Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Ghmkin, Hassan"'
Autor:
Hideki Minematsu, Said M. Afify, Yuki Sugihara, Ghmkin Hassan, Maram H. Zahra, Akimasa Seno, Masaki Adachi, Masaharu Seno
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Previously, our group has demonstrated establishment of Cancer Stem Cell (CSC) models from stem cells in the presence of conditioned medium of cancer cell lines. In this study, we tried to identify the factors responsible for the induction o
Externí odkaz:
https://doaj.org/article/2dd3be2d767c48678d0e4eb56aa14b91
Autor:
Nguyen Truong Duc Hoang, Ghmkin Hassan, Tomoya Suehiro, Yuichi Mine, Tohru Matsuki, Makiko Fujii
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Malignant mesothelioma (MM) is an aggressive mesothelial cell cancer type linked mainly to asbestos inhalation. MM characterizes by rapid progression and resistance to standard therapeutic modalities such as surgery, chemotherapy,
Externí odkaz:
https://doaj.org/article/12da88bc81a9461497b39d1415fd0281
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Cancer stem cells (CSCs) are suggested to be responsible for drug resistance and aggressive phenotypes of tumors. Mechanisms of CSC induction are still under investigation. Our lab has established a novel method to generate CSCs from iPSCs u
Externí odkaz:
https://doaj.org/article/f52d2c066b714211bfa9ad70628aea8a
Autor:
Yanning Xu, Said M. Afify, Juan Du, Bingbing Liu, Ghmkin Hassan, Qing Wang, Hanbo Li, Yixin Liu, Xiaoying Fu, Zhengmao Zhu, Ling Chen, Masaharu Seno
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Cancer stem cells (CSCs) are capable of continuous proliferation, self-renewal and are proposed to play significant roles in oncogenesis, tumor growth, metastasis and cancer recurrence. We have established a model of CSCs that was originally
Externí odkaz:
https://doaj.org/article/2229408244c74020a7f0428b27bd490b
Autor:
Ghmkin Hassan, Toshiaki Ohara, Said M. Afify, Kazuki Kumon, Maram H. Zahra, Xiaoying Fu, Mohamad Al Kadi, Akimasa Seno, David S. Salomon, Masaharu Seno
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Cancer stem cells (CSCs) are generated under irregular microenvironment in vivo, of which mimic is quite difficult due to the lack of enough information of the factors responsible for cancer initiation. Here, we demonstrated that
Externí odkaz:
https://doaj.org/article/daf6adf4317e48ca892776e146be0047
Autor:
Kazuki Kumon, Said M. Afify, Ghmkin Hassan, Shunsuke Ueno, Sadia Monzur, Hend M. Nawara, Hagar A. Abu Quora, Mona Sheta, Yanning Xu, Xiaoying Fu, Maram H. Zahra, Akimasa Seno, Masaharu Seno
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Cancer stem cells (CSCs) are subpopulations in the malignant tumors that show self-renewal and multilineage differentiation into tumor microenvironment components that drive tumor growth and heterogeneity. In previous studies, our group succ
Externí odkaz:
https://doaj.org/article/94748b8e5a1d4c658dc75ade67ea7e3d
Autor:
Hager Mansour, Ph.D., Said M. Afify, Ph.D., Ghmkin Hassan, Ph.D., Hagar A. Abu Quora, Ph.D., Hend M. Nawara, Ph.D., Maram H. Zahra, Ph.D., Juan Du, Ph.D., Sadia Monzur, Ph.D., Toshiaki Ohara, M.D., Ph.D., Akimasa Seno, PhD, Masaharu Seno, Ph.D.
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 5, Iss , Pp 100062- (2022)
Metastasis is one of the major causes of cancer deaths. However, the mechanisms of cancer cells acquiring aggressiveness and metastatic potential are still under investigation. Although cancer stem cells (CSCs) have been suggested as tumor initiating
Externí odkaz:
https://doaj.org/article/ee1fe0fc410d44f9a94966074602ca1c
Autor:
Ghmkin Hassan, Said M. Afify, Maram H. Zahra, Hend M. Nawara, Kazuki Kumon, Yoshiaki Iwasaki, David S. Salomon, Akimasa Seno, Masaharu Seno
Publikováno v:
Cytotechnology. 75:243-253
Induced pluripotent stem cells (iPSCs) are useful tools for modeling diseases and developing personalized medicine. We have been developing cancer stem cells (CSCs) from iPSCs with conditioned medium (CM) of cancer-derived cells as the mimicry of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ff36a9153d9a8c660271ca46a223204
https://doi.org/10.1007/s10616-023-00575-1
https://doi.org/10.1007/s10616-023-00575-1
Publikováno v:
Cellular & Molecular Biology Letters, Vol 23, Iss 1, Pp 1-9 (2018)
Abstract Purpose Articular cartilage has a poor capacity for self-repair, and thus still presents a major challenge in orthopedics. Mesenchymal stem cells (MSCs) are multipotent stem cells with the potential to differentiate into chondrocytes in the
Externí odkaz:
https://doaj.org/article/04aa500786ac4efaa9ea22ed870de5d3
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 500 (2021)
Paclitaxel (PTX) is a chemotherapeutical agent commonly used to treat several kinds of cancer. PTX is known as a microtubule-targeting agent with a primary molecular mechanism that disrupts the dynamics of microtubules and induces mitotic arrest and
Externí odkaz:
https://doaj.org/article/904619f709ce416c99780c7a258f5689