Zobrazeno 1 - 10
of 237
pro vyhledávání: '"Ghassan M. Saed"'
Publikováno v:
Reproductive Sciences. 30:291-300
Publikováno v:
Minerva Obstetrics and Gynecology. 75
OBJECTIVE To explore the organic features of redundant endometrium (RE), we examined the expression of different endometrial hormone receptors, oncogenes, and cell replication markers, in normal endometrium (NE), endometrial polyps (EP) and RE specim
Autor:
Farnoosh Qadri, Michael P. Diamond, Awoniyi O. Awonuga, Anupama Rambhatla, Modupe Awonuga, Charalampos Chatzicharalampous, Ghassan M. Saed, Mili Thakur
Publikováno v:
Reproductive Sciences. 29:3055-3077
Intraperitoneal adhesions complicate over half of abdominal-pelvic surgeries with immediate, short, and long-term sequelae of major healthcare concern. The pathogenesis of adhesion development is similar to the pathogenesis of wound healing in all ti
Autor:
Hala LUTFI, Thea K. KIRSCH-MANGU, Nicole M. FLETCHER-KING, Douglas M. RUDEN, Michael P. DIAMOND, Ghassan M. SAED
Publikováno v:
Minerva obstetrics and gynecology.
The link between post-operative adhesion development and epigenetic modifications is important in understanding the mechanism behind their formation. The purpose of this study was to determine whether epigenetic differences exist between primary fibr
Publikováno v:
Minerva Obstetrics and Gynecology.
2,4-dinitrophenol (DNP), an uncoupling mitochondrial agent, has been identified as a source of oxidative stress and linked to the pathogenesis of ovarian cancer. In this study, we determine the cytotoxic effect of DNP alone or in combination with che
Autor:
Faten Shaeib, Sana N Khan, Mili Thakur, Hamid-Reza Kohan-Ghadr, Sascha Drewlo, Ghassan M Saed, Subramaniam Pennathur, Husam M Abu-Soud
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151160 (2016)
Myeloperoxidase (MPO), an abundant heme-containing enzyme present in neutrophils, monocytes, and macrophages, is produced in high levels during inflammation, and associated with poor reproductive outcomes. MPO is known to generate hypochlorous acid (
Externí odkaz:
https://doaj.org/article/e65ed48692764f0eb060f45fe889aee6
Autor:
Awoniyi O. Awonuga, Ghassan M. Saed, Farnoosh Qadri, Modupe Awonuga, Anupama Rambhatla, Mili Thakur, Michael P. Diamond, Charalampos Chatzicharalampous
Publikováno v:
Reproductive Sciences
Adhesions are permanent fibrovascular bands between peritoneal surfaces, which develop following virtually all body cavity surgeries. The susceptibility to develop, and the severity, of adhesions following intra-abdominal surgery varies within and be
Publikováno v:
Gynecological Endocrinology. 37:349-352
To test whether recombinant anti-Müllerian hormone (rAMH) could exert an inhibitory function on BRCA1/2 expression in human ovarian cortex.Pilot study on ovariectomized nude mice xenotransplanted with human vitrified/warmed ovarian cortex and treate
Publikováno v:
Reproductive Sciences. 26:1603-1612
Genital use of talcum powder and its associated risk of ovarian cancer is an important controversial topic. Epithelial ovarian cancer (EOC) cells are known to manifest a persistent prooxidant state. Here we demonstrated that talc induces significant
Autor:
Rong Fan, Ghassan M. Saed, Amy K Harper, Xin Wang, Robert T. Morris, Thea K Mangu, Nicole M. Fletcher
Publikováno v:
Minerva obstetrics and gynecology.
BACKGROUND Several studies have linked perineal use of talcum powder to increased risk of ovarian cancer (OC). Here, we determined that exposure to talcum powder induces malignant transformation in human normal ovarian cells. METHODS Human primary ov