Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows

Autor: Turki M. Sobahy, Ghassan Tashkandi, Donya Bahussain, Raneem Al-Harbi

Publikováno v: BMC Medical Genomics, Vol 15, Iss 1, Pp 1-11 (2022)

Abstract Background The recent development and enormous application of parallel sequencing technology in oncology has produced immense amounts of cell-specific genetic information. However, publicly available cell-specific genetic variants are not ex

Externí odkaz: https://doaj.org/article/56f79749eb9b42589da4858a9ea562c0

Kinetic modelling of in vitro data of PI3K, mTOR1, PTEN enzymes and on-target inhibitors Rapamycin, BEZ235, and LY294002

Autor: Simon P. Langdon, James L. Bown, David J. Harrison, Ghassan Tashkandi, Alexey Goltsov

Publikováno v: Goltsov, A, Tashkandi, G, Langdon, S P, Harrison, D J & Bown, J L 2017, ' Kinetic modelling of in vitro data of PI3K, mTOR1, PTEN enzymes and on-target inhibitors Rapamycin, BEZ235, and LY294002 ', European Journal of Pharmaceutical Sciences, vol. 97 . https://doi.org/10.1016/j.ejps.2016.11.008

This work was supported by grants from the Northwood Trust (AG, JB), personal support to AG from Scottish Informatics and Computer Science Alliance (SICSA), and EU support for the Concerted Action CASyM (DJH). The phosphatidylinositide 3-kinases (PI3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7617f74ad4af4451569b0d52ae913c6
https://hdl.handle.net/10023/12033