Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Gi Hoon Son"'
Autor:
Inah Park, Mijung Choi, Jeongah Kim, Sangwon Jang, Doyeon Kim, Jihoon Kim, Youngshik Choe, Dongho Geum, Seong-Woon Yu, Ji-Woong Choi, Cheil Moon, Han Kyoung Choe, Gi Hoon Son, Kyungjin Kim
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Affective disorders are frequently associated with disrupted circadian rhythms. The existence of rhythmic secretion of central serotonin (5-hydroxytryptamine, 5-HT) pattern has been reported; however, the functional mechanism underlying the
Externí odkaz:
https://doaj.org/article/b2108cc02c6b4bdcb227ea2ddd2b981e
Publikováno v:
Data in Brief, Vol 52, Iss , Pp 109948- (2024)
Adrenal corticosteroid biosynthesis dysregulation can give rise to various pathological conditions, such as Cushing's syndrome, a disorder characterized by the sustained and excessive production of cortisol. Despite the development of several classes
Externí odkaz:
https://doaj.org/article/b0f0e2a80b5e4249806d57780f141336
Autor:
Jae Woo Park, Eun Roh, Gil Myoung Kang, So Young Gil, Hyun Kyong Kim, Chan Hee Lee, Won Hee Jang, Se Eun Park, Sang Yun Moon, Seong Jun Kim, So Yeon Jeong, Chae Beom Park, Hyo Sun Lim, Yu Rim Oh, Han Na Jung, Obin Kwon, Byung Soo Youn, Gi Hoon Son, Se Hee Min, Min-Seon Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Nicotinamide phosphoribosyl transferase (NAMPT) is a critical regulator of cellular nicotinamide adenine dinucleotide (NAD)+ levels. Here, the authors show that blood NAMPT contributes to the circadian rhythm generation of locomotor activity and ener
Externí odkaz:
https://doaj.org/article/1ae6309a19ce496a8d96ad2bf3643e37
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 770 (2024)
REV-ERBα and its paralog, REV-ERBβ, encoded by NR1D1 and NR1D2 genes, are key nuclear receptors that link the circadian timing system and metabolic homeostasis. Since heme is an endogenous ligand, REV-ERBs have been considered key components of the
Externí odkaz:
https://doaj.org/article/5f079e4b700144a59032c6463b5154bb
Autor:
Hyun Jung Kim, Hyeijung Yoo, Ji Yeon Kim, Soo Hyun Yang, Hyun Woo Lee, Heon-Jeong Lee, Gi Hoon Son, Hyun Kim
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-5 (2022)
Abstract The habenula (Hb) is an epithalamic structure that links multiple forebrain areas with the mid/hindbrain monoaminergic systems. As an anti-reward center, it has been implicated in the etiology of various neuropsychiatric disorders, particula
Externí odkaz:
https://doaj.org/article/950e281123c14e3c9730ae159254c39f
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 3, Pp 473-484 (2020)
Circadian rhythms: Maternal stress can disrupt adult offspring’s biological clock When pregnant mothers are stressed, the fetus’s circadian rhythms are reprogrammed, increasing the risk of health complications later in life. Stress during pregnan
Externí odkaz:
https://doaj.org/article/f744ad0b8c104b849311da5a1810008a
Autor:
Yong Uk Jeong, Hyo-Eon Jin, Hye Young Lim, Goyeong Choi, Hansol Joo, Bohun Kang, Ga-Hyun Lee, Kwang-Hyeon Liu, Han-Joo Maeng, Sooyoung Chung, Gi Hoon Son, Jong-Wha Jung
Publikováno v:
Pharmaceuticals, Vol 14, Iss 6, p 496 (2021)
Circadian dysfunction is closely associated with an increased risk of various diseases. Considering that molecular clock machinery serves as an intrinsic time-keeping system underlying the circadian rhythm of biological processes, the modulation of t
Externí odkaz:
https://doaj.org/article/d0999fc6d66d477fbf6faf33d1e28859
Autor:
Seongsik Yun, Arfaxad Reyes-Alcaraz, Yoo-Na Lee, Hyo Jeong Yong, Jeewon Choi, Byung-Joo Ham, Jong-Woo Sohn, Dong-Hoon Kim, Gi Hoon Son, Hyun Kim, Soon-Gu Kwon, Dong Sik Kim, Bong Chul Kim, Jong-Ik Hwang, Jae Young Seong
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Despite the established comorbidity between mood disorders and abnormal eating behaviors, the underlying molecular mechanism and therapeutics remain to be resolved. Here, we show that a spexin-based galanin receptor type 2 agonist (SG2A) simultaneous
Externí odkaz:
https://doaj.org/article/3bd03b366ad241c68e3ed73f1eea03d4
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2019)
Circadian rhythms regulate many biological processes and play fundamental roles in behavior, physiology, and metabolism. Such periodicity is critical for homeostasis because disruption or misalignment of the intrinsic rhythms is associated with the o
Externí odkaz:
https://doaj.org/article/d5c1c3e3b0c74a8fb3b7cc01aa2faf06
Autor:
Thomas M. Sanderson, Clarrisa A. Bradley, John Georgiou, Yun Hwa Hong, Ai Na Ng, Yeseul Lee, Hee-Dae Kim, Doyeon Kim, Mascia Amici, Gi Hoon Son, Min Zhuo, Kyungjin Kim, Bong-Kiun Kaang, Sang Jeong Kim, Graham L. Collingridge
Publikováno v:
Cell Reports, Vol 25, Iss 13, Pp 3631-3646.e3 (2018)
Summary: A major mechanism contributing to synaptic plasticity involves alterations in the number of AMPA receptors (AMPARs) expressed at synapses. Hippocampal CA1 synapses, where this process has been most extensively studied, are highly heterogeneo
Externí odkaz:
https://doaj.org/article/d290921b5af4434592a52c654baf45fc