Zobrazeno 1 - 10
of 30
pro vyhledávání: '"GiWon Shin"'
Autor:
Ho Jung An, Mira A. Partha, HoJoon Lee, Billy T. Lau, Dmitri S. Pavlichin, Alison Almeda, Anna C. Hooker, Giwon Shin, Hanlee P. Ji
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
BackgroundColon microbiome composition contributes to the pathogenesis of colorectal cancer (CRC) and prognosis. We analyzed 16S rRNA sequencing data from tumor samples of patients with metastatic CRC and determined the clinical implications.Material
Externí odkaz:
https://doaj.org/article/f36916f7469247408cf94f0de232d4f5
Autor:
GiWon Shin, Stephanie U. Greer, Erik Hopmans, Susan M. Grimes, HoJoon Lee, Lan Zhao, Laura Miotke, Carlos Suarez, Alison F. Almeda, Sigurdis Haraldsdottir, Hanlee P. Ji
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021)
Abstract We developed a sensitive sequencing approach that simultaneously profiles microsatellite instability, chromosomal instability, and subclonal structure in cancer. We assessed diverse repeat motifs across 225 microsatellites on colorectal carc
Externí odkaz:
https://doaj.org/article/f712076aec7c479ebafdae1d3b8bdf16
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Small RNAs that originate from transfer RNA (tRNA) species, tRNA-derived fragments (tRFs), play diverse biological functions but little is known for their association with aging. Moreover, biochemical aspects of tRNAs limit discovery of func
Externí odkaz:
https://doaj.org/article/671708ab310442aba73295f37f88d034
Autor:
Billy T. Lau, Dmitri Pavlichin, Anna C. Hooker, Alison Almeda, Giwon Shin, Jiamin Chen, Malaya K. Sahoo, Chun Hong Huang, Benjamin A. Pinsky, Ho Joon Lee, Hanlee P. Ji
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-23 (2021)
Abstract Background The genome of SARS-CoV-2 is susceptible to mutations during viral replication due to the errors generated by RNA-dependent RNA polymerases. These mutations enable the SARS-CoV-2 to evolve into new strains. Viral quasispecies emerg
Externí odkaz:
https://doaj.org/article/6c281c23b3f34308a56ed35fdc580c16
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Microsatellite genotyping is a common molecular method of for identification but current methods have restricted throughput. The authors demonstrate STR-Seq, which combines next generation sequencing with targetedin vitroCRISPR-Cas9 fragmentation to
Externí odkaz:
https://doaj.org/article/1fd514e535d042ffa2a18a3e8a9b6a4c
Autor:
Bo Zhou, Purmann, Carolin, Hanmin Guo, GiWon Shin, Yiling Huang, Pattni, Reenal, Qingxi Meng, Greer, Stephanie U., Roychowdhury, Tanmoy, Wood, Raegan N., Ho, Marcus, zu Dohna, Heinrich, Abyzov, Alexej, Hallmayer, Joachim F., Wong, Wing H., Ji, Hanlee P., Urban, Alexander E.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 7/30/2024, Vol. 121 Issue 31, p1-12, 20p
Autor:
Alison F. Almeda, Susan M. Grimes, HoJoon Lee, Stephanie Greer, GiWon Shin, Madeline McNamara, Anna C. Hooker, Maya M. Arce, Matthew Kubit, Marie C. Schauer, Paul Van Hummelen, Cindy Ma, Meredith A. Mills, Robert J. Huang, Joo Ha Hwang, Manuel R. Amieva, Summer S. Han, James M. Ford, Hanlee P. Ji
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 31:1693-1700
Background: Gastric cancer is a leading cause of cancer morbidity and mortality. Developing information systems which integrate clinical and genomic data may accelerate discoveries to improve cancer prevention, detection, and treatment. To support tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2420a3df45c56f266d55015be6caf5
https://doi.org/10.1158/1055-9965.epi-22-0308
https://doi.org/10.1158/1055-9965.epi-22-0308
Autor:
Ingrid P. Vogelaar, Stephanie Greer, Fan Wang, GiWon Shin, Billy Lau, Yajing Hu, Sigurdis Haraldsdottir, Rocio Alvarez, Dennis Hazelett, Peter Nguyen, Francesca P. Aguirre, Maha Guindi, Andrew Hendifar, Jessica Balcom, Anna Leininger, Beth Fairbank, Hanlee Ji, Megan P. Hitchins
Publikováno v:
Cancers; Volume 15; Issue 1; Pages: 228
Cancers, vol 15, iss 1
Cancers, vol 15, iss 1
Lynch syndrome (LS), caused by heterozygous pathogenic variants affecting one of the mismatch repair (MMR) genes (MSH2, MLH1, MSH6, PMS2), confers moderate to high risks for colorectal, endometrial, and other cancers. We describe a four-generation, 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061eaf60f38d8f1ffee10414ce8f65ed
Autor:
Hanlee P. Ji, Lan Zhao, Susan M. Grimes, Stephanie U. Greer, Carlos Suárez, Erik S. Hopmans, Alison Almeda, GiWon Shin, Hojoon Lee, Laura Miotke, Sigurdis Haraldsdottir
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021)
Genome Medicine
Genome Medicine
Colorectal carcinomas (CRCs) which have lost DNA mismatch repair display hypermutability evident in a molecular phenotype called microsatellite instability (MSI). These mismatch repair deficient tumors are thought to lack widespread genomic instabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b68d90ab0c2a44b6b7ab53ee66ed201
https://doaj.org/article/f712076aec7c479ebafdae1d3b8bdf16
https://doaj.org/article/f712076aec7c479ebafdae1d3b8bdf16
Autor:
Bo Zhou, GiWon Shin, Lisanne Vervoort, Stephanie Greer, Yiling Huang, Tanmoy Roychowdhury, Reenal Pattni, Alexej Abyzov, Joris Vermeesch, Hanlee Ji, Alexander Urban
Publikováno v:
European Neuropsychopharmacology. 63:e88-e89
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b7ca51430707904ed040bc3d2a9e6f2
https://doi.org/10.1016/j.euroneuro.2022.07.166
https://doi.org/10.1016/j.euroneuro.2022.07.166