Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ghjuvan'Ghjacumu Shackleford"'
Autor:
Ghjuvan'Ghjacumu Shackleford, Leandro N Marziali, Yo Sasaki, Anke Claessens, Cinzia Ferri, Nadav I Weinstock, Alexander M Rossor, Nicholas J Silvestri, Emma R Wilson, Edward Hurley, Grahame J Kidd, Senthilvelan Manohar, Dalian Ding, Richard J Salvi, M Laura Feltri, Maurizio D'Antonio, Lawrence Wrabetz
Publikováno v:
PLoS Genetics, Vol 18, Iss 11, p e1010477 (2022)
Myelin is essential for rapid nerve impulse propagation and axon protection. Accordingly, defects in myelination or myelin maintenance lead to secondary axonal damage and subsequent degeneration. Studies utilizing genetic (CNPase-, MAG-, and PLP-null
Externí odkaz:
https://doaj.org/article/3727869bf2534264a552e58bc6edf603
Autor:
Eric Pasmant, Charbel Massaad, Ivan Bièche, Béatrice Parfait, Pierre Wolkenstein, Dominique Vidaud, Michel Vidaud, Laurent Lantieri, Benoît Terris, Frédérique Larousserie, Laurence Valeyrie-Allanore, Thomas De Raedt, Didier Borderie, Mikael Hivelin, Valérie Dumaine, Karen Leroy, François Lallemand, Jennifer Varin, Nicolas Ortonne, Ingrid Laurendeau, Julien Masliah-Planchon, Ghjuvan'Ghjacumu Shackleford, Armelle Luscan
PDF file 97K, List of the 89 Wnt pathway selected genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c71914fd0e5e0313f5e75ee0634e9f
https://doi.org/10.1158/1078-0432.22448334
https://doi.org/10.1158/1078-0432.22448334
Autor:
Eric Pasmant, Charbel Massaad, Ivan Bièche, Béatrice Parfait, Pierre Wolkenstein, Dominique Vidaud, Michel Vidaud, Laurent Lantieri, Benoît Terris, Frédérique Larousserie, Laurence Valeyrie-Allanore, Thomas De Raedt, Didier Borderie, Mikael Hivelin, Valérie Dumaine, Karen Leroy, François Lallemand, Jennifer Varin, Nicolas Ortonne, Ingrid Laurendeau, Julien Masliah-Planchon, Ghjuvan'Ghjacumu Shackleford, Armelle Luscan
PDF file 161K, A simplified representation of the three different Wnt signalling pathways: the canonical pathway, the planar cell polarity pathway, and the Wnt/calcium pathway. In the absence of Wnt ligand, the 'destruction complex' composed of the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a29ff1ec3ec93231171e9ca3e6a930
https://doi.org/10.1158/1078-0432.22448346
https://doi.org/10.1158/1078-0432.22448346
Autor:
Eric Pasmant, Charbel Massaad, Ivan Bièche, Béatrice Parfait, Pierre Wolkenstein, Dominique Vidaud, Michel Vidaud, Laurent Lantieri, Benoît Terris, Frédérique Larousserie, Laurence Valeyrie-Allanore, Thomas De Raedt, Didier Borderie, Mikael Hivelin, Valérie Dumaine, Karen Leroy, François Lallemand, Jennifer Varin, Nicolas Ortonne, Ingrid Laurendeau, Julien Masliah-Planchon, Ghjuvan'Ghjacumu Shackleford, Armelle Luscan
Purpose: The hallmark of neurofibromatosis type 1 (NF1) is the onset of dermal or plexiform neurofibromas, mainly composed of Schwann cells. Plexiform neurofibromas can transform into malignant peripheral nerve sheath tumors (MPNST) that are resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d89ab9b797fb6438f83d854fbc7c9d
https://doi.org/10.1158/1078-0432.c.6521370
https://doi.org/10.1158/1078-0432.c.6521370
Autor:
Ghjuvan’Ghjacumu Shackleford, Leandro N. Marziali, Yo Sasaki, Nadav I. Weinstock, Alexander M. Rossor, Nicholas J. Silvestri, Emma R. Wilson, Edward Hurley, Grahame J. Kidd, Senthilvelan Manohar, Dalian Ding, Richard J. Salvi, M. Laura Feltri, Maurizio D’Antonio, Lawrence Wrabetz
Myelin is essential for rapid nerve impulse propagation and axon protection. Accordingly, defects in myelination or myelin maintenance lead to secondary axonal damage and subsequent degeneration. Studies utilizing genetic (CNPase-, MAG-, and PLP-null
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbf50a0d0bcd3a0490fe49db2eeb787e
https://doi.org/10.1101/2022.05.09.491190
https://doi.org/10.1101/2022.05.09.491190
Autor:
Delphine Meffre, Charbel Massaad, Philippe Liere, Julien Grenier, Joelle Makoukji, Ghjuvan’Ghjacumu Shackleford
Publikováno v:
Biochemical Pharmacology. 175:113892
Autor:
Sophie Belin, Francesca Ornaghi, Ghjuvan’Ghjacumu Shackleford, Jie Wang, Cristina Scapin, Camila Lopez-Anido, Nicholas Silvestri, Neil Robertson, Courtney Williamson, Akihiro Ishii, Carla Taveggia, John Svaren, Rashmi Bansal, Markus H Schwab, Klaus Nave, Pietro Fratta, Maurizio D’Antonio, Yannick Poitelon, M Laura Feltri, Lawrence Wrabetz
Publikováno v:
Human molecular genetics. 28(10)
Myelin sheath thickness is precisely regulated and essential for rapid propagation of action potentials along myelinated axons. In the peripheral nervous system, extrinsic signals from the axonal protein neuregulin 1 (NRG1) type III regulate Schwann
Autor:
Maurizio D'Antonio, Ghjuvan'Ghjacumu Shackleford, Pietro Fratta, John Svaren, Courtney Williamson, Lawrence Wrabetz, Francesca Ornaghi, Markus H. Schwab, Maria Laura Feltri, Yannick Poitelon, Carla Taveggia, Camila Lopez-Anido, Nicholas Silvestri, Rashmi Bansal, Jie Wang, Cristina Scapin, Klaus-Armin Nave, Neil M. Robertson, Akihiro Ishii, Belin Sophie
Myelin sheath thickness is precisely regulated and essential for rapid propagation of action potentials along myelinated axons. In the peripheral nervous system, extrinsic signals from the axonal protein neuregulin 1 type III regulate Schwann cell fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49545d29cf55eb7d23774678d8aefa5f
Autor:
Ludmila Juricek, Charbel Massaad, Frédéric Charbonnier, Mehdi Hichor, Ingrid Laurendeau, Eric Pasmant, Etienne-Emile Baulieu, Ivan Bièche, Marc Herbin, Xavier Coumoul, Frédérique Larousserie, Mathieu Beraneck, Laure Weill, Nicolas Ortonne, Nirmal Kumar Sampathkumar, Ghjuvan’Ghjacumu Shackleford, Delphine Meffre, Aline Chevallier
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (6), pp.E1319-E1328. ⟨10.1073/pnas.1715999115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (6), pp.E1319-E1328. ⟨10.1073/pnas.1715999115⟩
International audience; Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor involved in xenobiotic metabolism. Plexiform neurofibromas (PNFs) can transform into malignant peripheral nerve sheath tumors (MPNSTs) that are resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415b8b9263a900cb2b52ff1ba86622e7
https://hal.archives-ouvertes.fr/hal-02110942
https://hal.archives-ouvertes.fr/hal-02110942
Autor:
Ghjuvan’Ghjacumu Shackleford, Julien Grenier, Delphine Meffre, Charbel Massaad, Philippe Liere, Joelle Makoukji
Publikováno v:
Biochemical Pharmacology. 86:106-114
Oxysterols are reactive molecules generated by the oxidation of cholesterol. Their implication in cholesterol homeostasis and in the progression of neurodegenerative disorders is well known. Here, we study the role of oxysterols and their nuclear rec