Zobrazeno 1 - 10
of 503
pro vyhledávání: '"Ghassan K Abou-Alfa"'
Autor:
Amaia Lujambio, Thomas Yau, Lipika Goyal, Andrew X Zhu, Ignacio Melero, Tim F Greten, Ann-Lii Cheng, Bruno Sangro, David J Pinato, Peter R Galle, Ghassan K Abou-Alfa, Austin G Duffy, Anthony B. El-Khoueiry, Richard S Finn, Aiwu Ruth He, Ahmed O Kaseb, Robin Kate Kelley, Riccardo Lencioni, Donna Mabry Hrones, Roberto I Troisi, Andrea Wilson Woods
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Patients with advanced hepatocellular carcinoma (HCC) have historically had few options and faced extremely poor prognoses if their disease progressed after standard-of-care tyrosine kinase inhibitors (TKIs). Recently, the standard of care for HCC ha
Externí odkaz:
https://doaj.org/article/c395a80c692945e793e9d243958829ae
Autor:
Sara Velayati, Ahmed Elsakka, Ken Zhao, Joseph P. Erinjeri, Brett Marinelli, Mohamed Soliman, Olivier Chevallier, Etay Ziv, Lynn A. Brody, Constantinos T. Sofocleous, Stephen B. Solomon, James J. Harding, Ghassan K. Abou-Alfa, Michael I. D’Angelica, Alice C. Wei, Peter T. Kingham, William R. Jarnagin, Hooman Yarmohammadi
Publikováno v:
Current Oncology, Vol 30, Iss 10, Pp 9181-9191 (2023)
The safety and efficacy of hepatic artery embolization (HAE) in treating intrahepatic cholangiocarcinoma (IHC) was evaluated. Initial treatment response, local tumor progression-free survival (L-PFS), and overall survival (OS) were evaluated in 34 IH
Externí odkaz:
https://doaj.org/article/7cbeab7a43d54e31aadc95f47c6af60a
Publikováno v:
Cancer Medicine, Vol 12, Iss 13, Pp 13978-13990 (2023)
Abstract Hepatocellular carcinoma (HCC) is a major cause of death among patients with liver cirrhosis. The rise of immuno‐oncology has revolutionized treatment for advanced HCC. However, most pivotal randomized controlled trials have excluded patie
Externí odkaz:
https://doaj.org/article/747696b1fb5b4f988dbf26409b98fa8a
Autor:
Fernanda Capareli, Frederico Costa, Jack A. Tuszynski, Micelange C. Sousa, Yone de C. Setogute, Pablo D. Lima, Luciana Carvalho, Elizabeth Santos, Brenda P. Gumz, Jorge Sabbaga, Tiago B. deCastria, Denis L. Jardim, Daniela Freitas, Natally Horvat, Regis O. F. Bezerra, Leonardo Testagrossa, Tiago Costa, Tatiana Zanesco, Antonio F. Iemma, Ghassan K. Abou‐Alfa
Publikováno v:
Cancer Medicine, Vol 12, Iss 11, Pp 12402-12412 (2023)
Abstract Background Patients with advanced hepatocellular carcinoma (HCC) and poor liver function lack effective systemic therapies. Low‐energy electromagnetic fields (EMFs) can influence cell biological processes via non‐thermal effects and may
Externí odkaz:
https://doaj.org/article/e607313da1734bf38413f03a8853d977
Autor:
Travis Zack, Kurt P. Losert, Samantha M. Maisel, Jennifer Wild, Amin Yaqubie, Michael Herman, Jennifer J. Knox, Robert J. Mayer, Alan P. Venook, Atul Butte, Allison F. O’Neill, Ghassan K. Abou-Alfa, John D. Gordan
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-6 (2023)
Abstract The incidence and biochemical consequences of rare tumor subtypes are often hard to study. Fibrolamellar liver cancer (FLC) is a rare malignancy affecting adolescents and young adults. To better characterize the incidence and biochemical con
Externí odkaz:
https://doaj.org/article/a6be12a913714c2aaed7398302e34be1
Autor:
Ghassan K. Abou-Alfa, Mary Afihene, Marinela Capanu, Yuelin Li, Joanne F. Chou, Akwi Asombang, Olusegun Isaac Alatise, Adda Bounedjar, Lina Cunha, Hailemichael Desalegn Mekonnen, Papa Saloum Diop, Reda Elwakil, Mahamat Moussa Ali, Ntokozo Ndlovu, Jerry Ndumbalo, Precious Takondwa Makondi, Christian Tzeuton, Tiago Biachi de Castria, Adwoa Afrakoma Agyei-Nkansah, Fiyinfolu Balogun, Alain Bougouma, Blaise Irénée Atipo Ibara, Eduard Jonas, Stephen Kimani, Peter Kingham, Reshad Kurrimbukus, Nazik Hammad, Mona Fouad, Noha El Baghdady, Eloumou Bagnaka Servais Albert Fiacre, Vikash Sewram, C. Wendy Spearman, Ju Dong Yang, Lewis R. Roberts, Ashraf O. Abdelaziz
Publikováno v:
JCO Global Oncology, Vol , Iss 9 (2023)
PURPOSEHepatocellular carcinoma (HCC), the fourth most common cancer in Africa, has a dismal overall survival of only 3 months like in sub-Saharan Africa. This is affected by the low gross domestic product and human development index, absence of cohe
Externí odkaz:
https://doaj.org/article/bb11425805f648a1a198b8b80e8b96bf
Autor:
Walid Faraj, Mark Robson, Ayman Tawil, Victor Reuter, Rami Mahfouz, Roy Cambria, Nour Saheb, Christine S. Ferrer, Shreya Vemuri, Marita Yaghi, Mariam Kanso, Abdul Abdullah, Ghina El Nounou, Mark Jabbour, Kerri Muenkel, Kristopher Kaufman, Joe-Max Wakim, Sandy Badson, Roger Wilson, Collette Houston, Marija Drobnjak, Jamal Hoballah, Fuad N. Ziyadeh, Ghazi Zaatari, Murray Brennan, Eileen M. O'Reilly, Ali K. Abu-Alfa, Ghassan K. Abou-Alfa
Publikováno v:
JCO Global Oncology, Vol , Iss 9 (2023)
PURPOSEBiobanking helps source tissue and blood for studying cancer genomics. Access to biorepository resources in low- and middle-income countries is lacking. Memorial Sloan Kettering Cancer Center (MSK) and the American University of Beirut (AUB) e
Externí odkaz:
https://doaj.org/article/ba15bd7bb976447c8ae7bb37e2d578be
Autor:
James J. Harding, Sarina A. Piha-Paul, Ronak H. Shah, Jessica J. Murphy, James M. Cleary, Geoffrey I. Shapiro, David I. Quinn, Irene Braña, Victor Moreno, Mitesh Borad, Sherene Loi, Iben Spanggaard, Haeseong Park, James M. Ford, Mónica Arnedos, Salomon M. Stemmer, Christelle de la Fouchardiere, Christos Fountzilas, Jie Zhang, Daniel DiPrimeo, Casey Savin, S. Duygu Selcuklu, Michael F. Berger, Lisa D. Eli, Funda Meric-Bernstam, Komal Jhaveri, David B. Solit, Ghassan K. Abou-Alfa
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
In biliary tract cancer HER2 alterations correlate with poor prognosis. Here, the authors present the results of a phase II clinical trial reporting the efficacy and safety of the tyrosine kinase inhibitor neratinib in patients with HER2-mutation pos
Externí odkaz:
https://doaj.org/article/6b0c6dc798b14d37bd9664bd41aec7e1
Autor:
Nan Lin, Yongping Lin, Jianfeng Xu, Dan Liu, Diange Li, Hongyu Meng, Maxime A. Gallant, Naoto Kubota, Dhruvajyoti Roy, Jason S. Li, Emmanuel C. Gorospe, Morris Sherman, Robert G. Gish, Ghassan K. Abou‐Alfa, Mindie H. Nguyen, David J. Taggart, Richard A. Van Etten, Yujin Hoshida, Wei Li
Publikováno v:
Hepatology Communications, Vol 6, Iss 7, Pp 1753-1763 (2022)
Abstract The limited performance of guideline‐recommended abdominal ultrasound and serum alpha‐fetoprotein (AFP) highlights the urgent, unmet need for new biomarkers for more accurate detection of early hepatocellular carcinoma (HCC). To this end
Externí odkaz:
https://doaj.org/article/28c10d8ae2014899a358709c88f612fb
Autor:
Anthony B. El-Khoueiry, Tim Meyer, Ann-Lii Cheng, Lorenza Rimassa, Suvajit Sen, Steven Milwee, Robin Kate Kelley, Ghassan K. Abou-Alfa
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Patients with hepatocellular carcinoma (HCC) and Child–Pugh B liver cirrhosis have poor prognosis and are underrepresented in clinical trials. The CELESTIAL trial, in which cabozantinib improved overall survival (OS) and progres
Externí odkaz:
https://doaj.org/article/a2e4b8e7964e4b0caa19222250819492