Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil

Autor: Sellers, Katherine J., Elliott, Christina, Jackson, Joshua, Ghosh, Anshua, Ribe, Elena, Rojo, Ana I., Jarosz-Griffiths, Heledd H., Watson, Iain A., Xia, Weiming, Semenov, Mikhail, Morin, Peter, Hooper, Nigel M., Porter, Rod, Preston, Jane, Al-Shawi, Raya, Baillie, George, Lovestone, Simon, Cuadrado, Antonio, Harte, Michael, Simons, Paul, Srivastava, Deepak P., Killick, Richard

Publikováno v: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association March 2018 14(3):306-317

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Amyloid beta synaptotoxicity is Wnt–planar cell polarity dependent and blocked by fasudil

Autor: Sellers, Katherine J., Elliott, Christina, Jackson, Joshua, Ghosh, Anshua, Ribe, Elena, Rojo-Sanchís, Ana, Jarosz-Griffiths, Heledd H., Watson, Iain A., Xia, Weiming, Semenov, Mikhail, Morin, Peter, Hooper, Nigel M., Porter, Rod, Preston, Jane, Al-Shawi, Raya, Baillie, George, Lovestone, Simon, Cuadrado, Antonio, Harte, Michael, Simons, Paul, Srivastava, Deepak P., Killick, Richard

Publikováno v: Sellers, K J, Elliott, C, Jackson, J, Ghosh, A, Ribe, E, Rojo-Sanchís, A, Jarosz-Griffiths, H H, Watson, I A, Xia, W, Semenov, M, Morin, P, Hooper, N M, Porter, R, Preston, J, Al-Shawi, R, Baillie, G, Lovestone, S, Cuadrado, A, Harte, M, Simons, P, Srivastava, D P & Killick, R 2017, ' Amyloid beta synaptotoxicity is Wnt–planar cell polarity dependent and blocked by fasudil ', Alzheimer's & Dementia . https://doi.org/10.1016/j.jalz.2017.09.008

Introduction Synapse loss is the basis of the cognitive decline indicative of dementia. In the brains of Alzheimer's disease (AD) sufferer's amyloid beta (Aβ) peptides aggregate to form senile plaques but as soluble peptides that are toxic to synaps

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2761::52ac641afcff605ea153b6834567513c
https://kclpure.kcl.ac.uk/en/publications/7ab86dcb-0658-4c91-a942-949505775d77

Female sex mitigates motor and behavioural phenotypes in TDP-43^Q331K knock-in mice.

Autor: Watkins, Jodie¹, Ghosh, Anshua², Keerie, Amy F. A.¹, Alix, James J. P.¹, Mead, Richard J.¹ r.j.mead@sheffield.ac.uk, Sreedharan, Jemeen² jemeen.sreedharan@kcl.ac.uk

Publikováno v: Scientific Reports. 11/5/2020, Vol. 10 Issue 1, pN.PAG-N.PAG. 1p.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.