jon M. Smith, Sebastian Pons, Diane Watling, Ian M. Kerr, Giacomo Paonessaw
Publikováno v:
The Journal of biological chemistry. 272(39)
In addition to a role in response to insulin and insulin-like growth factors, insulin receptor substrate 1 (IRS-1) is phosphorylated in response to IL-4, the interferons (IFNs) and oncostatin M (OSM). Here mutant cell lines lacking JAK1, JAK2, or Tyk