Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ghaith Wedeh"'
Autor:
Michel Arock, Ghaith Wedeh, Gregor Hoermann, Siham Bibi, Cem Akin, Barbara Peter, Karoline V. Gleixner, Karin Hartmann, Joseph H. Butterfield, Dean D. Metcalfe, Peter Valent
Publikováno v:
Haematologica, Vol 103, Iss 11 (2018)
Mastocytosis is a term used to denote a group of rare diseases characterized by an abnormal accumulation of neoplastic mast cells in various tissues and organs. In most patients with systemic mastocytosis, the neoplastic cells carry activating mutati
Externí odkaz:
https://doaj.org/article/dc75137b7b6942c2804e59269d3c8d19
Autor:
Fawzia Louache, Ghaith Wedeh, Yanyan Zhang, Hosein Kouros-Mehr, Florian Beghi, Michel Arock, Viviane Baral, Liang He, Fernando Doñate, Siham Bibi, Jean-Marie Launay, Monika Wittner
Publikováno v:
Blood Advances
Blood Advances, The American Society of Hematology, 2019, 3 (4), pp.633-643. ⟨10.1182/bloodadvances.2018026179⟩
Blood Advances, 2019, 3 (4), pp.633-643. ⟨10.1182/bloodadvances.2018026179⟩
Blood Advances, The American Society of Hematology, 2019, 3 (4), pp.633-643. ⟨10.1182/bloodadvances.2018026179⟩
Blood Advances, 2019, 3 (4), pp.633-643. ⟨10.1182/bloodadvances.2018026179⟩
Antibody-drug conjugates (ADCs) are a new class of therapeutics that use antibodies to deliver potent cytotoxic drugs selectively to cancer cells. CD203c, an ecto-nucleotide pyrophosphatase-phosphodiesterase 3, is overexpressed on neoplastic mast cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d5100a397e4ff7e82ad5d03dcadbbb
https://europepmc.org/articles/PMC6391676/
https://europepmc.org/articles/PMC6391676/
Autor:
Gregor Hoermann, Cem Akin, Peter Valent, Karoline V. Gleixner, Ghaith Wedeh, Siham Bibi, Barbara Peter, Dean D. Metcalfe, Michel Arock, Joseph H. Butterfield, Karin Hartmann
Publikováno v:
Haematologica
Mastocytosis is a term used to denote a group of rare diseases characterized by an abnormal accumulation of neoplastic mast cells in various tissues and organs. In most patients with systemic mastocytosis, the neoplastic cells carry activating mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d1d4d6f814bd545290d0fdcaa4d5f9
https://pubmed.ncbi.nlm.nih.gov/29976735
https://pubmed.ncbi.nlm.nih.gov/29976735
Autor:
Andreas Reiter, Juliana Schwaab, Emir Hadzijusufovic, Sabine Cerny-Reiterer, Harald Herrmann, Gregor Hoermann, Deepti Radia, Katharina Blatt, Hans-Peter Horny, Gregor Eisenwort, Irina Sadovnik, James E. Bradner, Leonhard Müllauer, Johannes Zuber, Michel Arock, Peter Valent, Ghaith Wedeh, Wolfgang R. Sperr, Thomas Hoffmann
Publikováno v:
Leukemia. 29:2230-2237
Advanced systemic mastocytosis (SM) is a life-threatening neoplasm characterized by uncontrolled growth and accumulation of neoplastic mast cells (MCs) in various organs and a poor survival. So far, no curative treatment concept has been developed fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f06a5f96e995ed2e9028403928c717c
https://doi.org/10.1038/leu.2015.138
https://doi.org/10.1038/leu.2015.138
Autor:
Ghaith Wedeh, Jean-Marie Launay, Siham Bibi, Yanyan Zhang, Caroline Hugonin, Thomas Wurdinger, Mallorie Depond Mangean, Sjoerd van Rijn, Michel Arock, Liang He, Fawzia Louache
Publikováno v:
Oncotarget, 7(50), 82985-83000. Impact Journals
Bibi, S, Zhang, Y, Hugonin, C, Mangean, M D, He, L, Wedeh, G, Launay, J-M, Van Rijn, S, Würdinger, T, Louache, F & Arock, M 2016, ' A new humanized in vivo model of KIT D816V+ advanced systemic mastocytosis monitored using a secreted luciferase ', Oncotarget, vol. 7, no. 50, pp. 82985-83000 . https://doi.org/10.18632/oncotarget.12824
Oncotarget
Bibi, S, Zhang, Y, Hugonin, C, Mangean, M D, He, L, Wedeh, G, Launay, J-M, Van Rijn, S, Würdinger, T, Louache, F & Arock, M 2016, ' A new humanized in vivo model of KIT D816V+ advanced systemic mastocytosis monitored using a secreted luciferase ', Oncotarget, vol. 7, no. 50, pp. 82985-83000 . https://doi.org/10.18632/oncotarget.12824
Oncotarget
Systemic mastocytosis are rare neoplasms characterized by accumulation of mast cells in at least one internal organ. The majority of systemic mastocytosis patients carry KIT D816V mutation, which activates constitutively the KIT receptor. Patient wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4dfc5ca7e12f4ee2ae1bf5552dd8771
https://research.vumc.nl/en/publications/9cdee694-0660-4144-935a-71c66994bbaf
https://research.vumc.nl/en/publications/9cdee694-0660-4144-935a-71c66994bbaf
Publikováno v:
Archives of virology. 161(1)
Infection by hepatitis C virus (HCV) is a major public-health problem. Chronic infection often leads to cirrhosis, steatosis, and hepatocellular carcinoma. The life cycle of HCV depends on the host cell machinery and involves intimate interaction bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465829c7f7c954c9fc5a5342b6cea577
https://pubmed.ncbi.nlm.nih.gov/26449956
https://pubmed.ncbi.nlm.nih.gov/26449956
Autor:
Harald Herrmann, Rosine Saleh, Emir Hadzijusufovic, Hélène Merle-Béral, Magali Legarff-Tavernier, Peter Valent, Frédéric Subra, Michel Arock, Florence Nguyen-Khac, Patrice Dubreuil, Katharina Blatt, Catherine Blanc, Sabine Cerny-Reiterer, Michael Willmann, Elise Chapiro, Vanessa Desplat, Siham Bibi, Thomas Rülicke, Ghaith Wedeh, Patrick Bonnemye, Sylvie Jeanningros, Irina Sadovnik
Publikováno v:
Blood
Blood, American Society of Hematology, 2014, 124 (1), pp.111-120. ⟨10.1182/blood-2013-10-534685⟩
Blood, 2014, 124 (1), pp.111-120. ⟨10.1182/blood-2013-10-534685⟩
Blood, American Society of Hematology, 2014, 124 (1), pp.111-120. 〈10.1182/blood-2013-10-534685〉
Blood, American Society of Hematology, 2014, 124 (1), pp.111-120. ⟨10.1182/blood-2013-10-534685⟩
Blood, 2014, 124 (1), pp.111-120. ⟨10.1182/blood-2013-10-534685⟩
Blood, American Society of Hematology, 2014, 124 (1), pp.111-120. 〈10.1182/blood-2013-10-534685〉
International audience; In systemic mastocytosis (SM), clinical problems arise from factor-independent proliferation of mast cells (MCs) and the increased release of mediators by MCs, but no human cell line model for studying MC activation in the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deea2cdbac6242536566e735e4494f8c
https://pubmed.ncbi.nlm.nih.gov/24677542
https://pubmed.ncbi.nlm.nih.gov/24677542