From the RNA-Peptide World: Prebiotic Reaction Conditions Compatible with Lipid Membranes for the Formation of Lipophilic Random Peptides in the Presence of Short Oligonucleotides, and More

Autor: Augustin Lopez, Antoine Vauchez, Ghinwa Ajram, Anastasiia Shvetsova, Gabrielle Leveau, Michele Fiore, Peter Strazewski

Publikováno v: Life, Vol 14, Iss 1, p 108 (2024)

Deciphering the origins of life on a molecular level includes unravelling the numerous interactions that could occur between the most important biomolecules being the lipids, peptides and nucleotides. They were likely all present on the early Earth a

Externí odkaz: https://doaj.org/article/692b58fc4be84f02a3d31751161e057c

The Prebiotic C-Terminal Elongation of Peptides Can Be Initiated by N-Carbamoyl Amino Acids

Autor: Grégoire Danger, Fabrice Duvernay, Jean-Christophe Rossi, Ghinwa Ajram, Laurent Boiteau, Robert Pascal, Ninette Abou Mrad

Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2017, 23 (31), pp.7418-7421. ⟨10.1002/chem.201700702⟩
Chemistry-A European Journal, 2017, 23 (31), pp.7418-7421. ⟨10.1002/chem.201700702⟩

International audience; The formation of peptides upon 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC)-promoted activation of N-carbamoylamino acids (CAA), was considered in the scope of our recent works on carbodiimide promoted C-terminus elong

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60516b369eb89b1affb17d710e745887
https://pubmed.ncbi.nlm.nih.gov/28378889