Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Gholamreza Hassanzadeh Ghassabeh"'
Autor:
Charlotte Vanmarsenille, Inés Díaz del Olmo, Jelle Elseviers, Gholamreza Hassanzadeh Ghassabeh, Kristof Moonens, Didier Vertommen, An Martel, Freddy Haesebrouck, Frank Pasmans, Jean-Pierre Hernalsteens, Henri De Greve
Publikováno v:
Veterinary Research, Vol 48, Iss 1, Pp 1-14 (2017)
Abstract Campylobacter infections are among the most prevalent foodborne infections in humans, resulting in a massive disease burden worldwide. Broilers have been identified as the major source of campylobacteriosis and reducing Campylobacter loads i
Externí odkaz:
https://doaj.org/article/8fe69ed226834a18aad8d214d3401ea9
Autor:
Ivana Jovčevska, Neja Zupanec, Nina Kočevar, Daniela Cesselli, Neža Podergajs, Clara Limbaeck Stokin, Michael P Myers, Serge Muyldermans, Gholamreza Hassanzadeh Ghassabeh, Helena Motaln, Maria Elisabetta Ruaro, Evgenia Bourkoula, Tamara Lah Turnšek, Radovan Komel
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113688 (2014)
Malignant gliomas are among the rarest brain tumours, and they have the worst prognosis. Grade IV astrocytoma, known as glioblastoma multiforme (GBM), is a highly lethal disease where the standard therapies of surgery, followed by radiation and chemo
Externí odkaz:
https://doaj.org/article/7e08ee89d22f40f7aeffb38bf8a2e136
Autor:
Benoit Stijlemans, Patrick De Baetselier, Inge Van Molle, Laurence Lecordier, Erika Hendrickx, Ema Romão, Cécile Vincke, Wendy Baetens, Steve Schoonooghe, Gholamreza Hassanzadeh-Ghassabeh, Hannelie Korf, Marie Wallays, Joar E. Pinto Torres, David Perez-Morga, Lea Brys, Oscar Campetella, María S. Leguizamón, Mathieu Claes, Sarah Hendrickx, Dorien Mabille, Guy Caljon, Han Remaut, Kim Roelants, Stefan Magez, Jo A. Van Ginderachter, Carl De Trez
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Human African trypanosomiasis or sleeping sickness, caused by the protozoan parasite Trypanosoma brucei, is characterized by the manipulation of the host’s immune response to ensure parasite invasion and persistence. Uncovering key molecul
Externí odkaz:
https://doaj.org/article/246f0d22755a498bb72fe9a96e853695
Autor:
Tobias Kromann-Hansen, Eva Louise Lange, Hans Peter Sørensen, Gholamreza Hassanzadeh-Ghassabeh, Mingdong Huang, Jan K. Jensen, Serge Muyldermans, Paul J. Declerck, Elizabeth A. Komives, Peter A. Andreasen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Although trypsin-like serine proteases have flexible surface-exposed loops and are known to adopt higher and lower activity conformations, structural determinants for the different conformations have remained largely obscure. The trypsin-lik
Externí odkaz:
https://doaj.org/article/409897e4334a4c2c81d516f9a73f9d64
Autor:
Jonathan R. Hart, Xiao Liu, Chen Pan, Anyi Liang, Lynn Ueno, Yingna Xu, Alexandra Quezada, Xinyu Zou, Su Yang, Qingtong Zhou, Steve Schoonooghe, Gholamreza Hassanzadeh-Ghassabeh, Tian Xia, Wenqing Shui, Dehua Yang, Peter K. Vogt, Ming-Wei Wang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(38)
Nanobodies and chemical cross-linking were used to gain information on the identity and positions of flexible domains of PI3Kα. The application of chemical cross-linking mass spectrometry (CXMS) facilitated the identification of the p85 domains BH,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55133b6f8776690dcbfd4a081e658996
https://pubmed.ncbi.nlm.nih.gov/36095215
https://pubmed.ncbi.nlm.nih.gov/36095215
Autor:
Idalia Sariego, Serge Muyldermans, Cécile Vincke, Gholamreza Hassanzadeh-Ghassabeh, Francisco Morales-Yánez, Katja Polman
Publikováno v:
Morales-Yanez, F J, Sariego, I, Vincke, C, Hassanzadeh-Ghassabeh, G, Polman, K & Muyldermans, S 2019, ' An innovative approach in the detection of Toxocara canis excretory/secretory antigens using specific nanobodies ', International Journal for Parasitology, vol. 49, no. 8, pp. 635-645 . https://doi.org/10.1016/j.ijpara.2019.03.004
International Journal for Parasitology, 49(8), 635-645. Elsevier Limited
International Journal for Parasitology, 49(8), 635-645. Elsevier Limited
Human toxocariasis is a zoonosis resulting from the migration of larval stages of the dog parasite Toxocara canis into the human paratenic host. Despite its well-known limitations, serology remains the most important tool to diagnose the disease. Our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbea68d2317279b2e3edb24f4b85abb
https://research.vu.nl/en/publications/f95553fe-b4a0-4e9a-88be-981461f519d8
https://research.vu.nl/en/publications/f95553fe-b4a0-4e9a-88be-981461f519d8
Autor:
Naima Abidi, Gholamreza Hassanzadeh-Ghassabeh, Helene Trauchessec, Martine Pugnière, Dimitris P. Xirodimas, Serge Muyldermans
Protein NEDDylation emerges as an important post-translational modification and an attractive target for therapeutic intervention. Modification of NEDD8 onto substrates is finely balanced by the co-ordinated activity of conjugating and deconjugating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13da9b8561038ae2682f2b8111924a3
https://doi.org/10.1101/2020.03.20.999326
https://doi.org/10.1101/2020.03.20.999326
Autor:
Paul Declerck, Emanuela Falcinelli, Alessandro Marturano, Serge Muyldermans, Maarten L. V. Hendrickx, Gholamreza Hassanzadeh-Ghassabeh, Manuela Sebastiano, Giuseppe Guglielmini, Paolo Gresele
Matrix metalloproteinase-2 (MMP-2) is an endopeptidase involved in cardiovascular disease and cancer. To date, no highly selective MMP-2 inhibitors have been identified for potential use in humans. Aim of our work was to apply the nanobody technology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14db8ce248dd7fd028b3a32f739c486
http://hdl.handle.net/11391/1465522
http://hdl.handle.net/11391/1465522
Autor:
Hossein Khanahmad, Reza Mahdian, Sirous Zeinali, Roghaye Arezumand, Mehdi Eavazalipour, Nabiollah Namvar-asl, Hamzeh Rahimi, Reza Ahangari Cohan, Kamran Mansouri, Ali Ramazani, Gholamreza Hassanzadeh-Ghassabeh, Mahdi Behdani, Serge Muyldermans
Publikováno v:
Molecular Immunology. 78:183-192
Placental growth factor (PlGF), a member of vascular endothelial growth factors (VEGF) family, is considered as an important antigen associated with pathological conditions such as cancer cell growth, and metastasis. PlGF-targeting via nanobody (Nb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9aa3fbe898f32a733eb10b97f3dc9d
https://doi.org/10.1016/j.molimm.2016.09.012
https://doi.org/10.1016/j.molimm.2016.09.012
Autor:
Mingdong Huang, Peter A. Andreasen, Serge Muyldermans, Tobias Kromann-Hansen, Paul Declerck, Kristen Wing Yu Yung, Emil Oldenburg, Jacky Chi Ki Ngo, Gholamreza Hassanzadeh Ghassabeh
Publikováno v:
Kromann-Hansen, T, Oldenburg, E, Yung, K W Y, Ghassabeh, G H, Muyldermans, S, Declerck, P J, Huang, M, Andreasen, P A & Ngo, J C K 2016, ' A Camelid-derived Antibody Fragment Targeting the Active Site of a Serine Protease Balances between Inhibitor and Substrate Behavior ', Journal of Biological Chemistry, vol. 291, pp. 15156-15168 . https://doi.org/10.1074/jbc.M116.732503
A peptide segment that binds the active site of a serine protease in a substrate-like manner may behave like an inhibitor or a substrate. However, there is sparse information on which factors determine the behavior a particular peptide segment will e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3acc25e9f8bb0da5e9a99671876b2651
https://doi.org/10.1074/jbc.m116.732503
https://doi.org/10.1074/jbc.m116.732503