Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Ghanem Atassi"'
Autor:
Ghanem Atassi
Publikováno v:
Advances in Oncology ISBN: 9781315076409
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27b12ad6d22684db79578aa518db2332
https://doi.org/10.4324/9781315076409-7
https://doi.org/10.4324/9781315076409-7
Autor:
Ghanem Atassi
Publikováno v:
The Nude Mouse in Oncology Research ISBN: 9781351077217
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f6f6bc7bda7d08ae316e81adaf229a0
https://doi.org/10.1201/9781351077217-15
https://doi.org/10.1201/9781351077217-15
Publikováno v:
Bulletin des Sociétés Chimiques Belges. 93:1089-1097
The synthesis and characterisation of fifteen new organotin compounds containing at least two CF3(CF2)5CH2‐CH2 groups bound to tin are described. The activity of six of these compounds towards the murine P388 lymphocytic leukaemia tumour is given.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a5a9c3efdfa328b8ed459d627a56298
https://doi.org/10.1002/bscb.19840931209
https://doi.org/10.1002/bscb.19840931209
Autor:
Michel H. J. Koch, Sylvie Michel, François Tillequin, Stéphanie Lambel, Alain Pierré, John A. Hickman, Bruno Pfeiffer, Ghanem Atassi, Valérie Pérez, Delphine Peyroulan, Stéphane Léonce
Publikováno v:
Molecular Pharmacology. 60:1383-1391
S23906-1 is a diester derivative of 1,2-dihydrobenzo[b]acronycine with an unknown mechanism of action. This cytotoxic compound was 20-fold more potent than acronycine in inhibiting the proliferation of six tumor cell lines. Using a clonogenic assay o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8bd8462327dcac3881ed333277869ee
https://doi.org/10.1124/mol.60.6.1383
https://doi.org/10.1124/mol.60.6.1383
Autor:
Dong Xiao, Wu Guangshao, Jin Ming Wu, Jian Ding, Daniel-Henri Caignard, Pierre Renard, Stéphane Léonce, Ghanem Atassi, Ying Li, Feng Shan, Jia-Xian Han
Publikováno v:
European Journal of Medicinal Chemistry. 36:469-479
A series of 12alpha-deoxoartemisinyl cyanoarylmethyl dicarboxylates (4a-4o), dicarboxylic acids 12alpha-deoxoartemisinyl ester cyanoarylmethyl amide (5a-5k), and dicarboxylic acids 12alpha-deoxoartemisinyl ester N-methylcyanoarylmethyl amide (6a-6l),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0be3316700efff1bc74f18920eec834
https://doi.org/10.1016/s0223-5234(01)01240-5
https://doi.org/10.1016/s0223-5234(01)01240-5
Autor:
Alexios-Leandros Skaltsounis, Sofia Mitaku, Pierre Renard, Prokopios Magiatis, Eleni Melliou, Ghanem Atassi, Alain Pierré
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:607-612
The synthesis and cytotoxic activity of some new 2,2-dimethyl-2H-anthra[2,3-b]pyran-6,11-diones is described. Certain compounds possess interesting activity against murine leukemia L-1210 cells. Relationships between the biological activity and the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd81894ed9cc89d075206702baa460f
https://doi.org/10.1016/s0968-0896(00)00278-9
https://doi.org/10.1016/s0968-0896(00)00278-9
Autor:
Gordon C. Tucker, Marc Bertrand, Armelle Loynel, Jean-Luc Fauchère, Jean-Michel Henlin, Annie Genton, C. Desmet-Beaufort, Jean A. Boutin, Ghanem Atassi, Nathalie Kucharczyk
Publikováno v:
The Journal of Peptide Research. 57:85-96
A complete 331 776-member library of tetrapeptides made of 24 amino acid building blocks was synthesized robotically on solid phase and subjected to a deconvolution based on the inhibitory potency of the sublibraries in a HPLC assay of the S-farnesyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec2395da9f5193c226f2fa46503384a7
https://doi.org/10.1034/j.1399-3011.2001.00787.x
https://doi.org/10.1034/j.1399-3011.2001.00787.x
Autor:
Stéphane Léonce, Konstantinos Ghirtis, Nicole Pouli, Ghanem Atassi, Daniel Henri Caignard, Panagiotis Marakos, Alexios-Leandros Skaltsounis
Publikováno v:
Journal of Heterocyclic Chemistry. 38:147-152
As part of a research program directed towards the design and synthesis of pyranoxanthones structurally related to acronycine, we present here the synthesis and cytotoxic activity of the pyranoxanthones 3 and 4 (X= H, Br; R= H, OMe; R'= H, Ac). Some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d80d1e9812675e6e61f322e8f63a6585
https://doi.org/10.1002/jhet.5570380121
https://doi.org/10.1002/jhet.5570380121
Autor:
Nadine Costes, Pierre Renard, Ghanem Atassi, Alain Pierre, Chavalit Sittisombut, Sylvie Michel, Bruno Pfeiffer, Francois Tillequin, Michel H. J. Koch
Publikováno v:
Chemical and Pharmaceutical Bulletin. 49:675-679
Condensation of 3-hydroxy-2-naphthalenecarboxylic acid with phloroglucinol afforded 1,3-dihydroxy-12H-benzo[b]xanthen-12-one. Construction of an additional dimethylpyran ring onto this skeleton, by alkylation with 3-chloro-3-methyl-1-butyne followed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa1e02d3281fd3480791b3b4c3735570
https://doi.org/10.1248/cpb.49.675
https://doi.org/10.1248/cpb.49.675
Autor:
Bruno Pfeiffer, Pierre Renard, Jean-Bernard Bongui, Francois Tillequin, Ghanem Atassi, Abdelhakim Elomri, Elisabeth Seguin, Alain Pierre
Publikováno v:
Chemical and Pharmaceutical Bulletin. 49:1077-1080
Condensation of either 2-bromobenzoic acid (4) or 2-chloro-3-nitrobenzoic acid (5) with suitable aminoquinolines 6-8 afforded phenylquinolylamines 9-13. Acid mediated cyclization gave the corresponding 12H-benzo[b][1,7]phenanthrolin-7-ones 14 and 15,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c664f55c6bed124b213a6e00e63c5786
https://doi.org/10.1248/cpb.49.1077
https://doi.org/10.1248/cpb.49.1077