Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gi Soo Kang"'
Autor:
Gi Soo Kang, Eric M. Billings, Xiaoyan Shen, Joel Moss, Kelsey Grolig, Xiong Cai, Thomas N. Darling, Gustavo Pacheco-Rodriguez, Qingyuan Fan
Publikováno v:
J Invest Dermatol
Tuberous sclerosis complex (TSC) is an autosomal-dominant disorder characterized by hamartomatous tumors of the skin, kidneys, brain, and lungs. TSC is caused by mutations in the TSC1 and TSC2 genes, which result in hyperactivation of the mTOR, leadi
Autor:
Gi Soo Kang1, Gillespie, Patricia Anne1, Gunnison, Albert1, Moreira, Andre Luis2, Kam-Meng Tchou-Wong1, Lung-Chi Chen1
Publikováno v:
Environmental Health Perspectives. Feb2011, Vol. 119 Issue 2, p176-181. 6p. 1 Color Photograph, 4 Graphs.
Autor:
Lung Chi Chen, Albert F. Gunnison, Patricia A. Gillespie, Kam-Meng Tchou-Wong, Gi Soo Kang, Andre L. Moreira
Publikováno v:
Environmental Health Perspectives
Background Because associations have been reported between inhaled ambient ultrafine particles and increased risk of cardiopulmonary disease, it has been suggested that inhaled engineered nanoparticles (NPs) may also induce adverse effects on the car
Autor:
Kam-Meng Tchou-Wong, Alison Elder, Terry Gordon, Robert Gelein, Lung Chi Chen, Andre L. Moreira, Patricia A. Gillespie, Gi Soo Kang, Lu Chen, Jeffrey T. Koberstein
Publikováno v:
Nanotoxicology. 4:106-119
Short and long-term pulmonary response to inhaled nickel hydroxide nanoparticles (nano-Ni(OH)(2), CMD = 40 nm) in C57BL/6 mice was assessed using a whole body exposure system. For short-term studies mice were exposed for 4 h to nominal concentrations
Autor:
Krystal Cates, Joel Moss, Gustavo Pacheco-Rodriguez, Gi Soo Kang, Patricia S. Connelly, Martha Vaughan, Mathew P. Daniels, Víctor Meza-Carmen
Publikováno v:
The FASEB Journal. 26
Autor:
Souheil El-Chemaly, Martha Vaughan, Gi Soo Kang, Jiro Kato, Chun-Yi Zhang, Joel Moss, Alessandro Vichi, D. Michael Payne, Gustavo Pacheco-Rodriguez, Chiara Donati, Víctor Meza-Carmen, Mario Stylianou
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(26)
ADP-ribosylation factor domain protein 1 (ARD1) is a 64-kDa protein containing a functional ADP-ribosylation factor (GTP hydrolase, GTPase), GTPase-activating protein, and E3 ubiquitin ligase domains. ARD1 activation by the guanine nucleotide-exchang
Publikováno v:
Toxicological Research
It has been proposed that acute phase response can be a mechanism by which inhaled particles exert adverse effects on the cardiovascular system. Although some of the human acute phase proteins have been widely studied as biomarkers of systemic inflam
Autor:
Hernán R. Rengifo, Gi Soo Kang, Jeffrey T. Koberstein, Patricia A. Gillespie, Lung Chi Chen, Albert F. Gunnison
Publikováno v:
Inhalation toxicology. 23(2)
In this pilot study, we investigated which physicochemical properties of nickel hydroxide nanoparticles (nano-NH) were mainly responsible in inducing pulmonary toxicity. First, we studied the role of nickel ions solubilized from nano-NH by comparing
Publikováno v:
Mutation research. 610(1-2)
Several metals are carcinogenic but little is known about the mechanisms by which they cause cancer. A pathway that may contribute to metal ion induced carcinogenesis is by hypoxia signaling, which involves a disruption of cellular iron homeostasis b
Publikováno v:
Chemosphere. 67(11)
This study evaluated the effects of an industrial wastewater treatment plant (IWTP) and a municipal wastewater treatment plant (MWTP) effluents on a variety of bioindicators ranging from biochemical, organism, and population-level responses in pale c