Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ghazaleh Ashrafi"'
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114218- (2024)
Summary: Glucose has long been considered a primary energy source for synaptic function. However, it remains unclear to what extent alternative fuels, such as lactate/pyruvate, contribute to powering synaptic transmission. By detecting individual rel
Externí odkaz:
https://doaj.org/article/53c71f985bfd4f40b24c6ff2dc765e1d
Autor:
Anupama Tiwari, Arsalan Hashemiaghdam, Marissa A. Laramie, Dario Maschi, Tristaan Haddad, Marion I. Stunault, Carmen Bergom, Ali Javaheri, Vitaly Klyachko, Ghazaleh Ashrafi
Publikováno v:
bioRxiv
Neurotransmission is an energetically expensive process that underlies cognition. During intense electrical activity or dietary restrictions, glucose levels in the brain plummet, forcing neurons to utilize alternative fuels. However, the molecular me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5646998a6a3c7f8e63d041cf8cd8b138
https://doi.org/10.1101/2023.03.08.531724
https://doi.org/10.1101/2023.03.08.531724
Autor:
Marion I. Stunault, Ghazaleh Ashrafi
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::270cd8c4ccf2b78c2a9785866f454555
https://doi.org/10.1016/b978-0-12-821618-7.00215-7
https://doi.org/10.1016/b978-0-12-821618-7.00215-7
Publikováno v:
Neurophotonics. 9
Autor:
Angelika B. Harbauer, J. Tabitha Hees, Simone Wanderoy, Inmaculada Segura, Whitney Gibbs, Yiming Cheng, Martha Ordonez, Zerong Cai, Romain Cartoni, Ghazaleh Ashrafi, Chen Wang, Fabiana Perocchi, Zhigang He, Thomas L. Schwarz
Publikováno v:
Neuron 110, 1516-1531.e9 (2022)
PTEN-induced kinase 1 (PINK1) is a short-lived protein required for the removal of damaged mitochondria through Parkin translocation and mitophagy. Because the short half-life of PINK1 limits its ability to be trafficked into neurites, local translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa706e9325823230f048bfb2512a6aa
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64542
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64542
SignificanceThe firefly enzyme luciferase has been used in a wide range of biological assays, including bioluminescence imaging of ATP. The biosensor Syn-ATP utilizes subcellular targeting of luciferase to nerve terminals for optical measurement of A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbc895093edc72a0e7d48fc08bb3af18
https://doi.org/10.1101/2021.09.20.461141
https://doi.org/10.1101/2021.09.20.461141
Biowaste- and nature-derived (nano)materials: Biosynthesis, stability and environmental applications
Publikováno v:
Advances in colloid and interface science. 301
Due to the environmental pollution issues and the supply of drinking/clean water, removal of both inorganic and organic (particularly dyes, nitroarenes, and heavy metals) to non-dangerous products and useful compounds are very important transformatio
Publikováno v:
Advanced Biology
Mitochondria are the main suppliers of neuronal adenosine triphosphate and play a critical role in brain energy metabolism. Mitochondria also serve as Ca2+ sinks and anabolic factories and are therefore essential for neuronal function and survival. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd737508dac3939c8b9e169485fa0e96
https://hdl.handle.net/21.11116/0000-0009-9A31-221.11116/0000-0009-9A33-0
https://hdl.handle.net/21.11116/0000-0009-9A31-221.11116/0000-0009-9A33-0
Autor:
Ghazaleh Ashrafi, Timothy A. Ryan
Publikováno v:
Current Opinion in Neurobiology. 45:156-161
Nerve terminals in the brain carry out the primary form of intercellular communication between neurons. Neurotransmission, however, requires adequate supply of ATP to support energetically demanding steps, including the maintenance of ionic gradients
Autor:
Alexandros K. Kanellopoulos, Neale Bm, Harold D. MacGillavry, Mahdokht Kohansal-Nodehi, Natasha K. Hussain, Rebecca E. Foulger, Vincent O'Connor, Ruud F. Toonen, Ghazaleh Ashrafi, Camila Pulido, Cordelia Imig, Arthur P.H. de Jong, Michael R. Kreutz, L. Niels Cornelisse, Timothy A. Ryan, Tilmann Achsel, Guoping Feng, Morgan Sheng, John Jia En Chua, Eckart D. Gundelfinger, Paul Thomas, David Osumi-Sutherland, Noa Lipstein, Haiming Tang, Danielle Posthuma, Hagen Tilgner, Chiara Verpelli, Nimra Asi, Kyoko Watanabe, Pietro De Camilli, Hana L. Goldschmidt, Jaime de Juan-Sanz, Rita Reig-Viader, Momchil Ninov, Barbara Kramarz, Àlex Bayés, Peter S. McPherson, Pim van Nierop, Hwajin Jung, Tony Cijsouw, Huaiyu Mi, Pascal S. Kaeser, Thomas C. Südhof, Marcelo P. Coba, Eunjoon Kim, Richard L. Huganir, Robert C. Malenka, Marc Feuermann, Daniel P. Howrigan, Roger A. Nicoll, Nils Brose, Pascale Gaudet, Daniela C. Dieterich, Andrea Byrnes, Carlo Sala, Anoushka Joglekar, Jan R.T. van Weering, Claudia Bagni, Frank Koopmans, Casper C. Hoogenraad, Matthijs Verhage, Katherine Tashman, Ryan J. Farrell, Vittoria Mariano, Rainer Pielot, Thomas Biederer, Reinhard Jahn, August B. Smit, Ruth C. Lovering, Karl-Heinz Smalla, Maria Andres-Alonso, Steven E. Hyman, Tyler C. Brown
Publikováno v:
Neuron, 103(2), 217. Cell Press
Neuron
Koopmans, F, van Nierop, P, Andres-Alonso, M, Byrnes, A, Cijsouw, T, Coba, M P, Cornelisse, L N, Farrell, R J, Goldschmidt, H L, Howrigan, D P, Hussain, N K, Imig, C, de Jong, A P H, Jung, H, Kohansalnodehi, M, Kramarz, B, Lipstein, N, Lovering, R C, MacGillavry, H, Mariano, V, Mi, H, Ninov, M, Osumi-Sutherland, D, Pielot, R, Smalla, K-H, Tang, H, Tashman, K, Toonen, R F G, Verpelli, C, Reig-Viader, R, Watanabe, K, van Weering, J, Achsel, T, Ashrafi, G, Asi, N, Brown, T C, de Camilli, P, Feuermann, M, Foulger, R E, Gaudet, P, Joglekar, A, Kanellopoulos, A, Malenka, R, Nicoll, R A, Pulido, C, de Juan-Sanz, J, Sheng, M, Südhof, T C, Tilgner, H U, Bagni, C, Bayés, À, Biederer, T, Brose, N, Chua, J J E, Dieterich, D C, Gundelfinger, E D, Hoogenraad, C, Huganir, R L, Jahn, R, Kaeser, P S, Kim, E, Kreutz, M R, McPherson, P S, Neale, B M, O'Connor, V, Posthuma, D, Ryan, T A, Sala, C, Feng, G, Hyman, S E, Thomas, P D, Smit, A B & Verhage, M 2019, ' SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse ', Neuron, vol. 103, no. 2, pp. 217-234.e4 . https://doi.org/10.1016/j.neuron.2019.05.002
Koopmans, F, van Nierop, P, Andres-Alonso, M, Byrnes, A, Cijsouw, T, Coba, M P, Cornelisse, L N, Farrell, R J, Goldschmidt, H L, Howrigan, D P, Hussain, N K, Imig, C, de Jong, A P H, Jung, H, Kohansalnodehi, M, Kramarz, B, Lipstein, N, Lovering, R C, MacGillavry, H, Mariano, V, Mi, H, Ninov, M, Osumi-Sutherland, D, Pielot, R, Smalla, K H, Tang, H, Tashman, K, Toonen, R F G, Verpelli, C, Reig-Viader, R, Watanabe, K, van Weering, J, Achsel, T, Ashrafi, G, Asi, N, Brown, T C, De Camilli, P, Feuermann, M, Foulger, R E, Gaudet, P, Joglekar, A, Kanellopoulos, A, Malenka, R, Nicoll, R A, Pulido, C, de Juan-Sanz, J, Sheng, M, Südhof, T C, Tilgner, H U, Bagni, C, Bayés, À, Biederer, T, Brose, N, Chua, J J E, Dieterich, D C, Gundelfinger, E D, Hoogenraad, C, Huganir, R L, Jahn, R, Kaeser, P S, Kim, E, Kreutz, M R, McPherson, P S, Neale, B M, O'Connor, V, Posthuma, D, Ryan, T A, Sala, C, Feng, G, Hyman, S E, Thomas, P D, Smit, A B & Verhage, M 2019, ' SynGO : An Evidence-Based, Expert-Curated Knowledge Base for the Synapse ', Neuron, vol. 103, no. 2, pp. 217-234.e4 . https://doi.org/10.1016/j.neuron.2019.05.002
NEURON
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
PMC
Neuron, 103(2), 217-234.e4. Cell Press
Neuron
Koopmans, F, van Nierop, P, Andres-Alonso, M, Byrnes, A, Cijsouw, T, Coba, M P, Cornelisse, L N, Farrell, R J, Goldschmidt, H L, Howrigan, D P, Hussain, N K, Imig, C, de Jong, A P H, Jung, H, Kohansalnodehi, M, Kramarz, B, Lipstein, N, Lovering, R C, MacGillavry, H, Mariano, V, Mi, H, Ninov, M, Osumi-Sutherland, D, Pielot, R, Smalla, K-H, Tang, H, Tashman, K, Toonen, R F G, Verpelli, C, Reig-Viader, R, Watanabe, K, van Weering, J, Achsel, T, Ashrafi, G, Asi, N, Brown, T C, de Camilli, P, Feuermann, M, Foulger, R E, Gaudet, P, Joglekar, A, Kanellopoulos, A, Malenka, R, Nicoll, R A, Pulido, C, de Juan-Sanz, J, Sheng, M, Südhof, T C, Tilgner, H U, Bagni, C, Bayés, À, Biederer, T, Brose, N, Chua, J J E, Dieterich, D C, Gundelfinger, E D, Hoogenraad, C, Huganir, R L, Jahn, R, Kaeser, P S, Kim, E, Kreutz, M R, McPherson, P S, Neale, B M, O'Connor, V, Posthuma, D, Ryan, T A, Sala, C, Feng, G, Hyman, S E, Thomas, P D, Smit, A B & Verhage, M 2019, ' SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse ', Neuron, vol. 103, no. 2, pp. 217-234.e4 . https://doi.org/10.1016/j.neuron.2019.05.002
Koopmans, F, van Nierop, P, Andres-Alonso, M, Byrnes, A, Cijsouw, T, Coba, M P, Cornelisse, L N, Farrell, R J, Goldschmidt, H L, Howrigan, D P, Hussain, N K, Imig, C, de Jong, A P H, Jung, H, Kohansalnodehi, M, Kramarz, B, Lipstein, N, Lovering, R C, MacGillavry, H, Mariano, V, Mi, H, Ninov, M, Osumi-Sutherland, D, Pielot, R, Smalla, K H, Tang, H, Tashman, K, Toonen, R F G, Verpelli, C, Reig-Viader, R, Watanabe, K, van Weering, J, Achsel, T, Ashrafi, G, Asi, N, Brown, T C, De Camilli, P, Feuermann, M, Foulger, R E, Gaudet, P, Joglekar, A, Kanellopoulos, A, Malenka, R, Nicoll, R A, Pulido, C, de Juan-Sanz, J, Sheng, M, Südhof, T C, Tilgner, H U, Bagni, C, Bayés, À, Biederer, T, Brose, N, Chua, J J E, Dieterich, D C, Gundelfinger, E D, Hoogenraad, C, Huganir, R L, Jahn, R, Kaeser, P S, Kim, E, Kreutz, M R, McPherson, P S, Neale, B M, O'Connor, V, Posthuma, D, Ryan, T A, Sala, C, Feng, G, Hyman, S E, Thomas, P D, Smit, A B & Verhage, M 2019, ' SynGO : An Evidence-Based, Expert-Curated Knowledge Base for the Synapse ', Neuron, vol. 103, no. 2, pp. 217-234.e4 . https://doi.org/10.1016/j.neuron.2019.05.002
NEURON
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
PMC
Neuron, 103(2), 217-234.e4. Cell Press
© 2019 Elsevier Inc. Synapses are fundamental information-processing units of the brain, and synaptic dysregulation is central to many brain disorders (“synaptopathies”). However, systematic annotation of synaptic genes and ontology of synaptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9363c39520e59a7e5697474577ba275
https://dspace.library.uu.nl/handle/1874/384389
https://dspace.library.uu.nl/handle/1874/384389