Ixovex-1, a novel oncolytic E1B-mutated adenovirus

Autor: Mohiemen Anwar, Maja-Louise Arendt, Mohanraj Ramachandran, Anette Carlsson, Magnus Essand, Göran Akusjärvi, Ghasan Alusi, Daniel Öberg

Publikováno v: Anwar, M, Arendt, M L, Ramachandran, M, Carlsson, A, Essand, M, Akusjärvi, G, Alusi, G & Öberg, D 2022, ' Ixovex-1, a novel oncolytic E1B-mutated adenovirus ', Cancer Gene Therapy, vol. 29, pp. 1628–1635 . https://doi.org/10.1038/s41417-022-00480-3

There is a great demand for improved oncolytic viruses that selectively replicate within cancer cells while sparing normal cells. Here, we describe a novel oncolytic adenovirus, Ixovex-1, that obtains a cancer-selective replication phenotype by modul

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https://curis.ku.dk/ws/files/334014511/s41417_022_00480_3.pdf