Výsledky vyhledávání - "Ghislaine Leleu"

Didanosine in HIV‐1–Infected Patients Experiencing Failure of Antiretroviral Therapy: A Randomized Placebo‐Controlled Trial

Autor: Laurence Heripret, Ghislaine Leleu, Corinne Merle De Boever, Martine Troccaz, Juliette Pavie, Jean-Michel Molina, Anne-Geneviève Marcelin, Ai Jaguar Study Team

Publikováno v: The Journal of Infectious Diseases. 191:840-847

The antiviral efficacy of didanosine in patients experiencing virological failure is not well known.A total of 168 patients (139 men and 29 women) receiving stable antiretroviral therapy with plasma human immunodeficiency virus type 1 (HIV-1) RNA lev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1dc63d0cd8a63747e1e498bf13073c
https://doi.org/10.1086/428094

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Systemic candidiasis in intensive care units: A multicenter, matched-cohort study

Autor: Philippe Aegerter, Bertrand Guidet, Ghislaine Leleu

Publikováno v: Journal of Critical Care. 17:168-175

Objective: To determine the impact of systemic candidiasis on the mortality and length of hospital stay of intensive care unit (ICU) patients and the associated workload. Design: Multicenter, retrospective, matched-cohort study. Setting: Data were re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0dce2a71fdb0d26d1f59b9a62ddefa7
https://doi.org/10.1053/jcrc.2002.35815

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Unboosted atazanavir-based therapy maintains control of HIV type-1 replication as effectively as a ritonavir-boosted regimen

Autor: Adriano Lazzarin, Sophie Biguenet, Giampiero Carosi, Vadim Pokrovsky, Jade Ghosn, Gilles Pialoux, Jean François Delfraissy, Santiago Moreno, Ghislaine Leleu, Agnes Balogh, Jose Sanz-Moreno, Eric Vandeloise

Publikováno v: Antiviral therapy. 15(7)

Background Triple combination therapy based on a ritonavir (RTV)-boosted protease inhibitor plus two nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) has improved outcomes in HIV type-1 (HIV-1)-infected patients. For patients unable to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de0f93cbd1d6f716577f3d7a98c0d6e
https://pubmed.ncbi.nlm.nih.gov/21041914

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Corticosteroids as Adjunctive Therapy for Severe Pneumocystis carinii Pneumonia in Non-Human Immunodeficiency Virus-Infected Patients: Retrospective Study of 31 Patients

Autor: Christophe Delclaux, Ghislaine Leleu, François Lebargy, Gibba Amraoui, Benoît Schlemmer, Laurent Brochard, Christian Brun-Buisson, Jean-Ralph Zahar

Publikováno v: Clinical Infectious Diseases. 29:670-672

The aim of this retrospective study was to assess whether corticosteroid adjunctive therapy (CAT) could prevent death in immunocompromised patients with severe Pneumocystis carinii pneumonia (PCP) who do not have human immunodeficiency virus (HIV) in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09750d50979efaeb78b8dff13a742711
https://doi.org/10.1086/598651

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Simultaneous analysis of several antiretroviral nucleosides in rat-plasma by high-performance liquid chromatography with UV using acetic acid/hydroxylamine buffer Test of this new volatile medium-pH for HPLC-ESI-MS/MS

Autor: Philippe Morin, Ghislaine Leleu, Luigi A. Agrofoglio, Vincent Bezy, Philippe Couerbe

Publikováno v: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 821(2)

Zalcitabine (ddC), lamivudine (3TC), didanosine (ddI), stavudine (d4T), carbovir (CBV), zidovudine (AZT), tenofovir (PMPA) and its administrated form (tenofovir diisoproxyl fumarate, TDF), are nucleosides currently approved in HIV therapy. To facilit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d250039e3f81faf063bed30dc16b47
https://pubmed.ncbi.nlm.nih.gov/15922678

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Monitoring of didanosine and stavudine intracellular trisphosphorylated anabolite concentrations in HIV-infected patients

Autor: C. Ndeye Toure Kane, Murielle Vray, Ana Canestri, Roland Landman, Henri Benech, Ghislaine Leleu, Mboup S, François Becher, Marie-Helene Prevot, Florent Liegeois

Publikováno v: AIDS (London, England). 18(2)

Objective: To determine the concentrations of intracellular active anabolites of stavudine (d4T) and didanosine (DDI) and their interpatient variability in HIV-infected patients and to explore relationships between plasma and intracellular forms. Met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15809b59ab248c801770bde1fbcdec5
https://pubmed.ncbi.nlm.nih.gov/15075534

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Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study

Autor: Alexandre Mignon, Laurence Arbibe, Marc Delpech, Marie-Reine Losser, Jean-Louis Teboul, Christophe Delclaux, Christine Cheval, Jean-François Dhainaut, Fahrad Heshmati, Florence Riche, Franck Grall, Mehran Monchi, Ghislaine Leleu, Jean-Paul Mira, Alain Cariou

Publikováno v: JAMA. 282(6)

ContextTumor necrosis factor alpha (TNF-α) is believed to be a cytokine central to pathogenesis of septic shock. TNF2, a polymorphism within the TNF-α gene promoter, has been associated with enhanced TNF-α production and negative outcome in some s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd039faa2e2b2e7d8eb39b950e78d08c
https://pubmed.ncbi.nlm.nih.gov/10450722

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