Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ghislaine Schweizer-Groyer"'
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 122:149-158
The contribution of the two corticosteroid (mineralocorticoid and glucocorticoid) receptor (MR and GR) pathways to the function and regeneration of the sciatic nerve was investigated. We found that the corticosterone-inactivating enzyme 11β-hydroxys
Autor:
Christelle Girard, Mariano A. Ostuni, Pascale Dufourcq, Sophie Vriz, Freyssinet Jm, Christine Rampon, Mohamed Bouzaffour, Ghislaine Schweizer-Groyer, Jean-Jacques Lacapère
Publikováno v:
The FASEB Journal. 23:4181-4192
The translocator protein (18 kDa) (TSPO), also known as peripheral-type benzodiazepine receptor, is directly or indirectly associated with many biological processes. Although extensively characterized, the specific function of TSPO during development
Publikováno v:
Biochemical Pharmacology. 68:1003-1015
Strong evidence emphasizes the role of the insulin-like growth factor (IGF) system and of type-I IGF receptor (IGF-IR) signalling in tumourigenesis. In this connection: (i) changes in the expression pattern of components of the IGF system (autocrine/
Autor:
Dominique Fortin, André Groyer, Nicole Jibard, Françoise Cadepond, Etienne-Emile Baulieu, Eric Neau, Ghislaine Schweizer-Groyer
Publikováno v:
Journal of Biological Chemistry. 274:11679-11686
In vivo, insulin-like growth factor-binding protein-1 (IGFBP-1) modulates the IGFs' bioavailability and may contribute to their delivery to peripheral tissues. In rat and human hepatocytes, glucocorticoids stimulate IGFBP-1 gene transcription through
Autor:
Xia Meng, Françoise Cadepond, Philippe Leclerc, Krzysztof Rajkowski, Nicole Jibard, Maria-Grazia Catelli, Etienne-Emile Baulieu, Dominique Fortin, Ghislaine Schweizer-Groyer
Publikováno v:
Experimental Cell Research. 247:461-474
The role of the 90-kDa heat shock protein (Hsp90) as a chaperone and its regulatory functions for cellular proteins such as the glucocorticosteroid receptor (GR) depends on the direct interaction of the Hsp90 with the corresponding protein as part of
Autor:
Nicole Jibard, Philippe Leclerc, Xia Meng, Etienne-Emile Baulieu, Krzysztof Rajkowski, Maria-Grazia Catelli, Dominique Fortin, Françoise Cadepond, Ghislaine Schweizer-Groyer, Ki Kang
Publikováno v:
Experimental Cell Research. 242:255-264
The investigation of molecular interactions in whole cells by immunofluorescence was developed recently, based on the targeting of the protein partners to different cellular compartments and analysis of the modifications in their subcellular distribu
Autor:
Ghislaine Schweizer-Groyer, Etienne-Emile Baulieu, Nicole Jibard, I. Segard-Maurel, Nadine Binart, Françoise Cadepond
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 48:361-367
We have developed an in vivo system using coexpression of human glucocorticosteroid receptor (hGR) and chick hsp90α (chsp90) in recombinant virus-infected Sf9 cells to study the formation of hetero-oligomeric complexes. We detected, in the cytosol,
Autor:
Etienne-Emile Baulieu, Nadine Binart, Béatrice Chambraud, Nicole Jibard, I. Segard-Maurel, Françoise Cadepond, Ghislaine Schweizer-Groyer
Publikováno v:
Proceedings of the National Academy of Sciences. 90:10434-10438
Coexpression of the human glucocorticosteroid receptor (hGR) and chicken 90-kDa heat shock protein alpha (chsp90) in recombinant baculovirus-infected Sf9 cells is a system that provides a large quantity of wild-type chsp90-hGR complexes able to bind
Autor:
Ghislaine Schweizer-Groyer, Françoise Cadepond, I. Segard-Maurel, Etienne-Emile Baulieu, Jean-Marie Gasc, Ronald M. Evans, Nicole Jibard, Francine Delahaye
Publikováno v:
Experimental Cell Research. 201:99-108
Nuclear localization of the rat glucocorticosteroid receptor (rGR) transiently expressed in COS-7 cells appears to be mediated by two nuclear localization signals, NL1 and NL2, in a hormone-dependent mechanism. We investigated the intracellular distr
Autor:
Marc Verleye, Françoise Cadepond, Ghislaine Schweizer-Groyer, Jean-Marie Gillardin, Christelle Girard, Etienne-Emile Baulieu, Catherine Lacroix, David H. Adams, Song Liu, Michael Schumacher
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(51)
Peripheral nerves show spontaneous regenerative responses, but recovery after injury or peripheral neuropathies (toxic, diabetic, or chronic inflammatory demyelinating polyneuropathy syndromes) is slow and often incomplete, and at present no efficien