High molecular mass kininogen inhibits cathepsin G-induced platelet activation by forming a complex with cathepsin G

Autor: Dela Cadena Ra, Ghoneim Hr, Colman Rw, Selim Te, Abdel Ghaffar Ha

Publikováno v: The Hematology Journal. 2:371-377

Introduction Preliminary studies have shown that high molecular mass kininogen (HK) inhibits cathepsin G-induced platelet activation. However, the potential mechanism underlying this inhibitory effect remains to be elucidated. Materials and methods S

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https://doi.org/10.1038/sj.thj.6200130

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Autor: El-Sayed HA; Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt., Othman M; Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt. Othman@queensu.ca.; Department of Biomedical and Molecular Sciences, School of Medicine, Queen's University, Kingston, ON, Canada. Othman@queensu.ca.; School of Baccalaureate Nursing, St Lawrence College, Kingston, ON, Canada. Othman@queensu.ca., Azzam H; Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt., Bucciol R; Department of Biomedical and Molecular Sciences, School of Medicine, Queen's University, Kingston, ON, Canada., Ebrahim MA; Oncology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt., El-Agdar MAMA; Oncology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt., Tera Y; Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.; Department of Biomedical and Molecular Sciences, School of Medicine, Queen's University, Kingston, ON, Canada., Sakr DH; Oncology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt., Ghoneim HR; Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt., Selim TE; Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

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High molecular mass kininogen inhibits cathepsin G-induced platelet activation by forming a complex with cathepsin G.

Autor: Selim TE; Hematology Unit, Clinical Pathology Department, Al-Mansoura Faculty of Medicine, Al-Mansoura, Egypt., Ghoneim HR, Abdel Ghaffar HA, Colman RW, Dela Cadena RA

Publikováno v: The hematology journal : the official journal of the European Haematology Association [Hematol J] 2001; Vol. 2 (6), pp. 371-7.