Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gi Hun, Bae"'
Autor:
Heejin Lee, Hye‐Ji Kim, Dong‐Kyu Choi, Eu n.‐A. Ko, Jae‐Hyeog Choi, Yohan Seo, Sion Lee, Soong‐Hyun Kim, Sejin Jung, Minwoo Kim, Dongwan Kang, Chun‐Young Im, Gi‐Hun Bae, Sung‐Cherl Jung, Oh‐Bin Kwon
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 5, Pp n/a-n/a (2023)
Abstract The importance of vesicular monoamine transporter 2 (VMAT2) in dopamine regulation, which is considered crucial for neuropsychiatric disorders, is currently being studied. Moreover, the development of disease treatments using histone deacety
Externí odkaz:
https://doaj.org/article/a831498fedc040b8a74e3e58dc2baca1
Autor:
Hye Yun Kim, Da Won Kim, Seungpyo Hong, Sunhee Lee, Jisu Shin, Kyeonghwan Kim, Hanna Jeon, Young-Soo Kim, Gi Hun Bae, Ikyon Kim
Publikováno v:
ACS Chemical Neuroscience. 12:99-108
Amyloid-β (Aβ) aggregated forms are highly associated with the onset of Alzheimer's disease (AD). Aβ abnormally accumulates in the brain and induces neuronal damages and symptoms of AD such as cognitive impairment and memory loss. Since an antibod
Publikováno v:
RSC Advances. 10:7265-7288
A modular approach to polycyclic N-fused heteroaromatics is described. Acid-catalyzed reactions of various 1-(2-oxo-2-arylethyl)-1H-pyrrole-2-carbaldehydes with several o-phenylenediamines provided facile access to a number of new benzo[d]imidazole-p
Publikováno v:
The Journal of Organic Chemistry. 84:6916-6927
Efficient construction of new chemical space by way of strategic use of tandem reactions is highly important in drug discovery. Described herein is an atom-economical [4+1+1] annulation approach to 3-(hetero)aryl-4-acyl-3,4-dihydropyrrolo[1,2- a]pyra
Autor:
Mi-Kyung Park, Hyeon Min Cha, Jinhwang Kim, Dileep Kumar Singh, Seong Hee Kim, Gi Hun Bae, Ikyon Kim
Publikováno v:
Journal of Heterocyclic Chemistry.
Autor:
Gi Hun, Bae, Suzi, Kim, Na Keum, Lee, Anuradha, Dagar, Jeong Hwa, Lee, Jeeyeon, Lee, Ikyon, Kim
Publikováno v:
RSC advances. 10(12)
A modular approach to polycyclic N-fused heteroaromatics is described. Acid-catalyzed reactions of various 1-(2-oxo-2-arylethyl)-1
Autor:
Seungyeop Baek, Hanna Jeon, Gi Hun Bae, Sejin Lee, Youngeun Jung, Ikyon Kim, Jung Min Han, Naewoo Neo Shin, Keunwan Park, Hee Chan Yoo, Young-Soo Kim, Seung-Hoon Yang
Publikováno v:
ACS chemical neuroscience. 10(6)
Recent clinical approvals of brain imaging radiotracers targeting amyloid-β provided clinicians the tools to detect and confirm Alzheimer's disease pathology without autopsy or biopsy. While current imaging agents are effective in postsymptomatic Al