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Akademický článek

Deletion of pyruvate dehydrogenase kinases reduces susceptibility to deep vein thrombosis in mice.

Autor: Flora GD; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa, Iowa City, IA., Ghatge M; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa, Iowa City, IA., Nayak MK; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa, Iowa City, IA., Barbhuyan T; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa, Iowa City, IA., Kumskova M; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa, Iowa City, IA., Chauhan AK; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa, Iowa City, IA.

Publikováno v: Blood advances [Blood Adv] 2024 Aug 13; Vol. 8 (15), pp. 3906-3913.

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Akademický článek

Platelet Metabolic Profiling Reveals Glycolytic and 1-Carbon Metabolites Are Essential for GP VI-Stimulated Human Platelets-Brief Report.

Autor: Ghatge M; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa., Flora GD; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa., Nayak MK; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa., Chauhan AK; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa.

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2024 Feb; Vol. 44 (2), pp. 409-416. Date of Electronic Publication: 2023 Nov 09.

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Akademický článek

Metabolic targeting of platelets to combat thrombosis: dawn of a new paradigm?

Autor: Flora GD; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, IA, USA., Nayak MK; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, IA, USA., Ghatge M; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, IA, USA., Chauhan AK; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, IA, USA.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2023 Nov 25; Vol. 119 (15), pp. 2497-2507.

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Akademický článek

Targeting Neutrophil α9 Improves Functional Outcomes After Stroke in Mice With Obesity-Induced Hyperglycemia.

Autor: Patel RB; Division of Hematology/Oncology, Department of Internal Medicine (R.B.P., N.D., B.S., M.G., P.D., T.B., M.K., A.K.C.), University of Iowa, Iowa City., Dhanesha N; Division of Hematology/Oncology, Department of Internal Medicine (R.B.P., N.D., B.S., M.G., P.D., T.B., M.K., A.K.C.), University of Iowa, Iowa City., Sutariya B; Division of Hematology/Oncology, Department of Internal Medicine (R.B.P., N.D., B.S., M.G., P.D., T.B., M.K., A.K.C.), University of Iowa, Iowa City., Ghatge M; Division of Hematology/Oncology, Department of Internal Medicine (R.B.P., N.D., B.S., M.G., P.D., T.B., M.K., A.K.C.), University of Iowa, Iowa City., Doddapattar P; Division of Hematology/Oncology, Department of Internal Medicine (R.B.P., N.D., B.S., M.G., P.D., T.B., M.K., A.K.C.), University of Iowa, Iowa City., Barbhuyan T; Division of Hematology/Oncology, Department of Internal Medicine (R.B.P., N.D., B.S., M.G., P.D., T.B., M.K., A.K.C.), University of Iowa, Iowa City., Kumskova M; Division of Hematology/Oncology, Department of Internal Medicine (R.B.P., N.D., B.S., M.G., P.D., T.B., M.K., A.K.C.), University of Iowa, Iowa City., Leira EC; Departments of Neurology, Neurosurgery and Epidemiology (E.C.L.), University of Iowa, Iowa City., Chauhan AK; Division of Hematology/Oncology, Department of Internal Medicine (R.B.P., N.D., B.S., M.G., P.D., T.B., M.K., A.K.C.), University of Iowa, Iowa City.

Publikováno v: Stroke [Stroke] 2023 Sep; Vol. 54 (9), pp. 2409-2419. Date of Electronic Publication: 2023 Jul 14.

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Akademický článek

Mitochondrial calcium uniporter b deletion inhibits platelet function and reduces susceptibility to arterial thrombosis.

Autor: Ghatge M; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, Iowa, USA. Electronic address: madankumar-ghatge@uiowa.edu., Nayak MK; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, Iowa, USA., Flora GD; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, Iowa, USA., Kumskova M; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, Iowa, USA., Jain A; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, Iowa, USA., Patel RB; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, Iowa, USA., Lin Z; Department of Neuroscience and Pharmacology, University of Iowa, Iowa City, Iowa, USA., Usachev YM; Department of Neuroscience and Pharmacology, University of Iowa, Iowa City, Iowa, USA., Chauhan AK; Department of Internal Medicine, Division of Hematology/Oncology, University of Iowa, Iowa City, Iowa, USA. Electronic address: anil-chauhan@uiowa.edu.

Publikováno v: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2023 Aug; Vol. 21 (8), pp. 2163-2174. Date of Electronic Publication: 2023 Apr 13.

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Akademický článek

Mitochondrial pyruvate dehydrogenase kinases contribute to platelet function and thrombosis in mice by regulating aerobic glycolysis.

Autor: Flora GD; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa, Iowa City, IA., Nayak MK; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa, Iowa City, IA., Ghatge M; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa, Iowa City, IA., Kumskova M; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa, Iowa City, IA., Patel RB; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa, Iowa City, IA., Chauhan AK; Division of Hematology/Oncology, Department of Internal Medicine, University of Iowa, Iowa City, IA.

Publikováno v: Blood advances [Blood Adv] 2023 Jun 13; Vol. 7 (11), pp. 2347-2359.

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