Výsledky vyhledávání - "Ghada Abou Lteif"

Inhibition of mammalian target of rapamycin signaling by everolimus induces senescence in adult T-cell leukemia/lymphoma and apoptosis in peripheral T-cell lymphomas

Autor: Ali Bazarbachi, Ghada Abou-Lteif, Ghassan Dbaibo, Nadine Darwiche, Ansam Sinjab, Mirella Bou Chedid, Olivier Hermine

Publikováno v: International Journal of Cancer. 129:1006-1017

HTLV-I-associated adult T-cell leukemia/lymphoma (ATL) and human T-cell lymphotropic virus type I (HTLV-I)-negative peripheral T-cell lymphomas carry poor prognosis mainly because of acquired resistance to chemotherapy. We have shown that this diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22133d6dae0525efc6b1492819bcc417
https://doi.org/10.1002/ijc.25742

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Reactive oxygen species mediate N-(4-hydroxyphenyl)retinamide-induced cell death in malignant T cells and are inhibited by the HTLV-I oncoprotein Tax

Autor: Ghada Abou-Lteif, Ali Bazarbachi, Nadine Darwiche

Publikováno v: Leukemia. 21:261-269

N-(4-hydroxyphenyl)retinamide (HPR) is a synthetic retinoid that inhibits growth of many human tumor cells, including those resistant to natural retinoids. HPR is an effective chemopreventive agent for prostate, cervix, breast, bladder, skin and lung

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390200ffeef3bfe96da0d1bc03af8a7e
https://doi.org/10.1038/sj.leu.2404472

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Stage-specific effect of N-(4-hydroxyphenyl)retinamide on cell growth in squamous cell carcinogenesis

Autor: Imane Chakroun, Ghada Abou-Lteif, Asma Hatoum, Fadia R. Homaidan, Nadine Darwiche, Mohamed Kabbout

Publikováno v: Molecular Carcinogenesis. 40:12-23

ASUMENDI A, 2002, BRIT J CANCER, V12, P1951; BOISE LH, 1993, CELL, V74, P597, DOI 10.1016-0092-8674(93)90508-N; Bruno S, 2002, CARCINOGENESIS, V23, P447, DOI 10.1093-carcin-23.3.447; Chambon P, 1996, FASEB J, V10, P940; Chan LNL, 1997, LEUKEMIA LYMPH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::052fcaf64942aaa8bb2628dc1305723e
https://doi.org/10.1002/mc.20016

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Purified salograviolide a isolated from centaurea ainetensis causes growth inhibition and apoptosis in neoplastic epidermal cells

Autor: Akram Ghantous, Ahmad Abou Tayyoun, Najat A. Saliba, Ghada Abou Lteif, Nadine Darwiche, Marwan El-Sabban, Hala Gali-Muhtasib

Publikováno v: International Journal of Oncology.

Many of the best-selling anticancer drugs are plant-derived. We tested for the anticancer properties of extracts isolated from Centaurea ainetensis, a plant species endemic to Lebanon and which is often used in folk medicine. We performed bioassay-gu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b471badcaa7705feba6829689c3a288
https://doi.org/10.3892/ijo.32.4.841

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Regulation of ultraviolet B radiation-mediated activation of AP1 signaling by retinoids in primary keratinocytes

Autor: Rami Doueiri, Ghada Abou-Lteif, Hisham Bazzi, Hala Gali-Muhtasib, Samar W. Maalouf, Nadine Darwiche, Asma Hatoum, Lara El-Touni

Publikováno v: Radiation research. 163(3)

The main cause of skin cancer and photo-aging is chronic exposure to ultraviolet B (UVB) radiation. Such damage can be ameliorated by retinoid treatment. UVB-radiation-induced skin carcinogenesis is associated with the induction of activator protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a03bf06622553f2e491026efec7317
https://pubmed.ncbi.nlm.nih.gov/15733037

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Stage-specific effect of N-(4-hydroxyphenyl)retinamide on cell growth in squamous cell carcinogenesis

Autor: Mohamed, Kabbout, Asma, Hatoum, Ghada, Abou-Lteif, Imane, Chakroun, Fadia R, Homaidan, Nadine, Darwiche

Publikováno v: Molecular carcinogenesis. 40(1)

Squamous cell carcinoma (SCC) is the most prevalent form of epithelial cancer. SCC results when normal epithelial cells undergo multiple neoplastic changes that culminate in the evolution of an invasive cancer. Retinoids are commonly used as chemopre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e66b22dd26b12f191f3eff1879365de0
https://pubmed.ncbi.nlm.nih.gov/15108326

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Human T-cell lymphotropic virus type I-transformed T-cells have a partial defect in ceramide synthesis in response to N-(4-hydroxyphenyl)retinamide

Autor: Ghada Abou-Lteif, Ali Bazarbachi, Ghassan Dbaibo, Nadine Darwiche, Lina Kozhaya, Ahmad Abou Tayyoun, Tarek Najdi

Publikováno v: Biochemical Journal. 444:619-619

Treatment with the synthetic retinoid HPR [N-(4-hydroxyphenyl)-retinamide] causes growth arrest and apoptosis in HTLV-I (human T-cell lymphotropic virus type-I)-positive and HTLV-I-negative malignant T-cells [8]. It was observed that HPR-mediated gro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1092f330cf06671544b7075baf896c75
https://doi.org/10.1042/bj4440619u

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