Cell cycle gene expression networks discovered using systems biology: Significance in carcinogenesis

Autor: Scott, RE, Ghule, PN, Stein, JL, Stein, GS

The early stages of carcinogenesis are linked to defects in the cell cycle. A series of cell cycle checkpoints are involved in this process. The G1/S checkpoint that serves to integrate the control of cell proliferation and differentiation is linked

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f8ad914a255f7be013e39cd856912487
https://europepmc.org/articles/PMC4481160/

Bromodomain Proteins Epigenetically Regulate the Mitotically Associated lncRNA MANCR in Triple Negative Breast Cancer Cells.

Autor: Tracy KM; Department of Biochemistry, University of Vermont Larner College of Medicine, Burlington, VT 05405., Prior S; Department of Biomedical and Health Sciences, University of Vermont College of Nursing and Health Sciences, Burlington, VT 05405., Trowbridge WT; Department of Biochemistry, University of Vermont Larner College of Medicine, Burlington, VT 05405., Boyd JR; Department of Biomedical and Health Sciences, University of Vermont College of Nursing and Health Sciences, Burlington, VT 05405., Ghule PN; Department of Biochemistry, University of Vermont Larner College of Medicine, Burlington, VT 05405; Department of Biomedical and Health Sciences, University of Vermont College of Nursing and Health Sciences, Burlington, VT 05405., Frietze S; Department of Biochemistry, University of Vermont Larner College of Medicine, Burlington, VT 05405; Department of Biomedical and Health Sciences, University of Vermont College of Nursing and Health Sciences, Burlington, VT 05405; University of Vermont Cancer Center, University of Vermont Larner College of Medicine, Burlington, VT 05405., Stein JL; Department of Biochemistry, University of Vermont Larner College of Medicine, Burlington, VT 05405; University of Vermont Cancer Center, University of Vermont Larner College of Medicine, Burlington, VT 05405., Stein GS; Department of Biochemistry, University of Vermont Larner College of Medicine, Burlington, VT 05405; University of Vermont Cancer Center, University of Vermont Larner College of Medicine, Burlington, VT 05405., Lian JB; Department of Biochemistry, University of Vermont Larner College of Medicine, Burlington, VT 05405; University of Vermont Cancer Center, University of Vermont Larner College of Medicine, Burlington, VT 05405.

Publikováno v: Critical reviews in eukaryotic gene expression [Crit Rev Eukaryot Gene Expr] 2024; Vol. 34 (2), pp. 61-71.

LINC01638 sustains human mesenchymal stem cell self-renewal and competency for osteogenic cell fate.

Autor: Gordon JAR; Department of Biochemistry, University of Vermont, Burlington, VT, 05405, USA.; University of Vermont Cancer Center, Larner College of Medicine, University of Vermont, 89 Beaumont Avenue, Burlington, VT, 05405, USA., Tye CE; Department of Biochemistry, University of Vermont, Burlington, VT, 05405, USA.; University of Vermont Cancer Center, Larner College of Medicine, University of Vermont, 89 Beaumont Avenue, Burlington, VT, 05405, USA., Banerjee B; Department of Biochemistry, University of Vermont, Burlington, VT, 05405, USA., Ghule PN; Department of Biochemistry, University of Vermont, Burlington, VT, 05405, USA.; University of Vermont Cancer Center, Larner College of Medicine, University of Vermont, 89 Beaumont Avenue, Burlington, VT, 05405, USA., van Wijnen AJ; Department of Biochemistry, University of Vermont, Burlington, VT, 05405, USA., Kabala FS; Department of Biochemistry, University of Vermont, Burlington, VT, 05405, USA., Page NA; Department of Biochemistry, University of Vermont, Burlington, VT, 05405, USA., Falcone MM; Department of Biochemistry, University of Vermont, Burlington, VT, 05405, USA., Stein JL; Department of Biochemistry, University of Vermont, Burlington, VT, 05405, USA.; University of Vermont Cancer Center, Larner College of Medicine, University of Vermont, 89 Beaumont Avenue, Burlington, VT, 05405, USA., Stein GS; Department of Biochemistry, University of Vermont, Burlington, VT, 05405, USA.; University of Vermont Cancer Center, Larner College of Medicine, University of Vermont, 89 Beaumont Avenue, Burlington, VT, 05405, USA., Lian JB; Department of Biochemistry, University of Vermont, Burlington, VT, 05405, USA. jane.lian@uvm.edu.; University of Vermont Cancer Center, Larner College of Medicine, University of Vermont, 89 Beaumont Avenue, Burlington, VT, 05405, USA. jane.lian@uvm.edu.

Publikováno v: Scientific reports [Sci Rep] 2023 Nov 20; Vol. 13 (1), pp. 20314. Date of Electronic Publication: 2023 Nov 20.

Corrigendum to "Spatiotemporal higher-order chromatin landscape of human histone gene clusters at histone locus bodies during the cell cycle in breast cancer progression" [Gene 872 (2023) 147441].

Autor: Ghule PN; Department of Biochemistry and University of Vermont Cancer Center, Larner College of Medicine at the University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA. Electronic address: prachi.ghule@med.uvm.edu., Boyd JR; Department of Biomedical and Health Sciences and University of Vermont Cancer Center, College of Nursing and Health Sciences, University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA. Electronic address: joseph.boyd@med.uvm.edu., Kabala F; Department of Biochemistry and University of Vermont Cancer Center, Larner College of Medicine at the University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA., Fritz AJ; Department of Biochemistry and University of Vermont Cancer Center, Larner College of Medicine at the University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA. Electronic address: andrew.fritz@med.uvm.edu., Bouffard NA; Microscopy Imaging Center, Center for Biomedical Shared Resources at the University of Vermont, 150 Firestone Building, 149 Beaumont Ave, Burlington, VT 05405, USA., Gao C; Department of Biomedical and Health Sciences and University of Vermont Cancer Center, College of Nursing and Health Sciences, University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA., Bright K; Department of Biomedical and Health Sciences and University of Vermont Cancer Center, College of Nursing and Health Sciences, University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA., Macfarlane J; Department of Biochemistry and University of Vermont Cancer Center, Larner College of Medicine at the University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA., Seward DJ; Department of Pathology and University of Vermont Cancer Center, Larner College of Medicine at the University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA. Electronic address: david.seward@uvmhealth.org., Pegoraro G; High-Throughput Imaging Facility (HiTIF), Center for Cancer Research (CCR), National Cancer Institute, NIH, Bethesda, MD 20892, USA., Misteli T; Cell Biology of Genomes, Center for Cancer Research (CCR), National Cancer Institute, NIH, Bethesda, MD 20892, USA., Lian JB; Department of Biochemistry and University of Vermont Cancer Center, Larner College of Medicine at the University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA. Electronic address: jane.lian@med.uvm.edu., Frietze S; Department of Biomedical and Health Sciences and University of Vermont Cancer Center, College of Nursing and Health Sciences, University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA. Electronic address: seth.frietze@med.uvm.edu., Stein JL; Department of Biochemistry and University of Vermont Cancer Center, Larner College of Medicine at the University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA. Electronic address: janet.stein@med.uvm.edu., van Wijnen AJ; Department of Biochemistry and University of Vermont Cancer Center, Larner College of Medicine at the University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA. Electronic address: andre.vanwijnen@uvm.edu., Stein GS; Department of Biochemistry and University of Vermont Cancer Center, Larner College of Medicine at the University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA. Electronic address: gary.stein@uvm.edu.

Publikováno v: Gene [Gene] 2023 Jul 15; Vol. 873, pp. 147469. Date of Electronic Publication: 2023 May 11.

Identification of molecularly unique tumor-associated mesenchymal stromal cells in breast cancer patients.

Autor: Gordon JAR; Department of Biochemistry, Larner College of Medicine at the University of Vermont, Burlington, VT, United States of America., Evans MF; Department of Pathology and Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, United States of America., Ghule PN; Department of Biochemistry, Larner College of Medicine at the University of Vermont, Burlington, VT, United States of America., Lee K; Department of Biochemistry, Larner College of Medicine at the University of Vermont, Burlington, VT, United States of America., Vacek P; Department of Surgery, Larner College of Medicine at the University of Vermont, Burlington, VT, United States of America., Sprague BL; Department of Surgery, Larner College of Medicine at the University of Vermont, Burlington, VT, United States of America., Weaver DL; Department of Pathology and Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, United States of America., Stein GS; Department of Biochemistry, Larner College of Medicine at the University of Vermont, Burlington, VT, United States of America., Stein JL; Department of Biochemistry, Larner College of Medicine at the University of Vermont, Burlington, VT, United States of America.

Publikováno v: PloS one [PLoS One] 2023 Mar 20; Vol. 18 (3), pp. e0282473. Date of Electronic Publication: 2023 Mar 20 (Print Publication: 2023).