Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ghazia Asif"'
Autor:
Patricia L. Hall, Kimiyo Raymond, William A. Gahl, Carlos Ferreira, Lynne A. Wolfe, Hudson H. Freeze, Christina Lam, Gerard T. Berry, Kim K. Nickander, John J. Alexander, Caroline M. Watson, Jon D. Sharer, Ghazia Asif
Publikováno v:
Molecular Genetics and Metabolism. 124:82-86
N-glycanase deficiency (NGLY1 deficiency, NGLY1-CDDG), the first autosomal recessive congenital disorder of N-linked deglycosylation (CDDG), is caused by pathogenic variants in NGLY1. The majority of affected individuals have been identified using ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e029f542c0bd6903e4a326fa9abd7863
https://doi.org/10.1016/j.ymgme.2018.03.002
https://doi.org/10.1016/j.ymgme.2018.03.002
Autor:
Raymond F. Schinazi, Steven J. Coats, Nicolas Sluis-Cremer, Jeffrey D. Meteer, Dianna Koontz, Ghazia Asif, Mervi Detorio, John W. Mellors, Sarah Solomon, Hongwang Zhang
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:3758-3764
We recently reported that HIV-1 resistant to 3′-azido-3′-deoxythymidine (AZT) is not cross-resistant to 3′-azido-2′,3′-dideoxypurines. This finding suggested that the nucleoside base is a major determinant of HIV-1 resistance to nucleoside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fd6d0a1337634616c1ce8c7fd75f04
https://doi.org/10.1128/aac.00414-11
https://doi.org/10.1128/aac.00414-11
Publikováno v:
Antimicrobial Agents and Chemotherapy. 54:1248-1255
Amdoxovir (AMDX) inhibits HIV-1 containing the M184V/I mutation and is rapidly absorbed and deaminated to its active metabolite, β-d-dioxolane guanosine (DXG). DXG is synergistic with zidovudine (ZDV) in HIV-1-infected primary human lymphocytes. A r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fe59b681fbb501413dbe92937c9864
https://doi.org/10.1128/aac.01209-09
https://doi.org/10.1128/aac.01209-09
Publikováno v:
Journal of Chromatography B. 877:3482-3488
A sensitive method was developed and validated for simultaneous measurement of an investigational antiviral nucleoside, Amdoxovir (DAPD), its deaminated metabolite 9-(β- d -1,3-dioxolan-4-yl)guanine (DXG), and Zidovudine (ZDV) in human plasma. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3f5aa11c9d759de99d27736928074b
https://doi.org/10.1016/j.jchromb.2009.08.030
https://doi.org/10.1016/j.jchromb.2009.08.030
Autor:
Brenda I. Hernandez-Santiago, Junxing Shi, Ghazia Asif, Raymond F. Schinazi, Selwyn J. Hurwitz
Publikováno v:
Antimicrobial Agents and Chemotherapy. 51:2877-2882
β- d -2′-Deoxy-2′-fluoro-2′- C -methylcytidine (PSI-6130) is an effective inhibitor of hepatitis C virus (HCV) replication in vitro. The purpose of this study was to evaluate the single-dose pharmacokinetics of PSΙ-6130 in rhesus monkeys foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cedd15faf7464187091af0edb3658a
https://doi.org/10.1128/aac.00193-07
https://doi.org/10.1128/aac.00193-07
Autor:
Raymond F. Schinazi, Aleksandr Obikhod, Selwyn J. Hurwitz, Janarthanan Narayanasamy, Ghazia Asif, Harold M. McClure, David Delinsky, Chung K. Chu
Publikováno v:
Antimicrobial Agents and Chemotherapy. 51:2424-2429
β-d-Dioxolane-thymine (D-DOT) has potent and selective in vitro activity against several clinically important resistant human immunodeficiency virus (HIV) mutants and is in advanced preclinical development. Therefore, the single-dose intravenous and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a14cebc4472e01bb8a0fe724fe35fb46
https://doi.org/10.1128/aac.01498-06
https://doi.org/10.1128/aac.01498-06
Autor:
Hudson H. Freeze, Miao He, Madhuri Hegde, Tongzhong Ju, Katie Clarkson, Bobby G. Ng, Philip James, Kimiyo Raymond, Ghazia Asif, Xueli Li, Jiang Rong, Tim Wood, Baoyun Xia, Richard D. Cummings, Cornelius F. Boerkoel, Wenyue Zhang, Melanie A. Jones
Publikováno v:
Clinical chemistry. 62(1)
BACKGROUND Primary deficiencies in mannosylation of N-glycans are seen in a majority of patients with congenital disorders of glycosylation (CDG). We report the discovery of a series of novel N-glycans in sera, plasma, and cultured skin fibroblasts f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d14082aa0b8d6acdc8287cf119a72b7
https://pubmed.ncbi.nlm.nih.gov/26585926
https://pubmed.ncbi.nlm.nih.gov/26585926
Autor:
Sushma R. Gundala, N. Lakshminarayana, Ghazia Asif, Chunhua Yang, Meenakshi V. Gupta, Shahab A. Shamsi, Ritu Aneja
Publikováno v:
Carcinogenesis. 34(9)
Polyphenolic phytochemicals present in fruits and vegetables indisputably confer anticancer benefits upon regular consumption. Recently, we demonstrated the growth-inhibitory and apoptosis-inducing properties of polyphenol-rich sweet potato greens ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b32d84bfdc88e44eade7015d75a93f3
https://pubmed.ncbi.nlm.nih.gov/23629419
https://pubmed.ncbi.nlm.nih.gov/23629419
Publikováno v:
Nutrition and cancer. 65(2)
Dietary phytochemicals offer non-toxic therapeutic management as well as chemopreventive intervention for slow-growing prostate cancers. However, the limited success of several single-agent clinical trials suggest a paradigm shift that the health ben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4086986f4851a34f7101aab3802f15b3
https://pubmed.ncbi.nlm.nih.gov/23441614
https://pubmed.ncbi.nlm.nih.gov/23441614
Autor:
Meenakshi V. Gupta, Sushma R. Gundala, Ritu Aneja, Sharmeen Chagani, Prasanthi Karna, Vibhuti Sharma, Padmashree C.G. Rida, Ghazia Asif
It is appreciated far and wide that increased and regular consumption of fruits and vegetables is linked with noteworthy anticancer benefits. Extensively consumed as a spice in foods and beverages worldwide, ginger (Zingiber officinale Roscoe) is an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00be38bf3e39a8c683736edb2784c0b4
https://europepmc.org/articles/PMC3426621/
https://europepmc.org/articles/PMC3426621/
