Zobrazeno 1 - 10
of 841
pro vyhledávání: '"Giacobini, P."'
Autor:
Malene Lundgaard Riis, Gaspard Delpouve, John E. Nielsen, Cecilie Melau, Lea Langhoff Thuesen, Kristine Juul Hare, Eva Dreisler, Kasper Aaboe, Pia Tutein Brenøe, Jakob Albrethsen, Hanne Frederiksen, Anders Juul, Paolo Giacobini, Anne Jørgensen
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Sex-specific gonadal differentiation is directed by complex signalling promoting development in either male or female direction, while simultaneously inhibiting the opposite pathway. In mice, the WNT/β-catenin pathway promotes ovarian devel
Externí odkaz:
https://doaj.org/article/9ba84127f86e43e4b357207164f53583
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Multimorbidity is typically associated with deficient health-related quality of life in mid-life, and the likelihood of developing multimorbidity in women is elevated. We address the issue of data sparsity in non-prevalent feature
Externí odkaz:
https://doaj.org/article/65f2b0e4e1484573bc0ade3696fb77b8
Autor:
Isabel Paiva, Jonathan Seguin, Iris Grgurina, Akash Kumar Singh, Brigitte Cosquer, Damien Plassard, Laura Tzeplaeff, Stephanie Le Gras, Ludovica Cotellessa, Charles Decraene, Johanne Gambi, Rafael Alcala-Vida, Muthusamy Eswaramoorthy, Luc Buée, Jean-Christophe Cassel, Paolo Giacobini, David Blum, Karine Merienne, Tapas K. Kundu, Anne-Laurence Boutillier
Publikováno v:
Neurobiology of Disease, Vol 198, Iss , Pp 106538- (2024)
Aging is the main risk factor of cognitive neurodegenerative diseases such as Alzheimer's disease, with epigenome alterations as a contributing factor. Here, we compared transcriptomic/epigenomic changes in the hippocampus, modified by aging and by t
Externí odkaz:
https://doaj.org/article/f5714d9bc754442fab0e4c7aa97ead64
Autor:
Dayana Benny, Mario Giacobini, Alberto Catalano, Giuseppe Costa, Roberto Gnavi, Fulvio Ricceri
Publikováno v:
JMIR Public Health and Surveillance, Vol 10, p e52353 (2024)
BackgroundMultimorbidity is a significant public health concern, characterized by the coexistence and interaction of multiple preexisting medical conditions. This complex condition has been associated with an increased risk of COVID-19. Individuals w
Externí odkaz:
https://doaj.org/article/52ed847fd4da44178816b118b69c4040
Autor:
Julien Cicero, Sarah Trouvilliez, Martine Palma, Gaetan Ternier, Laurine Decoster, Eloise Happernegg, Nicolas Barois, Alexandre Van Outryve, Lucie Dehouck, Roland P. Bourette, Eric Adriaenssens, Chann Lagadec, Cagatay Mehmet Tarhan, Dominique Collard, Zied Souguir, Elodie Vandenhaute, Grégory Maubon, François Sipieter, Nicolas Borghi, Fumitaka Shimizu, Takashi Kanda, Paolo Giacobini, Fabien Gosselet, Nathalie Maubon, Xuefen Le Bourhis, Isabelle Van Seuningen, Caroline Mysiorek, Robert-Alain Toillon
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-20 (2023)
Abstract Background Triple-Negative Breast Cancer is particularly aggressive, and its metastasis to the brain has a significant psychological impact on patients' quality of life, in addition to reducing survival. The development of brain metastases i
Externí odkaz:
https://doaj.org/article/a669d848d8994ea18bb634e2c30e3e37
Autor:
Rodrigues, Nuno M., Batista, João E., Trujillo, Leonardo, Duarte, Bernardo, Giacobini, Mario, Vanneschi, Leonardo, Silva, Sara
We present a novel approach for time series classification where we represent time series data as plot images and feed them to a simple CNN, outperforming several state-of-the-art methods. We propose a simple and highly replicable way of plotting the
Externí odkaz:
http://arxiv.org/abs/2102.04179
Autor:
Mauro S.B. Silva, Laurine Decoster, Gaspard Delpouve, Tori Lhomme, Gaetan Ternier, Vincent Prevot, Paolo Giacobini
Publikováno v:
EBioMedicine, Vol 97, Iss , Pp 104850- (2023)
Summary: Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder leading to anovulatory infertility. Abnormalities in the central neuroendocrine system governed by gonadotropin-releasing hormone (GnRH) neurons might be rela
Externí odkaz:
https://doaj.org/article/4aa80d697909444dbab4b1bb8fa76d8f
Autor:
Florent Sauve, Sreekala Nampoothiri, Sophie A. Clarke, Daniela Fernandois, Caio Fernando Ferreira Coêlho, Julie Dewisme, Edouard G. Mills, Gaetan Ternier, Ludovica Cotellessa, Cristina Iglesias-Garcia, Helge Mueller-Fielitz, Thibaud Lebouvier, Romain Perbet, Vincent Florent, Marc Baroncini, Ariane Sharif, June Ereño-Orbea, Maria Mercado-Gómez, Asis Palazon, Virginie Mattot, Florence Pasquier, Sophie Catteau-Jonard, Maria Martinez-Chantar, Erik Hrabovszky, Mercé Jourdain, Dominique Deplanque, Annamaria Morelli, Giulia Guarnieri, Laurent Storme, Cyril Robil, François Trottein, Ruben Nogueiras, Markus Schwaninger, Pascal Pigny, Julien Poissy, Konstantina Chachlaki, Claude-Alain Maurage, Paolo Giacobini, Waljit Dhillo, S. Rasika, Vincent Prevot
Publikováno v:
EBioMedicine, Vol 96, Iss , Pp 104784- (2023)
Summary: Background: We have recently demonstrated a causal link between loss of gonadotropin-releasing hormone (GnRH), the master molecule regulating reproduction, and cognitive deficits during pathological aging, including Down syndrome and Alzheim
Externí odkaz:
https://doaj.org/article/805ae189cc654b398588ba98e00a06f8
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Akademický článek
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