Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Giacomo Diaceri"'
Autor:
Jean-François Franetich, Sachiko Hirosue, Maria A. S. Broggi, Giacomo Diaceri, Melody A. Swartz, Xavier Quaglia-Thermes, Marcin Kwissa, Jeffrey A. Hubbell, Dominique Mazier, Leonardo Bonilla-Ramirez, Laura Jeanbart, D. Scott Wilson, Ruyi Wang, Michal M. Raczy
Publikováno v:
Nature Materials. 18:175-185
Fully effective vaccines for complex infections must elicit a diverse repertoire of antibodies (humoral immunity) and CD8+ T-cell responses (cellular immunity). Here, we present a synthetic glyco-adjuvant named p(Man–TLR7), which, when conjugated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee076d94a592abcf84502db63df7467
https://doi.org/10.1038/s41563-018-0256-5
https://doi.org/10.1038/s41563-018-0256-5
Autor:
Jeffrey A. Hubbell, D. Scott Wilson, Brunggel Kym, Xavier Quaglia-Thermes, Sachiko Hirosue, Giacomo Diaceri, Martina Damo, Michal M. Raczy
Publikováno v:
Nature biomedical engineering. 3(10)
Homeostatic antigen presentation by hepatic antigen-presenting cells, which results in tolerogenic T-cell education, could be exploited to induce antigen-specific immunological tolerance. Here we show that antigens modified with polymeric forms of ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c10cbef9c1fd110a08391d928190f9f4
https://pubmed.ncbi.nlm.nih.gov/31358881
https://pubmed.ncbi.nlm.nih.gov/31358881
Our group has recently shown induction of antigen-specific T cell tolerance through targeting of the antigen to erythrocytes in situ. The tolerogenic state is characterized by initial proliferation of antigen-specific T cells and subsequent acquisiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d298c10228eb507c62a0eb59ffe756
https://doi.org/10.1101/278457
https://doi.org/10.1101/278457
Autor:
David Baud, P. Hohlfeld, Yvan Vial, Giacomo Diaceri, Jean-François Tolsa, F. Delhaes, Anne-Christine Peyter, Steeve Menétrey
Publikováno v:
Placenta
Introduction Intrauterine growth restriction (IUGR) affects ∼8% of all pregnancies and is associated with major perinatal mortality and morbidity, and with an increased risk to develop cardiovascular diseases in adulthood. Despite identification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41e6fbf3ee0bf499007883d80c0a79d
https://doi.org/10.1016/j.placenta.2014.08.090
https://doi.org/10.1016/j.placenta.2014.08.090
Publikováno v:
Journal of Cardiovascular Pharmacology. 57:154-165
Exposure to perinatal hypoxia results in alteration of the adult pulmonary circulation, which is linked among others to alterations in K(+) channels in pulmonary artery (PA) smooth muscle cells. In particular, large conductance Ca(2+)-activated K(+)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4daefd4128b38014c4d3da27e75fa9b
https://doi.org/10.1097/fjc.0b013e3182016adf
https://doi.org/10.1097/fjc.0b013e3182016adf
Autor:
Lucas Liaudet, Jean-François Tolsa, Stefano Di Bernardo, Mathieu Marino, Giacomo Diaceri, Anne-Christine Peyter, Vincent Muehlethaler
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 295:L201-L213
Perinatal adverse events such as limitation of nutrients or oxygen supply are associated with the occurrence of diseases in adulthood, like cardiovascular diseases and diabetes. We investigated the long-term effects of perinatal hypoxia on the lung c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7df276fe1980d8b5f8669356fb82f43
https://doi.org/10.1152/ajplung.00264.2007
https://doi.org/10.1152/ajplung.00264.2007
Publikováno v:
Science Advances, vol. 1, no. 6, pp. e1500112
Science Advances
Science Advances
Humoral immune tolerance to the therapeutic enzyme E. coli l-asparaginase was induced by engineering the enzyme for in vivo erythrocyte binding.
Antigen-specific immune responses to protein drugs can hinder efficacy and compromise safety because
Antigen-specific immune responses to protein drugs can hinder efficacy and compromise safety because
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e775341744b21d2f80f9c90cd9d02e
https://doi.org/10.1126/sciadv.1500112
https://doi.org/10.1126/sciadv.1500112
Autor:
Anne-Christine Peyter, Flavien Delhaes, Steeve Menétrey, Jean-François Tolsa, Giacomo Diaceri
Publikováno v:
BioMed Research International, Vol 2014 (2014)
Biomed Research International, pp. 949361
BioMed Research International
Biomed Research International, pp. 949361
BioMed Research International
Adverse events in utero are associated with the occurrence of chronic diseases in adulthood. We previously demonstrated in mice that perinatal hypoxia resulted in altered pulmonary circulation in adulthood, with a decreased endothelium-dependent rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28439c59f9aca22dc3008bbf7870be3
https://doaj.org/article/c8761af0d84d412a9119173d40934ed4
https://doaj.org/article/c8761af0d84d412a9119173d40934ed4
Autor:
Anne-Christine Peyter, Giacomo Diaceri, Jean-François Tolsa, Jean-Louis Bény, Rostislav Bychkov, Mathieu Marino
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 293(5)
Adverse events during the perinatal period, like hypoxia, have been associated with adult diseases. In pulmonary vessels, K+channels play an important role in the regulation of vascular tone. In the fetus, Ca2+-activated K+channels (KCa) are predomin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34525c4d4229392c88b2225820443b3
https://pubmed.ncbi.nlm.nih.gov/17720874
https://pubmed.ncbi.nlm.nih.gov/17720874
Publikováno v:
Scientific Reports
New approaches based on induction of antigen-specific immunological tolerance are being explored for treatment of autoimmunity and prevention of immunity to protein drugs. Antigens associated with apoptotic debris are known to be processed tolerogeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b45bfdb402d615fd5da4edb49d069f
https://infoscience.epfl.ch/record/214007
https://infoscience.epfl.ch/record/214007