Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Giacomo E. M. Crisenza"'
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-4 (2020)
Can organic chemistry mimic nature in efficiency and sustainability? Not yet, but recent developments in photoredox catalysis animated the synthetic chemistry field, providing greener opportunities for industry and academia.
Externí odkaz:
https://doaj.org/article/38fdd6f918c44681b7df9e79433b282d
Autor:
Soumitra Agasti, Frédéric Beltran, Emma Pye, Nikolas Kaltsoyannis, Giacomo E. M. Crisenza, David J. Procter
Publikováno v:
Nature Chemistry. 15:535-541
C(sp3)-rich bicyclic hydrocarbon scaffolds, as exemplified by bicyclo[1.1.1]pentanes (BCPs), play an increasingly high-profile role as saturated bioisosteres of benzenoids in medicinal chemistry and crop science. Substituted bicyclo[2.1.1]hexanes (BC
Autor:
Abhishek Dewanji, Leendert van Dalsen, James A. Rossi-Ashton, Eloise Gasson, Giacomo E. M. Crisenza, David J. Procter
Publikováno v:
Nature Chemistry. 15:43-52
Autor:
Ranjana Bisht, Mihai V. Popescu, Zhen He, Ameer M. Ibrahim, Giacomo E. M. Crisenza, Robert S. Paton, David J. Procter
Publikováno v:
Angewandte Chemie.
Autor:
Charlotte Morrill, Áron Péter, Ilma Amalina, Emma Pye, Giacomo E. M. Crisenza, Nikolas Kaltsoyannis, David J. Procter
Publikováno v:
Morrill, C, Péter, Á, Amalina, I, Pye, E, Crisenza, G, Kaltsoyannis, N & Procter, D 2022, ' Diastereoselective radical 1,4-ester migration: radical cyclizations of acyclic esters with SmI2 ', Journal of the American Chemical Society, vol. 144, no. 30, pp. 13946-13952 . https://doi.org/10.1021/jacs.2c05972
Reductive cyclizations of carbonyl compounds, mediated by samarium(II) diiodide (SmI2, Kagan’s reagent), represent an invaluable platform to generate molecular complexity in a stereocontrolled manner. In addition to classical ketone and aldehyde su
Autor:
Oliver J. Knowles, Linus O. Johannissen, Giacomo E. M. Crisenza, Sam Hay, David Leys, David J. Procter
Publikováno v:
Knowles, O J, Johannissen, L O, Crisenza, G E M, Hay, S, Leys, D & Procter, D J 2022, ' A Vitamin B2-Photocatalysed Approach to Methionine Analogues ', Angewandte Chemie. International Edition, vol. 61, no. 50 . https://doi.org/10.1002/anie.202212158
Access to new non-canonical amino acid residues is crucial for medicinal chemistry and chemical biology. Analogues of the amino acid methionine have been far less explored—despite their use in biochemistry, pharmacology and peptide bioconjugation.
Autor:
Oliver J, Knowles, Linus O, Johannissen, Giacomo E M, Crisenza, Sam, Hay, David, Leys, David J, Procter
Publikováno v:
Angewandte Chemie (International ed. in English). 61(50)
Access to new non-canonical amino acid residues is crucial for medicinal chemistry and chemical biology. Analogues of the amino acid methionine have been far less explored-despite their use in biochemistry, pharmacology and peptide bioconjugation. Th
Autor:
Adriana Faraone, Paolo Melchiorre, Daniele Mazzarella, Giacomo E. M. Crisenza, Eugenio Gandolfo
Publikováno v:
Nature Chemistry
Enantioselective catalytic processes are promoted by chiral catalysts that can execute a specific mode of catalytic reactivity, channeling the chemical reaction through a certain mechanistic pathway. Here, we show how by simply using visible light we
Autor:
Chunling Shi, Srimanta Manna, David J. Procter, Watcharapon Prasitwatcharakorn, Quentin Dherbassy, Gregory J. P. Perry, Giacomo E. M. Crisenza
Publikováno v:
Angewandte Chemie (International Ed. in English)
Quinazolinones are common substructures in molecules of medicinal importance. We report an enantioselective copper‐catalyzed borylative cyclization for the assembly of privileged pyrroloquinazolinone motifs. The reaction proceeds with high enantio
Autor:
Abhishek, Dewanji, Leendert, van Dalsen, James A, Rossi-Ashton, Eloise, Gasson, Giacomo E M, Crisenza, David J, Procter
Publikováno v:
Nature chemistry.
The photoactivation of electron donor-acceptor complexes has emerged as a sustainable, selective and versatile strategy for the generation of radical species. However, when it comes to aryl radical formation, this strategy remains hamstrung by the el