Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ghadi Antoun"'
Autor:
Ghadi Antoun, Ujval Anilkumar, Mohamed Ariff Iqbal, Shawn McGuirk, Jacob Wong, Karan Gandhi, Richard B. Richardson, Julie St-Pierre, David A. Patten, Ruth S. Slack, Gaganvir Parmar, Mary-Ellen Harper
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1868:118854
Mitochondria are highly dynamic organelles. Alterations in mitochondrial dynamics are causal or are linked to numerous neurodegenerative, neuromuscular, and metabolic diseases. It is generally thought that cells with altered mitochondrial structure a
Autor:
Ruth S. Slack, Thrush Ab, Paulina Lau, David A. Patten, Majid Nikpay, Jörg Hager, Mary-Ellen Harper, DeVlugt C, Robert Dent, Gibbings D, Brittany Beauchamp, Pascal Imbeault, Ghadi Antoun, Mauger Jf, Reshke R, Ruth McPherson, Armand Valsesia, Éric Doucet, Robert Boushel, Osama Y. Al-Dirbashi
Publikováno v:
International Journal of Obesity (2005)
Background/Objectives: Inter-individual variability in weight loss during obesity treatment is complex and poorly understood. Here we use whole body and tissue approaches to investigate fuel oxidation characteristics in skeletal muscle fibers, cells
Autor:
Michael A. Rudnicki, C. Florian Bentzinger, Frank Grosveld, Ghadi Antoun, Hang Yin, Alessandra Pasut, Mary-Ellen Harper, Patrick Seale, Wilfred F. J. van IJcken, Vahab D. Soleimani, Stephanie Thorn, Pasan Fernando, Robert A. deKemp, Robert Boushel
Publikováno v:
Cell Metabolism, 17(2), 210-224. Cell Press
SummaryBrown adipose tissue (BAT) is an energy-dispensing thermogenic tissue that plays an important role in balancing energy metabolism. Lineage-tracing experiments indicate that brown adipocytes are derived from myogenic progenitors during embryoni
Publikováno v:
The Journal of Neuroscience. 32:4867-4877
Activation of the MAPK/ERK signaling cascade in the suprachiasmatic nucleus (SCN) is a key event that couples light to circadian clock entrainment. However, we do not fully understand the mechanisms that shape the properties of MAPK/ERK signaling in
Publikováno v:
Canadian Journal of Diabetes. 42:313-316.e1
Autor:
Ruth McPherson, Alyssa C. Peixoto, Ruth S. Slack, Fiona McMurray, David A. Patten, Ghadi Antoun, Mary-Ellen Harper, Robert Dent, A. Brianne Thrush
Publikováno v:
Diabetologia. 58(12)
Skeletal muscle mitochondrial dysfunction has been documented in patients with type 2 diabetes mellitus; however, specific respiratory defects and their mechanisms are poorly understood. The aim of the current study was to examine oxidative phosphory
Autor:
Nathan McIntosh, A. Brianne Thrush, Mary-Elizabeth Patti, Mary-Ellen Harper, Ghadi Antoun, Brittany Beauchamp, Jessica K. Quizi, Osama Y. Al-Dirbashi
Publikováno v:
Bioscience Reports
We show that in utero undernutrition is associated with impaired cardiac muscle energetics and increased plasma short-chain acylcarnitines in adult mice. Findings suggest that in utero undernutrition is associated with maladaptive programming process
Autor:
Martin Holcik, Mary-Ellen Harper, Jason R. Vanstone, Pranesh Chakraborty, Hugh J. McMillan, Stephanie Redpath, Jason Brophy, Matthew A. Lines, Turaya Naas, Hussein Daoud, Skye McBride, Ghadi Antoun, David A. Dyment, Jean Michaud
Publikováno v:
JIMD Reports ISBN: 9783662504086
Mutations of FBXL4, which encodes an orphan mitochondrial F-box protein, are a recently identified cause of encephalomyopathic mtDNA depletion. Here, we describe the detailed clinical and biochemical phenotype of a neonate presenting with hyperlactat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79165c88429d79814131c06f67e2214b
https://doi.org/10.1007/8904_2015_491
https://doi.org/10.1007/8904_2015_491
Autor:
Ghadi Antoun, Fiona McMurray, A. Brianne Thrush, David A. Patten, Alyssa C. Peixoto, Ruth S. Slack, Ruth McPherson, Robert Dent, Mary-Ellen Harper
Publikováno v:
Diabetologia. 59:396-397
Publikováno v:
Clinical and investigative medicine. Medecine clinique et experimentale. 37(4)
The 2013 joint Canadian Society of Clinician Investigators (CSCI)–Clinical Investigator Trainee Association of Canada/Association des cliniciens-chercheurs en formation du Canada (CITAC/ACCFC) annual general meeting(AGM) was held in Ottawa, Septemb