Design and Synthesis of 4-O-Podophyllotoxin Sulfamate Derivatives as Potential Cytotoxic Agents

Autor: Hamed I. Ali, Dima A. Sabbah, Majdi M. Bkhaitan, Ghadeer Albadawi, Ghassan M Abushaikha, Ammar Bader, Qasem M. A. Abdallah, Ashraf N. Abdalla

Publikováno v: Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)

4-O-Podophyllotoxin sulfamate derivatives were prepared using the natural lignan podophyllotoxin. The prepared compounds were afforded by reacting O-sulfonyl chloride podophyllotoxin with ammonia or aminoaryl/heteroaryl motif. Biological evaluation w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef9955d99ed4b21598810cc90af9295
https://pubmed.ncbi.nlm.nih.gov/33574882