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A comprehensive update of siRNA delivery design strategies for targeted and effective gene silencing in gene therapy and other applications

Autor: Abosalha, Ahmed Khaled, Ahmad, Waqar, Boyajian, Jacqueline, Islam, Paromita, Ghebretatios, Merry, Schaly, Sabrina, Thareja, Rahul, Arora, Karan, Prakash, Satya

Publikováno v: Expert Opinion on Drug Discovery; February 2023, Vol. 18 Issue: 2 p149-161, 13p

C-CASE 2023: Promoting Excellence in Surgical Education: Canadian Conference for the Advancement of Surgical Education, Oct. 12-13, 2023, Montréal, Quebec.

Autor: Sioufi J; From the Faculty of Medicine and Health Sciences, McGill University, Montréal, Que.; From the Faculty of Medicine and Health Sciences, McGill University, Montréal, Que. (Moussa, Subasri, Fakih, Islam); and the Shriners Hospital for Children and Division of Orthopaedics, Montreal Children's Hospital, Montréal, Que. (Hamdy)., Hall B; From the Faculty of Medicine and Health Sciences, McGill University, Montréal, Que.; From the Faculty of Medicine and Health Sciences, McGill University, Montréal, Que. (Moussa, Subasri, Fakih, Islam); and the Shriners Hospital for Children and Division of Orthopaedics, Montreal Children's Hospital, Montréal, Que. (Hamdy)., Antel R; From the Faculty of Medicine and Health Sciences, McGill University, Montréal, Que.; From the Faculty of Medicine and Health Sciences, McGill University, Montréal, Que. (Moussa, Subasri, Fakih, Islam); and the Shriners Hospital for Children and Division of Orthopaedics, Montreal Children's Hospital, Montréal, Que. (Hamdy)., Moussa S, Subasri M, Fakih M, Islam N, Hamdy RC, Chopra S; From McMaster University, Hamilton, Ont. (Chopra, Keuhl, Bassilious, Sherbino, Bilgic); and McGill University, Montreal, Que. (Harley)., Harley JM; From McMaster University, Hamilton, Ont. (Chopra, Keuhl, Bassilious, Sherbino, Bilgic); and McGill University, Montreal, Que. (Harley)., Keuhl A; From McMaster University, Hamilton, Ont. (Chopra, Keuhl, Bassilious, Sherbino, Bilgic); and McGill University, Montreal, Que. (Harley)., Bassilious E; From McMaster University, Hamilton, Ont. (Chopra, Keuhl, Bassilious, Sherbino, Bilgic); and McGill University, Montreal, Que. (Harley)., Sherbino J; From McMaster University, Hamilton, Ont. (Chopra, Keuhl, Bassilious, Sherbino, Bilgic); and McGill University, Montreal, Que. (Harley)., Bilgic E; From McMaster University, Hamilton, Ont. (Chopra, Keuhl, Bassilious, Sherbino, Bilgic); and McGill University, Montreal, Que. (Harley)., Bondok MS; From the Cumming School of Medicine, University of Calgary, Calgary, Alb. (M.S. Bondok); the UBC Faculty of Medicine, University of British Columbia, Vancouver, B.C. (M. Bondok); the Faculty of Medicine, University of Ottawa, Ottawa, Ont. (Martel); and the Department of Ophthalmology, School of Medicine, Queen's University, Kingston, Ont. (Law).; From McGill University, Montréal, Que., Bondok M; From the Cumming School of Medicine, University of Calgary, Calgary, Alb. (M.S. Bondok); the UBC Faculty of Medicine, University of British Columbia, Vancouver, B.C. (M. Bondok); the Faculty of Medicine, University of Ottawa, Ottawa, Ont. (Martel); and the Department of Ophthalmology, School of Medicine, Queen's University, Kingston, Ont. (Law).; From McGill University, Montréal, Que., Martel L; From the Cumming School of Medicine, University of Calgary, Calgary, Alb. (M.S. Bondok); the UBC Faculty of Medicine, University of British Columbia, Vancouver, B.C. (M. Bondok); the Faculty of Medicine, University of Ottawa, Ottawa, Ont. (Martel); and the Department of Ophthalmology, School of Medicine, Queen's University, Kingston, Ont. (Law).; From McGill University, Montréal, Que., Law C; From the Cumming School of Medicine, University of Calgary, Calgary, Alb. (M.S. Bondok); the UBC Faculty of Medicine, University of British Columbia, Vancouver, B.C. (M. Bondok); the Faculty of Medicine, University of Ottawa, Ottawa, Ont. (Martel); and the Department of Ophthalmology, School of Medicine, Queen's University, Kingston, Ont. (Law).; From McGill University, Montréal, Que., Posel N, Fleiszer D, Daud A; From the University of Toronto, Toronto, Ont., Hauer T; From the University of Toronto, Toronto, Ont., Carr-Pries N; From the University of Toronto, Toronto, Ont., Hali K; From the University of Toronto, Toronto, Ont., Wolfstadt J; From the University of Toronto, Toronto, Ont., Ferguson P; From the University of Toronto, Toronto, Ont., Ghasroddashti A; From Queen's University, Kingston, Ont., Sorefan-Mangou F; From Queen's University, Kingston, Ont., Del Fernandes R; From Queen's University, Kingston, Ont., Williams E; From Queen's University, Kingston, Ont., Choi K; From Queen's University, Kingston, Ont., Zevin B; From Queen's University, Kingston, Ont., Patterson ED; From Queen's University, Kingston, Ont.; From the Faculty of Medicine, University of British Columbia, Vancouver, B.C. (Bondok); the Faculty of Medicine, University of Ottawa, Ottawa, Ont. (Ghanmi, Saddiki, Lefebvre, Berthelot, Dion, Raymond, Seguin, Sekhavati, Islam); the Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ont. (Etherington, Boet); the Department of Anesthesiology & Pain Medicine, The Ottawa Hospital, Ottawa, Ont (Boet); and the Department of Innovation in Medical Education, University of Ottawa, Ottawa, Ont. (Boet)., Kirupaharan S; From Queen's University, Kingston, Ont.; From the Faculty of Medicine, University of British Columbia, Vancouver, B.C. (Bondok); the Faculty of Medicine, University of Ottawa, Ottawa, Ont. (Ghanmi, Saddiki, Lefebvre, Berthelot, Dion, Raymond, Seguin, Sekhavati, Islam); the Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ont. (Etherington, Boet); the Department of Anesthesiology & Pain Medicine, The Ottawa Hospital, Ottawa, Ont (Boet); and the Department of Innovation in Medical Education, University of Ottawa, Ottawa, Ont. (Boet)., Mann S; From Queen's University, Kingston, Ont.; From the Faculty of Medicine, University of British Columbia, Vancouver, B.C. (Bondok); the Faculty of Medicine, University of Ottawa, Ottawa, Ont. (Ghanmi, Saddiki, Lefebvre, Berthelot, Dion, Raymond, Seguin, Sekhavati, Islam); the Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ont. (Etherington, Boet); the Department of Anesthesiology & Pain Medicine, The Ottawa Hospital, Ottawa, Ont (Boet); and the Department of Innovation in Medical Education, University of Ottawa, Ottawa, Ont. (Boet)., Winthrop A; From Queen's University, Kingston, Ont.; From the Faculty of Medicine, University of British Columbia, Vancouver, B.C. (Bondok); the Faculty of Medicine, University of Ottawa, Ottawa, Ont. (Ghanmi, Saddiki, Lefebvre, Berthelot, Dion, Raymond, Seguin, Sekhavati, Islam); the Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ont. (Etherington, Boet); the Department of Anesthesiology & Pain Medicine, The Ottawa Hospital, Ottawa, Ont (Boet); and the Department of Innovation in Medical Education, University of Ottawa, Ottawa, Ont. (Boet)., Zevin B; From Queen's University, Kingston, Ont.; From the Faculty of Medicine, University of British Columbia, Vancouver, B.C. (Bondok); the Faculty of Medicine, University of Ottawa, Ottawa, Ont. (Ghanmi, Saddiki, Lefebvre, Berthelot, Dion, Raymond, Seguin, Sekhavati, Islam); the Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ont. (Etherington, Boet); the Department of Anesthesiology & Pain Medicine, The Ottawa Hospital, Ottawa, Ont (Boet); and the Department of Innovation in Medical Education, University of Ottawa, Ottawa, Ont. (Boet)., Bondok M, Ghanmi N, Etherington C, Saddiki Y, Lefebvre I, Berthelot P, Dion PM, Raymond B, Seguin J, Sekhavati P, Islam S, Boet S, Tee T; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que. (Tee, Pachchigar, Tarabay, Yilmaz, Abou Hamdan, Agu, Almansouri, Del Maestro); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Del Maestro); the University of Montreal Health Centre, Montréal, Que. (Tarabay); and the Simulation, Affect, Innovation, Learning, and Surgery Laboratory, Montreal Neurological Institute, McGill University, Montréal, Que. (Harley)., Pachchigar P; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que. (Tee, Pachchigar, Tarabay, Yilmaz, Abou Hamdan, Agu, Almansouri, Del Maestro); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Del Maestro); the University of Montreal Health Centre, Montréal, Que. (Tarabay); and the Simulation, Affect, Innovation, Learning, and Surgery Laboratory, Montreal Neurological Institute, McGill University, Montréal, Que. (Harley)., Tarabay B; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que. (Tee, Pachchigar, Tarabay, Yilmaz, Abou Hamdan, Agu, Almansouri, Del Maestro); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Del Maestro); the University of Montreal Health Centre, Montréal, Que. (Tarabay); and the Simulation, Affect, Innovation, Learning, and Surgery Laboratory, Montreal Neurological Institute, McGill University, Montréal, Que. (Harley)., Yilmaz R; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que. (Tee, Pachchigar, Tarabay, Yilmaz, Abou Hamdan, Agu, Almansouri, Del Maestro); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Del Maestro); the University of Montreal Health Centre, Montréal, Que. (Tarabay); and the Simulation, Affect, Innovation, Learning, and Surgery Laboratory, Montreal Neurological Institute, McGill University, Montréal, Que. (Harley)., Hamdan NA; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que. (Tee, Pachchigar, Tarabay, Yilmaz, Abou Hamdan, Agu, Almansouri, Del Maestro); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Del Maestro); the University of Montreal Health Centre, Montréal, Que. (Tarabay); and the Simulation, Affect, Innovation, Learning, and Surgery Laboratory, Montreal Neurological Institute, McGill University, Montréal, Que. (Harley)., Agu C; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que. (Tee, Pachchigar, Tarabay, Yilmaz, Abou Hamdan, Agu, Almansouri, Del Maestro); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Del Maestro); the University of Montreal Health Centre, Montréal, Que. (Tarabay); and the Simulation, Affect, Innovation, Learning, and Surgery Laboratory, Montreal Neurological Institute, McGill University, Montréal, Que. (Harley)., Almansouri A; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que. (Tee, Pachchigar, Tarabay, Yilmaz, Abou Hamdan, Agu, Almansouri, Del Maestro); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Del Maestro); the University of Montreal Health Centre, Montréal, Que. (Tarabay); and the Simulation, Affect, Innovation, Learning, and Surgery Laboratory, Montreal Neurological Institute, McGill University, Montréal, Que. (Harley)., Harley J; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que. (Tee, Pachchigar, Tarabay, Yilmaz, Abou Hamdan, Agu, Almansouri, Del Maestro); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Del Maestro); the University of Montreal Health Centre, Montréal, Que. (Tarabay); and the Simulation, Affect, Innovation, Learning, and Surgery Laboratory, Montreal Neurological Institute, McGill University, Montréal, Que. (Harley)., Del Maestro R; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que. (Tee, Pachchigar, Tarabay, Yilmaz, Abou Hamdan, Agu, Almansouri, Del Maestro); the Department of Neurology and Neurosurgery, McGill University, Montréal, Que. (Del Maestro); the University of Montreal Health Centre, Montréal, Que. (Tarabay); and the Simulation, Affect, Innovation, Learning, and Surgery Laboratory, Montreal Neurological Institute, McGill University, Montréal, Que. (Harley)., Bondok M; From the Faculty of Medicine, University of British Columbia, Vancouver, B.C. (M. Bondok); the Cumming School of Medicine, University of Calgary, Calgary, Alb. (M.S. Bondok); the Faculty of Medicine and Health Sciences, McGill University, Montréal, Que. (Nguyen); the Department of Ophthalmology, Queen's University, Kingston, Ont. (Law); the Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, B.C. (Nathoo); the Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont. (Bakshi); the Division of Ophthalmology, McMaster University, Hamilton, Ont. (Ahuja); and the Department of Ophthalmology and Visual Sciences, Aga Khan University, Karachi, Pakistan (Damji)., Bondok MS; From the Faculty of Medicine, University of British Columbia, Vancouver, B.C. (M. Bondok); the Cumming School of Medicine, University of Calgary, Calgary, Alb. (M.S. Bondok); the Faculty of Medicine and Health Sciences, McGill University, Montréal, Que. (Nguyen); the Department of Ophthalmology, Queen's University, Kingston, Ont. (Law); the Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, B.C. (Nathoo); the Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont. (Bakshi); the Division of Ophthalmology, McMaster University, Hamilton, Ont. (Ahuja); and the Department of Ophthalmology and Visual Sciences, Aga Khan University, Karachi, Pakistan (Damji)., Nguyen AX; From the Faculty of Medicine, University of British Columbia, Vancouver, B.C. (M. Bondok); the Cumming School of Medicine, University of Calgary, Calgary, Alb. (M.S. Bondok); the Faculty of Medicine and Health Sciences, McGill University, Montréal, Que. (Nguyen); the Department of Ophthalmology, Queen's University, Kingston, Ont. (Law); the Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, B.C. (Nathoo); the Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont. (Bakshi); the Division of Ophthalmology, McMaster University, Hamilton, Ont. (Ahuja); and the Department of Ophthalmology and Visual Sciences, Aga Khan University, Karachi, Pakistan (Damji)., Law C; From the Faculty of Medicine, University of British Columbia, Vancouver, B.C. (M. Bondok); the Cumming School of Medicine, University of Calgary, Calgary, Alb. (M.S. Bondok); the Faculty of Medicine and Health Sciences, McGill University, Montréal, Que. (Nguyen); the Department of Ophthalmology, Queen's University, Kingston, Ont. (Law); the Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, B.C. (Nathoo); the Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont. (Bakshi); the Division of Ophthalmology, McMaster University, Hamilton, Ont. (Ahuja); and the Department of Ophthalmology and Visual Sciences, Aga Khan University, Karachi, Pakistan (Damji)., Nathoo N; From the Faculty of Medicine, University of British Columbia, Vancouver, B.C. (M. Bondok); the Cumming School of Medicine, University of Calgary, Calgary, Alb. (M.S. Bondok); the Faculty of Medicine and Health Sciences, McGill University, Montréal, Que. (Nguyen); the Department of Ophthalmology, Queen's University, Kingston, Ont. (Law); the Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, B.C. (Nathoo); the Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont. (Bakshi); the Division of Ophthalmology, McMaster University, Hamilton, Ont. (Ahuja); and the Department of Ophthalmology and Visual Sciences, Aga Khan University, Karachi, Pakistan (Damji)., Bakshi N; From the Faculty of Medicine, University of British Columbia, Vancouver, B.C. (M. Bondok); the Cumming School of Medicine, University of Calgary, Calgary, Alb. (M.S. Bondok); the Faculty of Medicine and Health Sciences, McGill University, Montréal, Que. (Nguyen); the Department of Ophthalmology, Queen's University, Kingston, Ont. (Law); the Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, B.C. (Nathoo); the Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont. (Bakshi); the Division of Ophthalmology, McMaster University, Hamilton, Ont. (Ahuja); and the Department of Ophthalmology and Visual Sciences, Aga Khan University, Karachi, Pakistan (Damji)., Ahuja N; From the Faculty of Medicine, University of British Columbia, Vancouver, B.C. (M. Bondok); the Cumming School of Medicine, University of Calgary, Calgary, Alb. (M.S. Bondok); the Faculty of Medicine and Health Sciences, McGill University, Montréal, Que. (Nguyen); the Department of Ophthalmology, Queen's University, Kingston, Ont. (Law); the Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, B.C. (Nathoo); the Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont. (Bakshi); the Division of Ophthalmology, McMaster University, Hamilton, Ont. (Ahuja); and the Department of Ophthalmology and Visual Sciences, Aga Khan University, Karachi, Pakistan (Damji)., Damji KF; From the Faculty of Medicine, University of British Columbia, Vancouver, B.C. (M. Bondok); the Cumming School of Medicine, University of Calgary, Calgary, Alb. (M.S. Bondok); the Faculty of Medicine and Health Sciences, McGill University, Montréal, Que. (Nguyen); the Department of Ophthalmology, Queen's University, Kingston, Ont. (Law); the Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, B.C. (Nathoo); the Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont. (Bakshi); the Division of Ophthalmology, McMaster University, Hamilton, Ont. (Ahuja); and the Department of Ophthalmology and Visual Sciences, Aga Khan University, Karachi, Pakistan (Damji)., Grewal K; From McGill University, Montréal, Que. (Grewal, Azher, Moreno, Wiseman, Fried, Lajoie, Sun, Harley); the University of Essex, Colchester, UK (Pekrun); the Ludwig Maximilian University of Munich, Munich, Germany (Pekrun); the Australian Catholic University, Sydney, Australia (Pekrun); the University of Toronto, Toronto, Ont. (Brydges); the University of Victoria, Victoria, B.C. (Hadwin); the McGill University Health Centre for Interprofessional Simulation, McGill University, Montréal, Que. (Khalil); and the Research Institute of the McGill University Health Centre, McGill University, Montréal, Que. (Harley)., Azher S; From McGill University, Montréal, Que. (Grewal, Azher, Moreno, Wiseman, Fried, Lajoie, Sun, Harley); the University of Essex, Colchester, UK (Pekrun); the Ludwig Maximilian University of Munich, Munich, Germany (Pekrun); the Australian Catholic University, Sydney, Australia (Pekrun); the University of Toronto, Toronto, Ont. (Brydges); the University of Victoria, Victoria, B.C. (Hadwin); the McGill University Health Centre for Interprofessional Simulation, McGill University, Montréal, Que. (Khalil); and the Research Institute of the McGill University Health Centre, McGill University, Montréal, Que. (Harley)., Moreno M; From McGill University, Montréal, Que. (Grewal, Azher, Moreno, Wiseman, Fried, Lajoie, Sun, Harley); the University of Essex, Colchester, UK (Pekrun); the Ludwig Maximilian University of Munich, Munich, Germany (Pekrun); the Australian Catholic University, Sydney, Australia (Pekrun); the University of Toronto, Toronto, Ont. (Brydges); the University of Victoria, Victoria, B.C. (Hadwin); the McGill University Health Centre for Interprofessional Simulation, McGill University, Montréal, Que. (Khalil); and the Research Institute of the McGill University Health Centre, McGill University, Montréal, Que. (Harley)., Pekrun R; From McGill University, Montréal, Que. (Grewal, Azher, Moreno, Wiseman, Fried, Lajoie, Sun, Harley); the University of Essex, Colchester, UK (Pekrun); the Ludwig Maximilian University of Munich, Munich, Germany (Pekrun); the Australian Catholic University, Sydney, Australia (Pekrun); the University of Toronto, Toronto, Ont. (Brydges); the University of Victoria, Victoria, B.C. (Hadwin); the McGill University Health Centre for Interprofessional Simulation, McGill University, Montréal, Que. (Khalil); and the Research Institute of the McGill University Health Centre, McGill University, Montréal, Que. (Harley)., Wiseman J; From McGill University, Montréal, Que. (Grewal, Azher, Moreno, Wiseman, Fried, Lajoie, Sun, Harley); the University of Essex, Colchester, UK (Pekrun); the Ludwig Maximilian University of Munich, Munich, Germany (Pekrun); the Australian Catholic University, Sydney, Australia (Pekrun); the University of Toronto, Toronto, Ont. (Brydges); the University of Victoria, Victoria, B.C. (Hadwin); the McGill University Health Centre for Interprofessional Simulation, McGill University, Montréal, Que. (Khalil); and the Research Institute of the McGill University Health Centre, McGill University, Montréal, Que. (Harley)., Fried GM; From McGill University, Montréal, Que. (Grewal, Azher, Moreno, Wiseman, Fried, Lajoie, Sun, Harley); the University of Essex, Colchester, UK (Pekrun); the Ludwig Maximilian University of Munich, Munich, Germany (Pekrun); the Australian Catholic University, Sydney, Australia (Pekrun); the University of Toronto, Toronto, Ont. (Brydges); the University of Victoria, Victoria, B.C. (Hadwin); the McGill University Health Centre for Interprofessional Simulation, McGill University, Montréal, Que. (Khalil); and the Research Institute of the McGill University Health Centre, McGill University, Montréal, Que. (Harley)., Lajoie S; From McGill University, Montréal, Que. (Grewal, Azher, Moreno, Wiseman, Fried, Lajoie, Sun, Harley); the University of Essex, Colchester, UK (Pekrun); the Ludwig Maximilian University of Munich, Munich, Germany (Pekrun); the Australian Catholic University, Sydney, Australia (Pekrun); the University of Toronto, Toronto, Ont. (Brydges); the University of Victoria, Victoria, B.C. (Hadwin); the McGill University Health Centre for Interprofessional Simulation, McGill University, Montréal, Que. (Khalil); and the Research Institute of the McGill University Health Centre, McGill University, Montréal, Que. (Harley)., Brydges R; From McGill University, Montréal, Que. (Grewal, Azher, Moreno, Wiseman, Fried, Lajoie, Sun, Harley); the University of Essex, Colchester, UK (Pekrun); the Ludwig Maximilian University of Munich, Munich, Germany (Pekrun); the Australian Catholic University, Sydney, Australia (Pekrun); the University of Toronto, Toronto, Ont. (Brydges); the University of Victoria, Victoria, B.C. (Hadwin); the McGill University Health Centre for Interprofessional Simulation, McGill University, Montréal, Que. (Khalil); and the Research Institute of the McGill University Health Centre, McGill University, Montréal, Que. (Harley)., Hadwin A; From McGill University, Montréal, Que. (Grewal, Azher, Moreno, Wiseman, Fried, Lajoie, Sun, Harley); the University of Essex, Colchester, UK (Pekrun); the Ludwig Maximilian University of Munich, Munich, Germany (Pekrun); the Australian Catholic University, Sydney, Australia (Pekrun); the University of Toronto, Toronto, Ont. (Brydges); the University of Victoria, Victoria, B.C. (Hadwin); the McGill University Health Centre for Interprofessional Simulation, McGill University, Montréal, Que. (Khalil); and the Research Institute of the McGill University Health Centre, McGill University, Montréal, Que. (Harley)., Sun NZ; From McGill University, Montréal, Que. (Grewal, Azher, Moreno, Wiseman, Fried, Lajoie, Sun, Harley); the University of Essex, Colchester, UK (Pekrun); the Ludwig Maximilian University of Munich, Munich, Germany (Pekrun); the Australian Catholic University, Sydney, Australia (Pekrun); the University of Toronto, Toronto, Ont. (Brydges); the University of Victoria, Victoria, B.C. (Hadwin); the McGill University Health Centre for Interprofessional Simulation, McGill University, Montréal, Que. (Khalil); and the Research Institute of the McGill University Health Centre, McGill University, Montréal, Que. (Harley)., Khalil E; From McGill University, Montréal, Que. (Grewal, Azher, Moreno, Wiseman, Fried, Lajoie, Sun, Harley); the University of Essex, Colchester, UK (Pekrun); the Ludwig Maximilian University of Munich, Munich, Germany (Pekrun); the Australian Catholic University, Sydney, Australia (Pekrun); the University of Toronto, Toronto, Ont. (Brydges); the University of Victoria, Victoria, B.C. (Hadwin); the McGill University Health Centre for Interprofessional Simulation, McGill University, Montréal, Que. (Khalil); and the Research Institute of the McGill University Health Centre, McGill University, Montréal, Que. (Harley)., Harley JM; From McGill University, Montréal, Que. (Grewal, Azher, Moreno, Wiseman, Fried, Lajoie, Sun, Harley); the University of Essex, Colchester, UK (Pekrun); the Ludwig Maximilian University of Munich, Munich, Germany (Pekrun); the Australian Catholic University, Sydney, Australia (Pekrun); the University of Toronto, Toronto, Ont. (Brydges); the University of Victoria, Victoria, B.C. (Hadwin); the McGill University Health Centre for Interprofessional Simulation, McGill University, Montréal, Que. (Khalil); and the Research Institute of the McGill University Health Centre, McGill University, Montréal, Que. (Harley)., Nguyen EL; From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (Nguyen); Abdominal Transplant, University Health Network, Toronto, Ont. (Shwaartz); General Surgery, University of Toronto, Toronto, Ont. (Shwaartz, Muaddi); and HPB Surgical Oncology, University Health Network, Toronto, Ont. (Shwaartz, Bucur, Rukavina, Patel)., Patel P; From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (Nguyen); Abdominal Transplant, University Health Network, Toronto, Ont. (Shwaartz); General Surgery, University of Toronto, Toronto, Ont. (Shwaartz, Muaddi); and HPB Surgical Oncology, University Health Network, Toronto, Ont. (Shwaartz, Bucur, Rukavina, Patel)., Muaddi H; From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (Nguyen); Abdominal Transplant, University Health Network, Toronto, Ont. (Shwaartz); General Surgery, University of Toronto, Toronto, Ont. (Shwaartz, Muaddi); and HPB Surgical Oncology, University Health Network, Toronto, Ont. (Shwaartz, Bucur, Rukavina, Patel)., Rukavina N; From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (Nguyen); Abdominal Transplant, University Health Network, Toronto, Ont. (Shwaartz); General Surgery, University of Toronto, Toronto, Ont. (Shwaartz, Muaddi); and HPB Surgical Oncology, University Health Network, Toronto, Ont. (Shwaartz, Bucur, Rukavina, Patel)., Bucur R; From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (Nguyen); Abdominal Transplant, University Health Network, Toronto, Ont. (Shwaartz); General Surgery, University of Toronto, Toronto, Ont. (Shwaartz, Muaddi); and HPB Surgical Oncology, University Health Network, Toronto, Ont. (Shwaartz, Bucur, Rukavina, Patel)., Shwaartz C; From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (Nguyen); Abdominal Transplant, University Health Network, Toronto, Ont. (Shwaartz); General Surgery, University of Toronto, Toronto, Ont. (Shwaartz, Muaddi); and HPB Surgical Oncology, University Health Network, Toronto, Ont. (Shwaartz, Bucur, Rukavina, Patel)., Islam N; From McGill University Health Centre, McGill University, Montréal, Que., Moussa S; From McGill University Health Centre, McGill University, Montréal, Que., Subasri M; From McGill University Health Centre, McGill University, Montréal, Que., Fakih M; From McGill University Health Centre, McGill University, Montréal, Que., Hamdy RC; From McGill University Health Centre, McGill University, Montréal, Que., Wong E; From McGill University Health Centre, McGill University, Montréal, Que., Tewari A; From St. Michael's Hospital, Unity Health Toronto, Toronto, Ont. (Tewari, Brydges, Louridas); and the University of Toronto, Toronto, Ont. (Brydges, Louridas)., Brydges R; From St. Michael's Hospital, Unity Health Toronto, Toronto, Ont. (Tewari, Brydges, Louridas); and the University of Toronto, Toronto, Ont. (Brydges, Louridas)., Louridas M; From St. Michael's Hospital, Unity Health Toronto, Toronto, Ont. (Tewari, Brydges, Louridas); and the University of Toronto, Toronto, Ont. (Brydges, Louridas)., Balaji S; From the University of Toronto, Toronto, Ont. (Balaji, Gaebe, Selzner, Reichman, Shwaartz); the University Health Network, Toronto, Ont. (Patel, Luzzi, Kay, Rukavina, Reichman, Shwaartz); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Patel P; From the University of Toronto, Toronto, Ont. (Balaji, Gaebe, Selzner, Reichman, Shwaartz); the University Health Network, Toronto, Ont. (Patel, Luzzi, Kay, Rukavina, Reichman, Shwaartz); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Muaddi H; From the University of Toronto, Toronto, Ont. (Balaji, Gaebe, Selzner, Reichman, Shwaartz); the University Health Network, Toronto, Ont. (Patel, Luzzi, Kay, Rukavina, Reichman, Shwaartz); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Gaebe K; From the University of Toronto, Toronto, Ont. (Balaji, Gaebe, Selzner, Reichman, Shwaartz); the University Health Network, Toronto, Ont. (Patel, Luzzi, Kay, Rukavina, Reichman, Shwaartz); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Luzzi C; From the University of Toronto, Toronto, Ont. (Balaji, Gaebe, Selzner, Reichman, Shwaartz); the University Health Network, Toronto, Ont. (Patel, Luzzi, Kay, Rukavina, Reichman, Shwaartz); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Kay A; From the University of Toronto, Toronto, Ont. (Balaji, Gaebe, Selzner, Reichman, Shwaartz); the University Health Network, Toronto, Ont. (Patel, Luzzi, Kay, Rukavina, Reichman, Shwaartz); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Rukavina N; From the University of Toronto, Toronto, Ont. (Balaji, Gaebe, Selzner, Reichman, Shwaartz); the University Health Network, Toronto, Ont. (Patel, Luzzi, Kay, Rukavina, Reichman, Shwaartz); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Selzner M; From the University of Toronto, Toronto, Ont. (Balaji, Gaebe, Selzner, Reichman, Shwaartz); the University Health Network, Toronto, Ont. (Patel, Luzzi, Kay, Rukavina, Reichman, Shwaartz); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Reichman T; From the University of Toronto, Toronto, Ont. (Balaji, Gaebe, Selzner, Reichman, Shwaartz); the University Health Network, Toronto, Ont. (Patel, Luzzi, Kay, Rukavina, Reichman, Shwaartz); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Shwaartz C; From the University of Toronto, Toronto, Ont. (Balaji, Gaebe, Selzner, Reichman, Shwaartz); the University Health Network, Toronto, Ont. (Patel, Luzzi, Kay, Rukavina, Reichman, Shwaartz); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Balaji S; From the University of Toronto, Toronto, Ont. (Balaji, Reichman, Jayaraman, Shwaartz); the University Health Network, Toronto, Ont. (Shahabinezhad, Patel, Rukavina, Reichman, Shwaartz); Unity Health Toronto, Toronto, Ont. (Jayaraman); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Muaddi H; From the University of Toronto, Toronto, Ont. (Balaji, Reichman, Jayaraman, Shwaartz); the University Health Network, Toronto, Ont. (Shahabinezhad, Patel, Rukavina, Reichman, Shwaartz); Unity Health Toronto, Toronto, Ont. (Jayaraman); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Shahabinezhad A; From the University of Toronto, Toronto, Ont. (Balaji, Reichman, Jayaraman, Shwaartz); the University Health Network, Toronto, Ont. (Shahabinezhad, Patel, Rukavina, Reichman, Shwaartz); Unity Health Toronto, Toronto, Ont. (Jayaraman); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Patel P; From the University of Toronto, Toronto, Ont. (Balaji, Reichman, Jayaraman, Shwaartz); the University Health Network, Toronto, Ont. (Shahabinezhad, Patel, Rukavina, Reichman, Shwaartz); Unity Health Toronto, Toronto, Ont. (Jayaraman); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Rukavina N; From the University of Toronto, Toronto, Ont. (Balaji, Reichman, Jayaraman, Shwaartz); the University Health Network, Toronto, Ont. (Shahabinezhad, Patel, Rukavina, Reichman, Shwaartz); Unity Health Toronto, Toronto, Ont. (Jayaraman); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Reichman T; From the University of Toronto, Toronto, Ont. (Balaji, Reichman, Jayaraman, Shwaartz); the University Health Network, Toronto, Ont. (Shahabinezhad, Patel, Rukavina, Reichman, Shwaartz); Unity Health Toronto, Toronto, Ont. (Jayaraman); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Jayaraman S; From the University of Toronto, Toronto, Ont. (Balaji, Reichman, Jayaraman, Shwaartz); the University Health Network, Toronto, Ont. (Shahabinezhad, Patel, Rukavina, Reichman, Shwaartz); Unity Health Toronto, Toronto, Ont. (Jayaraman); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Shwaartz C; From the University of Toronto, Toronto, Ont. (Balaji, Reichman, Jayaraman, Shwaartz); the University Health Network, Toronto, Ont. (Shahabinezhad, Patel, Rukavina, Reichman, Shwaartz); Unity Health Toronto, Toronto, Ont. (Jayaraman); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Nashed J; From Queen's University, Kingston, Ont., Ramelli L; From Queen's University, Kingston, Ont., Kolasky O; From Queen's University, Kingston, Ont., Dickenson T; From Queen's University, Kingston, Ont., Dullege M; From Queen's University, Kingston, Ont., Kang A; From Queen's University, Kingston, Ont., Winthrop A; From Queen's University, Kingston, Ont., Mann S; From Queen's University, Kingston, Ont., Lau D; From the University of British Columbia and the B.C. Children's Hospital Research Institute, Vancouver, B.C. (Lau, Henkelman, Watson, Haji); and the B.C. Children's Hospital Digital Laboratory, Vancouver, B.C., (Jacob)., Henkelman E; From the University of British Columbia and the B.C. Children's Hospital Research Institute, Vancouver, B.C. (Lau, Henkelman, Watson, Haji); and the B.C. Children's Hospital Digital Laboratory, Vancouver, B.C., (Jacob)., Jacob J; From the University of British Columbia and the B.C. Children's Hospital Research Institute, Vancouver, B.C. (Lau, Henkelman, Watson, Haji); and the B.C. Children's Hospital Digital Laboratory, Vancouver, B.C., (Jacob)., Watson I; From the University of British Columbia and the B.C. Children's Hospital Research Institute, Vancouver, B.C. (Lau, Henkelman, Watson, Haji); and the B.C. Children's Hospital Digital Laboratory, Vancouver, B.C., (Jacob)., Haji F; From the University of British Columbia and the B.C. Children's Hospital Research Institute, Vancouver, B.C. (Lau, Henkelman, Watson, Haji); and the B.C. Children's Hospital Digital Laboratory, Vancouver, B.C., (Jacob)., McEwen CC; From the Faculty of Health Sciences, McMaster University, Hamilton, Ont. (McEwen, Jaffer, Sibbald); Division of Cardiac Surgery, McMaster University, Hamilton, Ont. (McEwen, Jaffer); Division of Cardiology, McMaster University, Hamilton, Ont. (Sibbald); and the McMaster Education Research, Innovation and Theory Program, McMaster University, Hamilton, Ont. (Sibbald)., Jaffer I; From the Faculty of Health Sciences, McMaster University, Hamilton, Ont. (McEwen, Jaffer, Sibbald); Division of Cardiac Surgery, McMaster University, Hamilton, Ont. (McEwen, Jaffer); Division of Cardiology, McMaster University, Hamilton, Ont. (Sibbald); and the McMaster Education Research, Innovation and Theory Program, McMaster University, Hamilton, Ont. (Sibbald)., Sibbald M; From the Faculty of Health Sciences, McMaster University, Hamilton, Ont. (McEwen, Jaffer, Sibbald); Division of Cardiac Surgery, McMaster University, Hamilton, Ont. (McEwen, Jaffer); Division of Cardiology, McMaster University, Hamilton, Ont. (Sibbald); and the McMaster Education Research, Innovation and Theory Program, McMaster University, Hamilton, Ont. (Sibbald)., Blouin V; From l'Université de Montréal, Montréal, Que. (Blouin, Bénard, Pelletier, Meloche-Dumas, Patocskai); and Ontario Tech University, Oshawa, Ont. (Abdo, Kapralos, Dubrowski)., Bénard F; From l'Université de Montréal, Montréal, Que. (Blouin, Bénard, Pelletier, Meloche-Dumas, Patocskai); and Ontario Tech University, Oshawa, Ont. (Abdo, Kapralos, Dubrowski)., Pelletier F; From l'Université de Montréal, Montréal, Que. (Blouin, Bénard, Pelletier, Meloche-Dumas, Patocskai); and Ontario Tech University, Oshawa, Ont. (Abdo, Kapralos, Dubrowski)., Abdo S; From l'Université de Montréal, Montréal, Que. (Blouin, Bénard, Pelletier, Meloche-Dumas, Patocskai); and Ontario Tech University, Oshawa, Ont. (Abdo, Kapralos, Dubrowski)., Meloche-Dumas L; From l'Université de Montréal, Montréal, Que. (Blouin, Bénard, Pelletier, Meloche-Dumas, Patocskai); and Ontario Tech University, Oshawa, Ont. (Abdo, Kapralos, Dubrowski)., Kapralos B; From l'Université de Montréal, Montréal, Que. (Blouin, Bénard, Pelletier, Meloche-Dumas, Patocskai); and Ontario Tech University, Oshawa, Ont. (Abdo, Kapralos, Dubrowski)., Dubrowski A; From l'Université de Montréal, Montréal, Que. (Blouin, Bénard, Pelletier, Meloche-Dumas, Patocskai); and Ontario Tech University, Oshawa, Ont. (Abdo, Kapralos, Dubrowski)., Patocskai E; From l'Université de Montréal, Montréal, Que. (Blouin, Bénard, Pelletier, Meloche-Dumas, Patocskai); and Ontario Tech University, Oshawa, Ont. (Abdo, Kapralos, Dubrowski)., Pachchigar P; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montréal, Que. (Pachchigar, Agu, Yilmaz, Tee Del Maestro); and l'École polytechnique universitaire de Marseille, Marseille, France (Agu)., Agu C; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montréal, Que. (Pachchigar, Agu, Yilmaz, Tee Del Maestro); and l'École polytechnique universitaire de Marseille, Marseille, France (Agu)., Yilmaz R; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montréal, Que. (Pachchigar, Agu, Yilmaz, Tee Del Maestro); and l'École polytechnique universitaire de Marseille, Marseille, France (Agu)., Tee T; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montréal, Que. (Pachchigar, Agu, Yilmaz, Tee Del Maestro); and l'École polytechnique universitaire de Marseille, Marseille, France (Agu)., Maestro RD; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montréal, Que. (Pachchigar, Agu, Yilmaz, Tee Del Maestro); and l'École polytechnique universitaire de Marseille, Marseille, France (Agu)., Adedipe I; From the Cumming School of Medicine, University of Calgary, Calgary, Alb., Stephens C; From the Cumming School of Medicine, University of Calgary, Calgary, Alb., Ghebretatios M; From the Cumming School of Medicine, University of Calgary, Calgary, Alb., Laplante S; From the University Health Network, Toronto, Ont. (Patel, Laplante, Rukavina, Shwaartz); the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (Balaji); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Patel P; From the University Health Network, Toronto, Ont. (Patel, Laplante, Rukavina, Shwaartz); the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (Balaji); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Balaji S; From the University Health Network, Toronto, Ont. (Patel, Laplante, Rukavina, Shwaartz); the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (Balaji); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Muaddi H; From the University Health Network, Toronto, Ont. (Patel, Laplante, Rukavina, Shwaartz); the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (Balaji); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Rukavina N; From the University Health Network, Toronto, Ont. (Patel, Laplante, Rukavina, Shwaartz); the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (Balaji); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Shwaartz C; From the University Health Network, Toronto, Ont. (Patel, Laplante, Rukavina, Shwaartz); the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (Balaji); and the Mayo Clinic, Rochester, Minn. (Muaddi)., Brodovsky M; From the University of Toronto, Toronto, Ont. (Brodovsky, Behzadi); the Sunnybrook Health Sciences Centre, Toronto, Ont. (Lai); and the University of British Columbia, Vancouver, B.C. (Blair)., Lai C; From the University of Toronto, Toronto, Ont. (Brodovsky, Behzadi); the Sunnybrook Health Sciences Centre, Toronto, Ont. (Lai); and the University of British Columbia, Vancouver, B.C. (Blair)., Behzadi A; From the University of Toronto, Toronto, Ont. (Brodovsky, Behzadi); the Sunnybrook Health Sciences Centre, Toronto, Ont. (Lai); and the University of British Columbia, Vancouver, B.C. (Blair)., Blair G; From the University of Toronto, Toronto, Ont. (Brodovsky, Behzadi); the Sunnybrook Health Sciences Centre, Toronto, Ont. (Lai); and the University of British Columbia, Vancouver, B.C. (Blair)., Almansouri A; From McGill University, Montréal, Que., Hamdan NA; From McGill University, Montréal, Que., Yilmaz R; From McGill University, Montréal, Que., Tee T; From McGill University, Montréal, Que., Pachchigar P; From McGill University, Montréal, Que., Eskandari M; From McGill University, Montréal, Que., Agu C; From McGill University, Montréal, Que., Giglio B; From McGill University, Montréal, Que., Balasubramaniam N; From McGill University, Montréal, Que., Bierbrier J; From McGill University, Montréal, Que., Collins DL; From McGill University, Montréal, Que., Gueziri HE; From McGill University, Montréal, Que., Del Maestro RF; From McGill University, Montréal, Que., Koonar E; From the University of Calgary, Calgary, Alb. (Koonar, Ramazani, Hart, Henley, Roberts, Chandarana, W. Matthews, Schrag, J. Matthews, Mackenzie, Lui); and New York University, New York, NY (Cutting)., Ramazani F; From the University of Calgary, Calgary, Alb. (Koonar, Ramazani, Hart, Henley, Roberts, Chandarana, W. Matthews, Schrag, J. Matthews, Mackenzie, Lui); and New York University, New York, NY (Cutting)., Hart R; From the University of Calgary, Calgary, Alb. (Koonar, Ramazani, Hart, Henley, Roberts, Chandarana, W. Matthews, Schrag, J. Matthews, Mackenzie, Lui); and New York University, New York, NY (Cutting)., Henley J; From the University of Calgary, Calgary, Alb. (Koonar, Ramazani, Hart, Henley, Roberts, Chandarana, W. Matthews, Schrag, J. Matthews, Mackenzie, Lui); and New York University, New York, NY (Cutting)., Roberts S; From the University of Calgary, Calgary, Alb. (Koonar, Ramazani, Hart, Henley, Roberts, Chandarana, W. Matthews, Schrag, J. Matthews, Mackenzie, Lui); and New York University, New York, NY (Cutting)., Chandarana S; From the University of Calgary, Calgary, Alb. (Koonar, Ramazani, Hart, Henley, Roberts, Chandarana, W. Matthews, Schrag, J. Matthews, Mackenzie, Lui); and New York University, New York, NY (Cutting)., Matthews W; From the University of Calgary, Calgary, Alb. (Koonar, Ramazani, Hart, Henley, Roberts, Chandarana, W. Matthews, Schrag, J. Matthews, Mackenzie, Lui); and New York University, New York, NY (Cutting)., Schrag C; From the University of Calgary, Calgary, Alb. (Koonar, Ramazani, Hart, Henley, Roberts, Chandarana, W. Matthews, Schrag, J. Matthews, Mackenzie, Lui); and New York University, New York, NY (Cutting)., Matthews J; From the University of Calgary, Calgary, Alb. (Koonar, Ramazani, Hart, Henley, Roberts, Chandarana, W. Matthews, Schrag, J. Matthews, Mackenzie, Lui); and New York University, New York, NY (Cutting)., Mackenzie D; From the University of Calgary, Calgary, Alb. (Koonar, Ramazani, Hart, Henley, Roberts, Chandarana, W. Matthews, Schrag, J. Matthews, Mackenzie, Lui); and New York University, New York, NY (Cutting)., Cutting C; From the University of Calgary, Calgary, Alb. (Koonar, Ramazani, Hart, Henley, Roberts, Chandarana, W. Matthews, Schrag, J. Matthews, Mackenzie, Lui); and New York University, New York, NY (Cutting)., Lui J; From the University of Calgary, Calgary, Alb. (Koonar, Ramazani, Hart, Henley, Roberts, Chandarana, W. Matthews, Schrag, J. Matthews, Mackenzie, Lui); and New York University, New York, NY (Cutting)., Delisle É; From the Université de Montréal, Montréal, Que. (Delisle, T. Cordoba); and the Centre hospitalier universitaire de Montréal, Montréal, Que. (C. Cordoba)., Cordoba T; From the Université de Montréal, Montréal, Que. (Delisle, T. Cordoba); and the Centre hospitalier universitaire de Montréal, Montréal, Que. (C. Cordoba)., Cordoba C; From the Université de Montréal, Montréal, Que. (Delisle, T. Cordoba); and the Centre hospitalier universitaire de Montréal, Montréal, Que. (C. Cordoba)., Giglio B; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que., Lacroix A; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que., Cairns J; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que., Alsayegh A; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que., Alhantoobi M; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que., Balasubramaniam N; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que., Safih W; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que., Hamel M; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que., Del Maestro R; From the Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University, Montréal, Que., Francis G; From Dalhousie University, Halifax, N.S. (Francis, Hathi); McGill University, Montréal, Que. (Moise); the University of Saskatchewan, Saskatoon, Sask. (Omar); the University of Toronto, Toronto, Ont. (Mavedatnia, Grose); and Queen's University, Kingston, Ont. (Philips)., Moise A; From Dalhousie University, Halifax, N.S. (Francis, Hathi); McGill University, Montréal, Que. (Moise); the University of Saskatchewan, Saskatoon, Sask. (Omar); the University of Toronto, Toronto, Ont. (Mavedatnia, Grose); and Queen's University, Kingston, Ont. (Philips)., Omar Y; From Dalhousie University, Halifax, N.S. (Francis, Hathi); McGill University, Montréal, Que. (Moise); the University of Saskatchewan, Saskatoon, Sask. (Omar); the University of Toronto, Toronto, Ont. (Mavedatnia, Grose); and Queen's University, Kingston, Ont. (Philips)., Hathi K; From Dalhousie University, Halifax, N.S. (Francis, Hathi); McGill University, Montréal, Que. (Moise); the University of Saskatchewan, Saskatoon, Sask. (Omar); the University of Toronto, Toronto, Ont. (Mavedatnia, Grose); and Queen's University, Kingston, Ont. (Philips)., Mavedatnia D; From Dalhousie University, Halifax, N.S. (Francis, Hathi); McGill University, Montréal, Que. (Moise); the University of Saskatchewan, Saskatoon, Sask. (Omar); the University of Toronto, Toronto, Ont. (Mavedatnia, Grose); and Queen's University, Kingston, Ont. (Philips)., Grose E; From Dalhousie University, Halifax, N.S. (Francis, Hathi); McGill University, Montréal, Que. (Moise); the University of Saskatchewan, Saskatoon, Sask. (Omar); the University of Toronto, Toronto, Ont. (Mavedatnia, Grose); and Queen's University, Kingston, Ont. (Philips)., Philips T; From Dalhousie University, Halifax, N.S. (Francis, Hathi); McGill University, Montréal, Que. (Moise); the University of Saskatchewan, Saskatoon, Sask. (Omar); the University of Toronto, Toronto, Ont. (Mavedatnia, Grose); and Queen's University, Kingston, Ont. (Philips)., Schneider C; From the Institut de Cardiologie de Montréal, Montréal, Que.; and the Université de Montréal, Montréal, Que., Corbin D; From the Institut de Cardiologie de Montréal, Montréal, Que.; and the Université de Montréal, Montréal, Que., Lesage F; From the Institut de Cardiologie de Montréal, Montréal, Que.; and the Université de Montréal, Montréal, Que., Pellerin M; From the Institut de Cardiologie de Montréal, Montréal, Que.; and the Université de Montréal, Montréal, Que., Ben-Ali W; From the Institut de Cardiologie de Montréal, Montréal, Que.; and the Université de Montréal, Montréal, Que., Tamani Z; From the Faculty of Medicine, Université de Montréal, Montréal, Que. (Tamani, Joly-Chevrier, Laflamme); General Surgery, Université de Montréal, Montréal, Que. (Bénard, Meloche-Dumas); Surgical Oncology, Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Younan); and Health Sciences, maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski, Patocskai)., Joly-Chevrier M; From the Faculty of Medicine, Université de Montréal, Montréal, Que. (Tamani, Joly-Chevrier, Laflamme); General Surgery, Université de Montréal, Montréal, Que. (Bénard, Meloche-Dumas); Surgical Oncology, Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Younan); and Health Sciences, maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski, Patocskai)., Bénard F; From the Faculty of Medicine, Université de Montréal, Montréal, Que. (Tamani, Joly-Chevrier, Laflamme); General Surgery, Université de Montréal, Montréal, Que. (Bénard, Meloche-Dumas); Surgical Oncology, Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Younan); and Health Sciences, maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski, Patocskai)., Meloche-Dumas L; From the Faculty of Medicine, Université de Montréal, Montréal, Que. (Tamani, Joly-Chevrier, Laflamme); General Surgery, Université de Montréal, Montréal, Que. (Bénard, Meloche-Dumas); Surgical Oncology, Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Younan); and Health Sciences, maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski, Patocskai)., Laflamme L; From the Faculty of Medicine, Université de Montréal, Montréal, Que. (Tamani, Joly-Chevrier, Laflamme); General Surgery, Université de Montréal, Montréal, Que. (Bénard, Meloche-Dumas); Surgical Oncology, Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Younan); and Health Sciences, maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski, Patocskai)., Boulva K; From the Faculty of Medicine, Université de Montréal, Montréal, Que. (Tamani, Joly-Chevrier, Laflamme); General Surgery, Université de Montréal, Montréal, Que. (Bénard, Meloche-Dumas); Surgical Oncology, Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Younan); and Health Sciences, maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski, Patocskai)., Younan R; From the Faculty of Medicine, Université de Montréal, Montréal, Que. (Tamani, Joly-Chevrier, Laflamme); General Surgery, Université de Montréal, Montréal, Que. (Bénard, Meloche-Dumas); Surgical Oncology, Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Younan); and Health Sciences, maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski, Patocskai)., Dubrowski A; From the Faculty of Medicine, Université de Montréal, Montréal, Que. (Tamani, Joly-Chevrier, Laflamme); General Surgery, Université de Montréal, Montréal, Que. (Bénard, Meloche-Dumas); Surgical Oncology, Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Younan); and Health Sciences, maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski, Patocskai)., Patocskai E; From the Faculty of Medicine, Université de Montréal, Montréal, Que. (Tamani, Joly-Chevrier, Laflamme); General Surgery, Université de Montréal, Montréal, Que. (Bénard, Meloche-Dumas); Surgical Oncology, Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Younan); and Health Sciences, maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski, Patocskai)., Sticca G; From the Université de Montréal, Montréal, Que. (Sticca); McGill University, Montréal, Que. (Petruccelli); and the University of Sherbrooke, Sherbrooke, Que. (Dorion)., Petruccelli J; From the Université de Montréal, Montréal, Que. (Sticca); McGill University, Montréal, Que. (Petruccelli); and the University of Sherbrooke, Sherbrooke, Que. (Dorion)., Dorion D; From the Université de Montréal, Montréal, Que. (Sticca); McGill University, Montréal, Que. (Petruccelli); and the University of Sherbrooke, Sherbrooke, Que. (Dorion)., Osman Y; From the Université de Montréal, Montréal, Que. (Osman, Bénard, Habti, Meloche-Dumas); McGill University, Montréal, Que. (Duranleau); the Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Kaviani, Younan, Patocskai); the maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski); and Dawson College, Montréal, Que. (Vessella)., Bénard F; From the Université de Montréal, Montréal, Que. (Osman, Bénard, Habti, Meloche-Dumas); McGill University, Montréal, Que. (Duranleau); the Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Kaviani, Younan, Patocskai); the maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski); and Dawson College, Montréal, Que. (Vessella)., Habti M; From the Université de Montréal, Montréal, Que. (Osman, Bénard, Habti, Meloche-Dumas); McGill University, Montréal, Que. (Duranleau); the Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Kaviani, Younan, Patocskai); the maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski); and Dawson College, Montréal, Que. (Vessella)., Meloche-Dumas L; From the Université de Montréal, Montréal, Que. (Osman, Bénard, Habti, Meloche-Dumas); McGill University, Montréal, Que. (Duranleau); the Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Kaviani, Younan, Patocskai); the maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski); and Dawson College, Montréal, Que. (Vessella)., Duranleau X; From the Université de Montréal, Montréal, Que. (Osman, Bénard, Habti, Meloche-Dumas); McGill University, Montréal, Que. (Duranleau); the Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Kaviani, Younan, Patocskai); the maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski); and Dawson College, Montréal, Que. (Vessella)., Boulva K; From the Université de Montréal, Montréal, Que. (Osman, Bénard, Habti, Meloche-Dumas); McGill University, Montréal, Que. (Duranleau); the Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Kaviani, Younan, Patocskai); the maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski); and Dawson College, Montréal, Que. (Vessella)., Kaviani A; From the Université de Montréal, Montréal, Que. (Osman, Bénard, Habti, Meloche-Dumas); McGill University, Montréal, Que. (Duranleau); the Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Kaviani, Younan, Patocskai); the maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski); and Dawson College, Montréal, Que. (Vessella)., Younan R; From the Université de Montréal, Montréal, Que. (Osman, Bénard, Habti, Meloche-Dumas); McGill University, Montréal, Que. (Duranleau); the Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Kaviani, Younan, Patocskai); the maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski); and Dawson College, Montréal, Que. (Vessella)., Dubrowski A; From the Université de Montréal, Montréal, Que. (Osman, Bénard, Habti, Meloche-Dumas); McGill University, Montréal, Que. (Duranleau); the Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Kaviani, Younan, Patocskai); the maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski); and Dawson College, Montréal, Que. (Vessella)., Vessella K; From the Université de Montréal, Montréal, Que. (Osman, Bénard, Habti, Meloche-Dumas); McGill University, Montréal, Que. (Duranleau); the Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Kaviani, Younan, Patocskai); the maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski); and Dawson College, Montréal, Que. (Vessella)., Patocskai E; From the Université de Montréal, Montréal, Que. (Osman, Bénard, Habti, Meloche-Dumas); McGill University, Montréal, Que. (Duranleau); the Centre hospitalier de l'université de Montréal, Montréal, Que. (Boulva, Kaviani, Younan, Patocskai); the maxSIMhealth Laboratory, Ontario Tech University, Oshawa, Ont. (Dubrowski); and Dawson College, Montréal, Que. (Vessella)., Valji R; From the University of Alberta, Edmonton, Alb., Turner S; From the University of Alberta, Edmonton, Alb., Lam T; From the University of Toronto, Toronto, Ont., Mobilio MH; From the University of Toronto, Toronto, Ont., Hirsh J; From the University of Toronto, Toronto, Ont., Lising D; From the University of Toronto, Toronto, Ont., Cil T; From the University of Toronto, Toronto, Ont., Marcon E; From the University of Toronto, Toronto, Ont., Moulton CA; From the University of Toronto, Toronto, Ont., D'Souza A; From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (D'Souza, Milazzo, Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel); and the Division of Plastic, Reconstructive & Aesthetic Surgery, University of Toronto, Toronto, Ont. (Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel)., Milazzo T; From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (D'Souza, Milazzo, Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel); and the Division of Plastic, Reconstructive & Aesthetic Surgery, University of Toronto, Toronto, Ont. (Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel)., Datta S; From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (D'Souza, Milazzo, Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel); and the Division of Plastic, Reconstructive & Aesthetic Surgery, University of Toronto, Toronto, Ont. (Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel)., Valiquette C; From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (D'Souza, Milazzo, Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel); and the Division of Plastic, Reconstructive & Aesthetic Surgery, University of Toronto, Toronto, Ont. (Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel)., Avery E; From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (D'Souza, Milazzo, Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel); and the Division of Plastic, Reconstructive & Aesthetic Surgery, University of Toronto, Toronto, Ont. (Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel)., Voineskos S; From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (D'Souza, Milazzo, Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel); and the Division of Plastic, Reconstructive & Aesthetic Surgery, University of Toronto, Toronto, Ont. (Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel)., Musgrave M; From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (D'Souza, Milazzo, Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel); and the Division of Plastic, Reconstructive & Aesthetic Surgery, University of Toronto, Toronto, Ont. (Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel)., Wanzel K; From the Temerty Faculty of Medicine, University of Toronto, Toronto, Ont. (D'Souza, Milazzo, Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel); and the Division of Plastic, Reconstructive & Aesthetic Surgery, University of Toronto, Toronto, Ont. (Datta, Valiquette, Avery, Voineskos, Musgrave, Wanzel)., Schneidman J; From McGill University, Montréal, Que. (Schneidman); and the University of Oxford, Oxford, UK (Schneidman, Armstrong)., Armstrong N; From McGill University, Montréal, Que. (Schneidman); and the University of Oxford, Oxford, UK (Schneidman, Armstrong)., Gerardis G; From McGill University, Montréal, Que., Silver J; From McGill University, Montréal, Que., Azzam MA; From McGill University, Montréal, Que., Fisher R; From McGill University, Montréal, Que., Banks I; From McGill University, Montréal, Que., Young M; From McGill University, Montréal, Que., Nguyen LH; From McGill University, Montréal, Que., Skakum M; From the University of Manitoba, Winnipeg, Man., Hancock BJ; From the University of Manitoba, Winnipeg, Man., Min SL; From the University of Manitoba, Winnipeg, Man., Youssef F; From the University of Manitoba, Winnipeg, Man., Keijzer R; From the University of Manitoba, Winnipeg, Man., Morris M; From the University of Manitoba, Winnipeg, Man., Shawyer A; From the University of Manitoba, Winnipeg, Man., Retrosi G; From the University of Manitoba, Winnipeg, Man.

Publikováno v: Canadian journal of surgery. Journal canadien de chirurgie [Can J Surg] 2023 Dec 08; Vol. 66 (6 Suppl 2), pp. S137-S150. Date of Electronic Publication: 2023 Dec 08 (Print Publication: 2023).