Výsledky vyhledávání - "Gia-Gia T Hò"

Akademický článek

Soluble HLA-G and HLA-G Bearing Extracellular Vesicles Affect ILT-2 Positive and ILT-2 Negative CD8 T Cells Complementary

Autor: Esther Schwich, Gia-Gia T. Hò, Joel LeMaoult, Christina Bade-Döding, Edgardo D. Carosella, Peter A. Horn, Vera Rebmann

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Tumor immune escape is associated with both, the expression of immune checkpoint molecules on peripheral immune cells and soluble forms of the human leukocyte antigen-G (HLA-G) in the blood, which are consequently discussed as clinical biomarker for

Externí odkaz: https://doaj.org/article/48d6ee5d11204399905077b4b10f26d8

Zobrazit plný text záznamu

Akademický článek

Carbamazepine-Mediated Adverse Drug Reactions: CBZ-10,11-epoxide but Not Carbamazepine Induces the Alteration of Peptides Presented by HLA-B∗15:02

Autor: Gwendolin S. Simper, Gia-Gia T. Hò, Alexander A. Celik, Trevor Huyton, Joachim Kuhn, Heike Kunze-Schumacher, Rainer Blasczyk, Christina Bade-Döding

Publikováno v: Journal of Immunology Research, Vol 2018 (2018)

Among patients treated with the anticonvulsive and psychotropic drug carbamazepine (CBZ), approximately 10% develop severe and life-threatening adverse drug reactions. These immunological conditions are resolved upon withdrawal of the medicament, sug

Externí odkaz: https://doaj.org/article/eb48a40aa6774e85aad83177fc2a6861

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

The Mechanistic Differences in HLA-Associated Carbamazepine Hypersensitivity

Autor: Gwendolin S. Simper, Lareen S. Gräser, Alexander A. Celik, Joachim Kuhn, Heike Kunze-Schumacher, Gia-Gia T. Hò, Rainer Blasczyk, Andreas Pich, Christina Bade-Doeding

Publikováno v: Pharmaceutics, Vol 11, Iss 10, p 536 (2019)

Drug hypersensitivity reactions that resemble acute immune reactions are linked to certain human leucocyte antigen (HLA) alleles. Severe and life-threatening Stevens Johnson Syndrome and Toxic Epidermal Necrolysis following treatment with the antiepi

Externí odkaz: https://doaj.org/article/b99fafc7a8614be7a7444321e4fb5c07

Zobrazit plný text záznamu

Plný text ve formátu HTML

HLA-F*01:01 presents peptides with N-terminal flexibility and a preferred length of 16 residues

Autor: Funmilola J. Heinen, Christina Bade-Döding, Rainer Blasczyk, Gia-Gia T Hò, Trevor Huyton

Publikováno v: Immunogenetics

HLA-F belongs to the non-classical HLA-Ib molecules with a marginal polymorphic nature and tissue-restricted distribution. HLA-F is a ligand of the NK cell receptor KIR3DS1, whose activation initiates an antiviral downstream immune response and lead

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2bc8de2671b6d5addc5a404233f6a4c
https://doi.org/10.1007/s00251-019-01112-1

Zobrazit plný text záznamu

The Loss of HLA-F/KIR3DS1 Ligation Is Mediated by Hemoglobin Peptides

Autor: Wiebke Hiemisch, Georg M. N. Behrens, Andreas Pich, Christina Bade-Doeding, Gia-Gia T Hò, Rainer Blasczyk

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 8012, p 8012 (2020)

The human leukocyte antigen (HLA)-Ib molecule, HLA-F, is known as a CD4+ T-cell protein and mediator of HIV progression. While HLA-Ia molecules do not have the chance to select and present viral peptides for immune recognition due to protein downregu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496d2719d3dfdda7728c8e08fe98d575

Zobrazit plný text záznamu

Plný text ve formátu HTML

HLA-F Allele-Specific Peptide Restriction Represents an Exceptional Proteomic Footprint

Autor: Funmilola J. Heinen, Christina Bade-Doeding, Rainer Blasczyk, Gia-Gia T Hò, Andreas Pich

Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 22, p 5572 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 22

Peptide-dependent engagement between human leucocyte antigens class I (HLA-I) molecules and their cognate receptors has been extensively analyzed. HLA-F belongs to the non-classical HLA-Ib molecules with marginal polymorphic nature and tissue restric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b51037f86bfad396eb6e53b35242e3ff
https://www.mdpi.com/1422-0067/20/22/5572

Zobrazit plný text záznamu

Plný text ve formátu HTML

Releasing the concept of HLA-allele specific peptide anchors in viral infections: A non-canonical naturally presented human cytomegalovirus-derived HLA-A*24:02 restricted peptide drives exquisite immunogenicity

Autor: Wiebke C Pump, Rainer Blasczyk, Jörg Martens, Trevor Huyton, Christina Bade-Doeding, Gia-Gia T Hò, Heike Kunze-Schumacher, Rebecca Schulz

Publikováno v: HLA: Immune Response Genetics
Hla

T-cell receptors possess the unique ability to survey and respond to their permanently modified ligands, self HLA-I molecules bound to non-self peptides of various origin. This highly specific immune function is impaired following hematopoietic stem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e4d86a87fa21c80cdca9607ff0bc24
https://hdl.handle.net/21.11116/0000-0003-DDCA-121.11116/0000-0003-DDCB-021.11116/0000-0003-DDC7-421.11116/0000-0003-DDC9-221.11116/0000-0003-DDCC-F

Zobrazit plný text záznamu

Between Innate and Adaptive Immune Responses: NKG2A, NKG2C, and CD8+ T Cell Recognition of HLA-E Restricted Self-Peptides Acquired in the Absence of HLA-Ia

Autor: Trevor Huyton, Rainer Blasczyk, Thomas Kraemer, Wiebke C Pump, Christina Bade-Doeding, Gia-Gia T Hò

Publikováno v: International Journal of Molecular Sciences
Volume 20
Issue 6
International Journal of Molecular Sciences, Vol 20, Iss 6, p 1454 (2019)

On healthy cells the non-classical HLA class Ib molecule HLA-E displays the cognate ligand for the NK cell receptor NKG2A/CD94 when bound to HLA class I signal peptide sequences. In a pathogenic situation when HLA class I is absent, HLA-E is bound to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43281d83b626ab4da32d6e08459d4135

Zobrazit plný text záznamu

Plný text ve formátu HTML

NKG2A/CD94 Is a New Immune Receptor for HLA-G and Distinguishes Amino Acid Differences in the HLA-G Heavy Chain

Autor: Alexander A. Celik, Rainer Blasczyk, Wiebke Hiemisch, Christina Bade-Doeding, Gwendolin S. Simper, Gia-Gia T Hò, Trevor Huyton

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 4362, p 4362 (2020)
Volume 21
Issue 12

Natural killer (NK) cell therapies are a tool to antagonize a dysfunctional immune system. NK cells recognize malignant cells, traffic to a tumor location, and infiltrate the solid tumor. The immune checkpoint molecule human leukocyte antigen (HLA)-G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdcaae030e4db804a12aa6b8a140e6b9
https://doi.org/10.3390/ijms21124362

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání